Influence of anti‐inflammatory irrigant on substance P expression for single‐visit root canal treatment of teeth with irreversible pulpitis

2019 ◽  
Vol 46 (1) ◽  
pp. 73-81
Author(s):  
Lavanya Bamini ◽  
I Anand Sherwood ◽  
Paul V. Abbott ◽  
Ramesh Uthandakalaipandian ◽  
Vijay Velu
2019 ◽  
Vol 46 (1) ◽  
pp. 17-25 ◽  
Author(s):  
J. Evangelin ◽  
I. Anand Sherwood ◽  
Paul V. Abbott ◽  
Ramesh Uthandakalaipandian ◽  
Vijay Velu

2017 ◽  
Vol 5 (1-2) ◽  
pp. 45-48
Author(s):  
Md Abdur Rahim ◽  
Md Nurul Amin ◽  
Khurshid Mahmood ◽  
Sibbir Ahmed Osmani ◽  
Abul Kalam Md Faruq

Objective: The present prospective comparative clinical trial was undertaken to compare the outcomes of single and two-visit root canal treatment of irreversible pulpitis. Methodology: This prospective study was conducted in the Department of Conservative Dentistry and Endodontics of Dhaka Dental College on patients who presented with pain due to irreversible pulpitis. Patients with single-rooted teeth with uncomplicated canal and full-formed apex having irreversible pulpitis were included. However, pregnant women or patients under treatment of antibiotics, cortiosteiods or suffering from any systemic diseases or immuno-compromised patients or patients having teeth with calcified canal or periodontal disease were excluded. A total of 80 patients who met the eligibility criteria were consecutively included and were randomly assigned to either one-visit (n = 40) or two-visit (n = 40) treatment groups. Data were kept on pulp vitality status, the presence or absence of pre-operative pain and degree of post obturation pain at 6, 12, 24, 48 hours and 1 week postoperatively. The outcome variable was intensity of pain which was measured using a visual analogue scale (VAS) as 0 = no pain, 1 = slight pain or discomfort, 2 = moderate pain relieved by analgesic, 3 = moderate to severe pain not completely relieved by analgesics and 4 = severe pain or swelling not relieved by analgesics and required unscheduled visit. Result: Forty percent of the patients in the two-visit group did not have any pain (measured in terms of visual analogue scale) at 12 hours compared to 25% in the single visit group, although the difference did not turn significant (p = 0.580). Likewise the proportion of patients without pain in the two-visit group was considerably higher (52.5%) at 24 hours than that in the single-visit group (45%) (p = 0.852). Improvement in pain sensation was reported to be significantly higher in the two-visit group (as 95% of the patients did not complain any pain) at 48 hours than that in the single-visit group (80% of the patients did not complain any pain) (p = 0.015). None of the patients of either group complained of pain one week postoperatively. Conclusion: Compared to single-visit, two-visit root canal treatment showed better results in terms of intensity of post-obturation pain at 12, 24 and 48 hours after root canal treatment for irreversible pulpitis. Ibrahim Card Med J 2015; 5 (1&2): 45-48


2016 ◽  
Vol 04 (01) ◽  
pp. 044-048
Author(s):  
Kamal Nabhi ◽  
Ajay Chhabra ◽  
Varun Jindal ◽  
Simran Singh ◽  

Abstract Purpose: Prevention and management of postendodontic pain (PEP) is an integral part of endodontic treatment. NSAIDs such as Ibuprofen, Ketorolac are the most common medications used for managing pain after root canal treatment. So the purpose of this study was to compare the effect of pain relief on regular versus on demand prescription of ibuprofen after single-visit root canal treatment in teeth with irreversible pulpitis. Materials & Methodology: The study was performed on twenty patients. Root canal treatment was performed and all the patients were given a ‘‘rescue bag’’ that contained 8 tablets of 400 mg ibuprofen and then divided into two groups. In the group 1- patients were instructed to use ibuprofen tablets if they felt pain and in the group 2- patients were instructed to take ibuprofen regularly after every 6 hours for at least three days. Patients were instructed to complete a form to rate their pain at 24 and 48 hours after the root canal treatment and were also asked to record the number of analgesic tablets they had taken. Records were collected and statistically analysed. Results: The patients’ pain levels in groups 1 and 2 were not significantly different at 24 and 48 hours after root canal treatment. The number of analgesic medications used by the patients in group 2 was significantly higher than the other group. Conclusion: Regular prescription of ibuprofen had no significant effect on postoperative pain compared with on-demand use of ibuprofen in teeth with irreversible pulpitis


Medicina ◽  
2021 ◽  
Vol 57 (6) ◽  
pp. 573
Author(s):  
João Miguel Santos ◽  
Joana F. Pereira ◽  
Andréa Marques ◽  
Diana B. Sequeira ◽  
Shimon Friedman

Background and Objectives: Symptomatic irreversible pulpitis in permanent mature teeth is a common indication for nonsurgical root canal treatment (NSRCT), but contemporary studies have reported on vital pulp therapy (VPT) applied in such teeth as a less invasive treatment. This systematic review assessed the outcomes of VPT, including partial and full pulpotomy performed with hydraulic calcium silicate cements (HCSCs) in permanent mature posterior teeth diagnosed with symptomatic irreversible pulpitis. Materials and Methods: The PRISMA guidelines were followed. The search strategy included PubMed®, EMBASE, Cochrane library and grey literature electronic databases. The quality assessment of the identified studies followed the Cochrane Collaboration Risk of Bias, ROBINS-I and Newcastle–Ottawa Scale tools. Results: The search of primary databases identified 142 articles, of which 9 randomized controlled trials and 3 prospective cohort studies were selected for review. The risk-of-bias was assessed as ‘high’ or ‘serious’, ‘fair’, and ‘low’ for three, seven and two articles, respectively. One to five years after VPT using HCSCs, the success rates mostly ranged from 78 to 90%. Based on two articles, the outcomes of the VPT and NSRCT were comparable at one and five years. Despite the necessity for the intra-operative pulp assessment in VPT procedures, the majority of the studies did not fully report on this step or on the time needed to achieve hemostasis. Small sample sizes, of under 23 teeth, were reported in three studies. Conclusions: The reviewed 12 articles reported favorable outcomes of the VPT performed with HCSCs in permanent mature posterior teeth with symptomatic irreversible pulpitis, with radiographic success in the range of 81 to 90%. Two articles suggested comparable outcomes of the VPT and root canal treatment. Universal case selection and outcome criteria needs to be established for VPT when considered as an alternative to NSRCT. This evidence supports the need for further research comparing longer-term outcomes of both of the treatment modalities.


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