scholarly journals Comparison of saliva cotinine and exhaled carbon monoxide concentrations when smoking and after being offered dual nicotine replacement therapy in pregnancy

Addiction ◽  
2021 ◽  
Author(s):  
Bhavandeep Slaich ◽  
Ravinder Claire ◽  
Joanne Emery ◽  
Sarah Lewis ◽  
Sue Cooper ◽  
...  
Keyword(s):  
Carbon Monoxide ◽  
Replacement Therapy ◽  
Nicotine Replacement Therapy ◽  
Nicotine Replacement ◽  
Saliva Cotinine ◽  
Exhaled Carbon Monoxide ◽  
In Pregnancy

Comparison of a Daily Smartphone App and Retrospective Questionnaire Measures of Adherence to Nicotine Replacement Therapy within Pregnant Women (Preprint)

2021 ◽  
Author(s):  
Joanne Emery ◽  
Yue Huang ◽  
Felix Naughton ◽  
Sue Cooper ◽  
Lisa McDaid ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Replacement Therapy ◽  
Nicotine Replacement Therapy ◽  
Face Validity ◽  
Smartphone App ◽  
Nicotine Replacement ◽  
Saliva Cotinine ◽  
Reporting Rates ◽  
Retrospective Questionnaire ◽  
Collection Methods

BACKGROUND Few studies have investigated how to best measure adherence to smoking cessation medications, but continuous usage measures are recommended. OBJECTIVE In this first study of its kind, we compared methods for measuring adherence to nicotine replacement therapy (NRT), investigating the completeness and validity of data collected from daily assessments using a smartphone app versus data collected from retrospective questionnaires. METHODS Women aged ≥16, who were daily smokers <25 weeks pregnant, were offered cessation counselling and encouraged to use NRT. Women set quit dates (QD) and, for 28 days afterwards, were asked to report NRT use daily to a smartphone app and to questionnaires administered in-person or remotely at 7 and 28 days. For both data collection methods, we provided up to £25 in compensation for time taken providing research data. Data completeness and NRT use reported to app and questionnaires were compared. For each method, we also correlated mean daily nicotine doses reported within 7 days of QD with Day 7 saliva cotinine concentrations. RESULTS Of 438 women assessed for eligibility, 40 participated and 35 accepted NRT. More participants (31/35) submitted NRT usage data to the app by Day 28 (median days submitted=25 [IQR 11]) than completed the Day 28 questionnaire (24/35). Data submitted to the app showed a lower reported duration of NRT use compared to the questionnaire (median days NRT for app=24 [IQR 10.25]; questionnaire=28 [4.75], P=.007), and there appeared to be specific cases of overreporting to the questionnaire. Mean daily nicotine doses (mg) between QD and Day 7 were lower when calculated using app data (median mg for app=40 [52.1]; questionnaire=40 [63.1], P=.001), and some large outliers were evident for the questionnaire. Mean daily nicotine doses, adjusted for cigarettes smoked, were not associated with cotinine concentrations for either method (app r=0.184, P=.55; questionnaire r=0.031, P=.92). CONCLUSIONS Daily assessment of NRT use via a smartphone app facilitated more complete data (a higher response rate) than questionnaires, and reporting rates over 28 days were encouraging among pregnant women. Although data from neither method was significantly associated with cotinine concentrations, app data had better face validity; retrospective questionnaires appeared to overestimate NRT use for some.

Association between nicotine replacement therapy use in pregnancy and smoking cessation

2013 ◽  
Vol 132 (3) ◽  
pp. 660-664 ◽  
Author(s):  
Leonie S. Brose ◽  
Andy McEwen ◽  
Robert West
Keyword(s):  
Smoking Cessation ◽  
Replacement Therapy ◽  
Nicotine Replacement Therapy ◽  
Nicotine Replacement ◽  
In Pregnancy

scholarly journals Exposure to Tobacco, Environmental Tobacco Smoke and Nicotine in Pregnancy: A Pragmatic Overview of Reviews of Maternal and Child Outcomes, Effectiveness of Interventions and Barriers and Facilitators to Quitting

2020 ◽  
Vol 17 (6) ◽  
pp. 2034 ◽  
Author(s):  
Gillian S. Gould ◽  
Alys Havard ◽  
Ling Li Lim ◽  
Ratika Kumar ◽  
Keyword(s):  
Smoking Cessation ◽  
Health Outcomes ◽  
Pregnant Women ◽  
Replacement Therapy ◽  
Nicotine Replacement Therapy ◽  
Systematic Reviews ◽  
Nicotine Replacement ◽  
Increased Risk ◽  
Pertinent Data ◽  
In Pregnancy

