Avoidance of primary site adjuvant radiotherapy following transoral robotic surgery: a cohort study

2022 ◽  
Author(s):  
Laurent Fradet ◽  
Emma Charters ◽  
Kan Gao ◽  
Catriona Froggatt ◽  
Carsten Palme ◽  
...  
Head & Neck ◽  
2021 ◽  
Author(s):  
Mikkel H. H. Larsen ◽  
Susanne I. Scott ◽  
Hani I. Channir ◽  
Anne K. Ø. Madsen ◽  
Birgitte W. Charabi ◽  
...  

2017 ◽  
Vol 7 (3) ◽  
pp. e157-e158 ◽  
Author(s):  
Eric Ojerholm ◽  
J. Nicholas Lukens ◽  
Peter H. Ahn ◽  
Geoffrey Geiger ◽  
Samuel Swisher-McClure ◽  
...  

2017 ◽  
Vol 143 (3) ◽  
pp. 267 ◽  
Author(s):  
Kyle M. Hatten ◽  
Bert W. O’Malley ◽  
Andres M. Bur ◽  
Mihir R. Patel ◽  
Christopher H. Rassekh ◽  
...  

BMJ Open ◽  
2019 ◽  
Vol 9 (12) ◽  
pp. e035431 ◽  
Author(s):  
John R de Almeida ◽  
Christopher W Noel ◽  
Maria Veigas ◽  
Rosemary Martino ◽  
Douglas B Chepeha ◽  
...  

IntroductionCarcinomas of unknown primary site (CUP) of the head and neck have historically been worked up and managed heterogeneously. Failure to identify a primary site may result in large radiotherapy mucosal volumes. Transoral approaches such as Transoral Robotic Surgery (TORS) may improve the yield of identifying hidden primaries. We aim to assess the oncological and functional outcomes of a combined treatment approach with TORS and tailored radiotherapy.Methods and analysisTwenty-five patients with metastatic squamous cell carcinoma to the neck without clinical or radiographic evidence of a primary site will be enrolled in a phase II trial. Patients will undergo a diagnostic or therapeutic approach with TORS based on specific algorithms incorporating tailored radiotherapy according to the location and laterality of the primary tumour. The primary outcome is to evaluate the out-of-field failure rate over a 2-year period. Secondary outcomes include identification rates, survival outcomes, patient reported outcomes and functional swallowing outcomes.Ethics and disseminationThe University Health Network Research Ethics Board approved this study (ID 15–9767). The results will be published in an open access journal.Trial registration numberNCT03281499.


Head & Neck ◽  
2021 ◽  
Author(s):  
Vishal R. Dhere ◽  
Chase E. Escott ◽  
Sibo Tian ◽  
Jeffrey M. Switchenko ◽  
James P. Bell ◽  
...  

2013 ◽  
Vol 2013 ◽  
pp. 1-4 ◽  
Author(s):  
Waleed F. Mourad ◽  
Dukagjin M. Blakaj ◽  
Rafi Kabarriti ◽  
Rebekah Young ◽  
Rania A. Shourbaji ◽  
...  

Purpose. Transoral robotic surgery (TORS) has increased in popularity in the management of squamous cell carcinoma of the head and neck. However, TORS does not address the neck or retropharyngeal nodes (RPN). In the current report, we highlight the impact of the lack of adjuvant radiotherapy on RPN recurrence after TORS.Materials and Methods. A 58-year-old Caucasian male presented with squamous cell carcinoma of the head and neck of unknown primary. He was offered radiotherapy as a definitive management for clinical stage T0N2aM0, stage IVA, but he opted to left neck dissection. Follow-up PET-CT scan revealed recurrence in the left base of tongue and right level II lymph node. He was offered radiotherapy which he declined and opted to TORS and right neck dissection. Follow-up PET-CT scan showed recurrence in left RPN for which he underwent salvage concurrent chemoradiotherapy to 70 Gy.Results. After a followup of 9 months from the date of salvage chemoradiotherapy completion, the patient is with no evidence of disease.Conclusions. TORS followed by adjuvant radiotherapy seems reasonable in the context of squamous cell carcinoma of the head and neck due to the odds of RPN involvement. Further reports are warranted to optimize post-TORS adjuvant treatment.


2013 ◽  
Vol 74 (S 01) ◽  
Author(s):  
Christopher Rassekh ◽  
Shayanne Lajud ◽  
Courtney Shires ◽  
Laurie Loevner ◽  
Ara Chalian ◽  
...  

2015 ◽  
Vol 76 (S 01) ◽  
Author(s):  
Christopher Rassekh ◽  
Gregory Weinstein ◽  
Laurie Loevner ◽  
Ara Chalian ◽  
Bert O'Malley

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