scholarly journals Nucleus incertus corticotrophin-releasing factor 1 receptor signalling regulates alcohol seeking in rats

2016 ◽  
Vol 22 (6) ◽  
pp. 1641-1654 ◽  
Author(s):  
Leigh C. Walker ◽  
Hanna E. Kastman ◽  
Jan A. Koeleman ◽  
Craig M. Smith ◽  
Christina J. Perry ◽  
...  
Keyword(s):  
Receptor Signalling ◽  
Corticotrophin Releasing Factor ◽  
Nucleus Incertus ◽  
Alcohol Seeking

The role of corticotrophin-releasing factor in stress-induced relapse to alcohol-seeking behavior in rats

2000 ◽  
Vol 150 (3) ◽  
pp. 317-324 ◽  
Author(s):  
A. D. Lê ◽  
S. Harding ◽  
W. Juzytsch ◽  
J. Watchus ◽  
U. Shalev ◽  
...  
Keyword(s):  
Corticotrophin Releasing Factor ◽  
Seeking Behavior ◽  
Alcohol Seeking

Nucleus incertus Orexin2 receptors mediate alcohol seeking in rats

2016 ◽  
Vol 110 ◽  
pp. 82-91 ◽  
Author(s):  
Hanna E. Kastman ◽  
Anna Blasiak ◽  
Leigh Walker ◽  
Marcin Siwiec ◽  
Elena V. Krstew ◽  
...  
Keyword(s):  
Nucleus Incertus ◽  
Alcohol Seeking

scholarly journals Involvement of the Nucleus Incertus and Relaxin-3/RXFP3 Signaling System in Explicit and Implicit Memory

2021 ◽  
Vol 15 ◽  
Author(s):  
Isis Gil-Miravet ◽  
Aroa Mañas-Ojeda ◽  
Francisco Ros-Bernal ◽  
Esther Castillo-Gómez ◽  
Hector Albert-Gascó ◽  
...  
Keyword(s):  
Theta Rhythm ◽  
Past Research ◽  
Memory Formation ◽  
Corticotrophin Releasing Factor ◽  
Peptidergic Innervation ◽  
Neuromedin B ◽  
Nucleus Incertus ◽  
Hippocampal Theta ◽  
With Memory

Telencephalic cognitive and emotional circuits/functions are strongly modulated by subcortical inputs. The main focus of past research on the nature of this modulation has been on the widespread monoamine projections to the telencephalon. However, the nucleus incertus (NI) of the pontine tegmentum provides a strong GABAergic and peptidergic innervation of the hippocampus, basal forebrain, amygdala, prefrontal cortex, and related regions; and represents a parallel source of ascending modulation of cognitive and emotional domains. NI GABAergic neurons express multiple peptides, including neuromedin-B, cholecystokinin, and relaxin-3, and receptors for stress and arousal transmitters, including corticotrophin-releasing factor and orexins/hypocretins. A functional relationship exists between NI neurons and their associated peptides, relaxin-3 and neuromedin-B, and hippocampal theta rhythm, which in turn, has a key role in the acquisition and extinction of declarative and emotional memories. Furthermore, RXFP3, the cognate receptor for relaxin-3, is a Gi/o protein-coupled receptor, and its activation inhibits the cellular accumulation of cAMP and induces phosphorylation of ERK, processes associated with memory formation in the hippocampus and amygdala. Therefore, this review summarizes the role of NI transmitter systems in relaying stress- and arousal-related signals to the higher neural circuits and processes associated with memory formation and retrieval.

The role of central corticotrophin‐releasing factor receptor signalling in plasma glucose maintenance through ghrelin secretion in calorie‐restricted mice

2021 ◽  
Vol 33 (3) ◽  
Author(s):  
Risa Kimura ◽  
Daisuke Kondo ◽  
Shota Takemi ◽  
Miyuki Fujishiro ◽  
Shinji Tsukahara ◽  
...  
Keyword(s):  
Plasma Glucose ◽  
Receptor Signalling ◽  
Corticotrophin Releasing Factor ◽  
Ghrelin Secretion

scholarly journals Heterogeneous responses of nucleus incertus neurons to corticotrophin-releasing factor and coherent activity with hippocampal theta rhythm in the rat

2013 ◽  
Vol 591 (16) ◽  
pp. 3981-4001 ◽  
Author(s):  
Sherie Ma ◽  
Anna Blasiak ◽  
Francisco E. Olucha-Bordonau ◽  
Anthony J. M. Verberne ◽  
Andrew L. Gundlach
Keyword(s):  
Theta Rhythm ◽  
Hippocampal Theta Rhythm ◽  
Corticotrophin Releasing Factor ◽  
Nucleus Incertus ◽  
Hippocampal Theta

1714: Corticotrophin Releasing Factor Reduces the Micturition Threshold when Administered at Central, Spinal, and Peripheral Levels

2004 ◽  
Vol 171 (4S) ◽  
pp. 453-454 ◽  
Author(s):  
Adam P. Klausner ◽  
Tomi Streng ◽  
Jerry Raju ◽  
Jeremy B. Tuttle ◽  
Karl-Erik Andersson ◽  
...  
Keyword(s):  
Corticotrophin Releasing Factor

Role of the proto-oncogene product Cbl in B cell receptor signalling

1997 ◽  
Vol 56 (1-3) ◽  
pp. 4
Author(s):  
L Smit
Keyword(s):  
B Cell ◽  
Cell Receptor ◽  
B Cell Receptor ◽  
Receptor Signalling

Genetic variants at the Wnt/[beta]-catenin and oestrogen receptor signalling pathways are associated with low bone mineral density in dancers

2016 ◽  
Author(s):  
Tania Amorim ◽  
Cecilia Duraes ◽  
Jose Maia ◽  
Machado Jose Carlos ◽  
Luisa Nogueira ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Genetic Variants ◽  
Oestrogen Receptor ◽  
Signalling Pathways ◽  
Beta Catenin ◽  
Mineral Density ◽  
Receptor Signalling ◽  
Low Bone Mineral Density

Activators of AMP-activated protein kinase regulate adipocyte aldosterone secretion and mineralocorticoid receptor signalling

2015 ◽  
Author(s):  
Anna White ◽  
Aurelie Nguyen Dinh Cat ◽  
Augusto Montezano ◽  
Ian Salt ◽  
Rhian Touyz
Keyword(s):  
Protein Kinase ◽  
Mineralocorticoid Receptor ◽  
Aldosterone Secretion ◽  
Receptor Signalling ◽  
Amp Activated Protein Kinase
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