Noninvasive prenatal testing (NIPT) in Western Australia; Considerations in clinical practice

2014 ◽  
Vol 54 (5) ◽  
pp. 487-489 ◽  
Author(s):  
Sarah Long ◽  
Jack Goldblatt
Medicine ◽  
2016 ◽  
Vol 95 (41) ◽  
pp. e5126 ◽  
Author(s):  
Guijie Qi ◽  
Jianping Yi ◽  
Baosheng Han ◽  
Heng Liu ◽  
Wanru Guo ◽  
...  

2017 ◽  
Vol 66 (2) ◽  
pp. 33-39 ◽  
Author(s):  
Tatyana K Kascheeva ◽  
Tatyana V Kuznetzova ◽  
Vladislav S Baranov

Advantages and drawbacks of noninvasive prenatal testing (NIPT) of chromosomal anomalies are briefly reviewed. Material supply, employment issues, financial and management problems in European countries and in Russia are discussed. Many problems are rising under implementation of this new method into the clinical practice.


Author(s):  
D. O. Korostin ◽  
D. A. Plakhina ◽  
V. A. Belova

The last couple of years have witnessed the rapid development of prenatal molecular-based screening for fetal aneuploidies that utilizes the analysis of cell-free DNA circulating in the bloodstream of a pregnant woman. The present review looks at the potential and limitations of such testing and the possible causes of false-positive and false-negative results. The review also describes the underlying principles of data acquisition and analysis the testing involves. In addition, we talk about the opinions held by the expert community and some aspects of legislation on the use of noninvasive prenatal testing (NIPT) in clinical practice in the countries where NIPT is much more widespread than in Russia.


Author(s):  
Robert M. Hodapp ◽  
Ellen G. Casale

Compared to parents of children with other types of intellectual disabilities, parents of children with Down syndrome experience less stress and more rewards, although this “Down syndrome advantage” mostly occurs compared to parents of children with autism and before groups are equated. Behaviorally, children with Down syndrome display more sociable interactional styles and baby-faced facial features, along with fewer instances of severe behavior problems. Demographically, parents of children with (versus without) Down syndrome average 5 years older when giving birth; parents are more often well educated, married, of higher socioeconomic status, and they likely provide these children greater financial and cultural resources. In most industrialized societies, rates of Down syndrome seem steady, with easily available, noninvasive prenatal testing counteracted by increasing numbers of women giving birth at older ages. Parenting children with Down syndrome relates to characteristics of children, their parents, and society, all of which intersect in important, underexplored ways.


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