Melatonin prevents dexamethasone-induced testicular oxidative stress and germ cell apoptosis in golden hamster,Mesocricetus auratus

Andrologia ◽  
2014 ◽  
pp. n/a-n/a ◽  
Author(s):  
Arun Mukherjee ◽  
Chandana Haldar ◽  
Dipanshu Kumar Vishwas
Keyword(s):  
Oxidative Stress ◽  
Germ Cell ◽  
Golden Hamster ◽  
Cell Apoptosis ◽  
Mesocricetus Auratus ◽  
Germ Cell Apoptosis

scholarly journals Isoflurane impairs oogenesis through germ cell apoptosis in C. elegans

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Tao Zhang ◽  
Cheng Ni ◽  
Cheng Li ◽  
Pan Lu ◽  
Dan Chen ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Germ Cell ◽  
Fluorescence Imaging ◽  
Cell Apoptosis ◽  
Germ Cell Apoptosis ◽  
C Elegans ◽  
Interaction Studies ◽  
Acetyl Cysteine ◽  
Induced Changes ◽  
And Oxidative Stress

AbstractAnesthetic isoflurane has been reported to induce toxicity. However, the effects of isoflurane on fecundity remain largely unknown. We established a system in C. elegans to investigate the effects of isoflurane on oogenesis. Synchronized L4 stage C. elegans were treated with 7% isoflurane for 4 h. Dead cells, ROS, embryos, and unfertilized eggs laid by hermaphrodites were measured by fluorescence imaging and counting. The C. elegans with losses of ced-3, cep-1, abl-1, male C. elegans, and oxidative stress inhibitor N-acetyl-cysteine were used in the interaction studies. We found that isoflurane decreased the numbers of embryos and unfertilized eggs and increased the levels of dead cells and ROS in C. elegans. The isoflurane-induced impairment of oogenesis was associated with abl-1, ced-3, but not cep-1. N-acetyl-cysteine attenuated the isoflurane-induced impairment of oogenesis in C. elegans. Mating with male C. elegans did not attenuate the isoflurane-induced changes in oogenesis. These findings suggest that isoflurane may impair oogenesis through abl-1- and ced-3-associated, but not cep-1-associated, germ cell apoptosis and oxidative stress, pending further investigation. These studies will promote more research to determine the potential effects of anesthesia on fecundity.

Spermatogenesis disorder caused by T-2 toxin is associated with germ cell apoptosis mediated by oxidative stress

2019 ◽  
Vol 251 ◽  
pp. 372-379 ◽  
Author(s):  
Xu Yang ◽  
Xuliang Zhang ◽  
Jian Zhang ◽  
Qiang Ji ◽  
Wanyue Huang ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Germ Cell ◽  
Cell Apoptosis ◽  
Germ Cell Apoptosis

Caspase-9-dependent pathway to murine germ cell apoptosis: mediation by oxidative stress, BAX, and caspase 2

2007 ◽  
Vol 328 (2) ◽  
pp. 411-419 ◽  
Author(s):  
Jeffrey J. Lysiak ◽  
Shuqiu Zheng ◽  
Robin Woodson ◽  
Terry T. Turner
Keyword(s):  
Oxidative Stress ◽  
Germ Cell ◽  
Cell Apoptosis ◽  
Caspase 9 ◽  
Germ Cell Apoptosis ◽  
Caspase 2 ◽  
Dependent Pathway

scholarly journals The ameliorative effect of carvacrol on oxidative stress and germ cell apoptosis in testicular tissue of adult diabetic rats

2019 ◽  
Vol 111 ◽  
pp. 568-578 ◽  
Author(s):  
Hamed Shoorei ◽  
Arash Khaki ◽  
Amir Afshin Khaki ◽  
Alireza Ali Hemmati ◽  
Maryam Moghimian ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Germ Cell ◽  
Cell Apoptosis ◽  
Testicular Tissue ◽  
Diabetic Rats ◽  
Germ Cell Apoptosis ◽  
Ameliorative Effect

Panax ginseng ameliorate toxic effects of cadmium on germ cell apoptosis, sperm quality, and oxidative stress in male Wistar rats

Toxin Reviews ◽  
2021 ◽  
pp. 1-13
Author(s):  
Saeedeh Shojaeepour ◽  
Fariba Sharififar ◽  
Tahereh Haghpanah ◽  
Maryam Iranpour ◽  
Masoud Imani ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Germ Cell ◽  
Panax Ginseng ◽  
Cell Apoptosis ◽  
Wistar Rats ◽  
Sperm Quality ◽  
Toxic Effects ◽  
Germ Cell Apoptosis ◽  
Male Wistar Rats ◽  
And Oxidative Stress
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