The aim of this review of reviews was to collate the latest evidence from systematic reviews about the maternal and child health outcomes of being exposed to tobacco and nicotine during pregnancy; the effectiveness of interventions designed to reduce these exposures, and barriers to and facilitators of smoking cessation during pregnancy. Two databases were searched to obtain systematic reviews published from 2010 to 2019. Pertinent data from 76 articles were summarized using a narrative synthesis (PROSPERO reference: CRD42018085896). Exposure to smoke or tobacco in other forms during pregnancy is associated with an increased risk of obstetric complications and adverse health outcomes for children exposed in-utero. Counselling interventions are modestly effective, while incentive-based interventions appear to substantially increase smoking cessation. Nicotine replacement therapy is effective during pregnancy but the evidence is not conclusive. Predictors and barriers to smoking cessation in pregnancy are also discussed. Smoking during pregnancy poses substantial risk to mother’s and child’s health. Psychosocial interventions and nicotine replacement therapy (NRT) appear to be effective in helping pregnant women quit smoking. Barriers to smoking cessation must be identified and steps taken to eradicate them in order to reduce smoking among pregnant women. More research is needed on smoking cessation medications and e-cigarettes.

Randomized, double-blind, placebo-controlled trial of nicotine replacement therapy in pregnancy

2001 ◽  
Vol 62 (4) ◽  
pp. 274-278 ◽  
Author(s):  
Bhushan Kapur ◽  
Richard Hackman ◽  
Peter Selby ◽  
Julia Klein ◽  
Gideon Koren
Keyword(s):  
Replacement Therapy ◽  
Nicotine Replacement Therapy ◽  
Controlled Trial ◽  
Double Blind ◽  
Nicotine Replacement ◽  
Double Blind Placebo ◽  
In Pregnancy

scholarly journals Knowledge and Education as Barriers and Facilitators to Nicotine Replacement Therapy Use for Smoking Cessation in Pregnancy: A Qualitative Study with Health Care Professionals

2019 ◽  
Vol 16 (10) ◽  
pp. 1814 ◽  
Author(s):  
Ross Thomson ◽  
Lisa McDaid ◽  
Joanne Emery ◽  
Felix Naughton ◽  
Sue Cooper ◽  
...  
Keyword(s):  
Smoking Cessation ◽  
Replacement Therapy ◽  
Nicotine Replacement Therapy ◽  
Health Care Professionals ◽  
Educational Interventions ◽  
Barriers And Facilitators ◽  
Nicotine Replacement ◽  
Smoking During Pregnancy ◽  
Stop Smoking ◽  
In Pregnancy

Smoking during pregnancy is a leading cause of negative pregnancy and perinatal outcomes. While UK guidelines recommend nicotine replacement therapy (NRT) for smoking cessation during pregnancy, adherence to NRT is generally low and may partially explain why NRT appears less effective in pregnancy compared to non-pregnant smokers. This study aimed to identify and describe factors associated with NRT adherence from a health professional’s perspective. Two focus groups and one expert group were conducted with 26 professionals involved in antenatal stop smoking services and the data were analysed thematically using a template methodology. From our analyses, we extracted two main themes: (i) ‘Barriers to NRT use in pregnancy’ explores the issues of how misinformation and unrealistic expectations could discourage NRT use, while (ii) ‘Facilitators to NRT use in pregnancy’ describes the different information, and modes of delivery, that stop smoking professionals believe will encourage correct and sustained NRT use. Understanding the barriers and facilitators to improve NRT adherence may aid the development of educational interventions to encourage NRT use and improve outcomes for pregnant women wanting to stop smoking.

Nicotine Replacement Therapy in Pregnancy and Major Congenital Anomalies in Offspring

PEDIATRICS ◽  
2015 ◽  
Vol 135 (5) ◽  
pp. 859-867 ◽  
Author(s):  
N. N. Dhalwani ◽  
L. Szatkowski ◽  
T. Coleman ◽  
L. Fiaschi ◽  
L. J. Tata
Keyword(s):  
Replacement Therapy ◽  
Nicotine Replacement Therapy ◽  
Congenital Anomalies ◽  
Nicotine Replacement ◽  
In Pregnancy

Efficacy and safety of nicotine replacement therapy for smoking cessation in pregnancy: systematic review and meta-analysis

Addiction ◽  
2010 ◽  
Vol 106 (1) ◽  
pp. 52-61 ◽  
Author(s):  
Tim Coleman ◽  
Catherine Chamberlain ◽  
Sue Cooper ◽  
Jo Leonardi-Bee
Keyword(s):  
Systematic Review ◽  
Smoking Cessation ◽  
Replacement Therapy ◽  
Nicotine Replacement Therapy ◽  
Meta Analysis ◽  
Efficacy And Safety ◽  
Nicotine Replacement ◽  
In Pregnancy
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