scholarly journals Pain during medical abortion in early pregnancy in teenage and adult women

2020 ◽  
Vol 99 (12) ◽  
pp. 1603-1610 ◽  
Author(s):  
Venla Kemppainen ◽  
Maarit Mentula ◽  
Vilja Palkama ◽  
Oskari Heikinheimo
Keyword(s):  
Early Pregnancy ◽  
Medical Abortion ◽  
Adult Women

Efficacy of Sublingual Administration Misoprostol 600 mcg Versus 800 mcg for Induced Abortion in Women with Early Pregnancy Loss: A Randomized Controlled Trial

2021 ◽  
Vol 104 (10) ◽  
pp. 1626-1631
Keyword(s):  
Side Effects ◽  
Early Pregnancy ◽  
Pregnancy Loss ◽  
Controlled Trial ◽  
Medical Abortion ◽  
Abortion Rate ◽  
Sublingual Administration ◽  
Early Pregnancy Loss ◽  
Significant Difference ◽  
Misoprostol Group

Objective: To compare the complete abortion rate, the induction-to-abortion time, and side effects between 600 mcg and 800 mcg misoprostol sublingually. Materials and Methods: Total, of 108 pregnant women with gestational age less than 12 weeks with early pregnancy loss from March 2020 to February 2021 at the Department of Obstetrics and Gynecology, Queen Savang Vadhana Memorial Hospital, were included. For group 1 (n=54), 600 mcg misoprostol was administrated sublingually. For group 2 (n=54), 800 mcg misoprostol was administrated sublingually. If the abortion did not occur, the repeated misoprostol in the same dose would be administrated sublingually every 6 hours for a maximum of three doses. Results: There was no significant difference in the complete abortion rate between the two groups (55.6% in the 600 mcg misoprostol group, 64.7% in the 800 mcg misoprostol group, p=0.339, and 95% CI 0.082 to 1.862). The induction-to-abortion time was 9.5 hours (IQR 6.75 to 48.00) in the 600 mcg misoprostol group and 10 hours (IQR 6.00 to 60.00) in the 800 mcg misoprostol group. The side effects of both groups were similar, included abdominal pain, diarrhea, nausea and vomiting, fever, heavy bleeding, and headache. Conclusion: The efficacy of the 600 mcg misoprostol was noninferior to 800 mcg misoprostol. The adverse effects were similar in both groups. Mean induction-to-abortion time was also similar in both groups. Keywords: Early pregnancy loss; Misoprostol; Medical abortion

Medical Abortion in Early Pregnancy

2009 ◽  
pp. 111-134 ◽  
Author(s):  
Mitchell D. Creinin ◽  
Kristina Gemzell Danielsson
Keyword(s):  
Early Pregnancy ◽  
Medical Abortion

High prevalence of suboptimal vitamin B12 status in young adult women of South Asian and European ethnicity

2015 ◽  
Vol 40 (12) ◽  
pp. 1279-1286 ◽  
Author(s):  
Teo A.W. Quay ◽  
Theresa H. Schroder ◽  
Marta Jeruszka-Bielak ◽  
Wangyang Li ◽  
Angela M. Devlin ◽  
...  
Keyword(s):  
Young Adult ◽  
Vitamin B12 ◽  
South Asian ◽  
Early Pregnancy ◽  
Adult Women ◽  
Young Adult Women ◽  
Convenience Sample ◽  
Supplement Use ◽  
Common Genetic Variants ◽  
B12 Deficiency

Suboptimal vitamin B12 (B12) status has been associated with an increased risk of congenital anomalies, preterm birth, and childhood insulin resistance. South Asians – Canada’s largest minority group – and women of reproductive age are vulnerable to B12 deficiency. This study aimed to assess the prevalence of and factors associated with B12 deficiency and suboptimal B12 status in a convenience sample of young adult women of South Asian and European descent in Metro Vancouver. We measured serum B12, holotranscobalamin, plasma methylmalonic acid, red blood cell and plasma folate, and hematologic parameters in 206 nonpregnant, healthy women aged 19–35 years. Categorization for B12 status adhered to serum B12 cutoffs for deficiency (<148 pmol/L) and suboptimal B12 status (148–220 pmol/L). We collected demographic, lifestyle, and dietary intake data and conducted genotyping for common genetic variants linked to B-vitamin metabolism. The prevalence of deficiency and suboptimal B12 status were 14% and 20%, respectively. Serum vitamin B12 concentrations were negatively associated with oral contraceptive use and first-generation immigrant status, and positively with dietary B12 intake and B12 supplement use. The prevalence of B12 inadequacy in this sample of highly educated women is higher than in the general Canadian population. In light of maternal and fetal health risks associated with B12 inadequacy in early-pregnancy, practitioners should consider monitoring B12 status before and during early pregnancy, especially in immigrants and women with low dietary B12 intakes including non-users of vitamin supplements.

scholarly journals Safety, efficacy and acceptability of medical abortion with mifepristone and misoprostol in Nepalese women

1970 ◽  
Vol 2 (2) ◽  
pp. 54-58 ◽  
Author(s):  
Veena Shrivastava
Keyword(s):  
Side Effects ◽  
Early Pregnancy ◽  
Medical Abortion ◽  
Safe Abortion ◽  
Major Health ◽  
Medical Termination Of Pregnancy ◽  
Medical Termination ◽  
Normal Period ◽  
A Prospective Study ◽  
Major Health Issue

Unsafe abortion is a major health issue. Therefore safe abortion services which is effective. acceptable and techniquely easy to perform should be available. Aim- To confirm effectiveness, side effects, safety and patient satisfaction with medical termination of early pregnancy. Methods- It was a prospective study 150 women who were less than 63 days pregnant and consented for medical termination of pregnancy were given! 200mg 0 Mefepristone orally and 48 hrs later 800 micro gram Misoprostol was inserted vaginally. They were followed up in 14 days. Bleeding, pain G.I symptoms any other side effects were recorded. Abortion was complete or not was confirmed clinically and by USG. Failure and success was documented depending upon need for surgical evacuation. Results- The success rate with this regime was 92.6% and failure rate was 7.3%. There were no major side effects with Mifepristone. The average bleeding after misoprostol insertion was 10 days and 80% women had more bleeding than normal period. All of them had pain. Only 13.3% needed analgesic. women (96%) were satisfied with the method. Conclusion- combination of mifepristone and misoprostol is a safe and effective of early pregnancy Keywords- medical termination, pregnancy, mifepristone, misoprostol.   doi:10.3126/njog.v2i2.1456 N. J. Obstet. Gynaecol 2007 Nov-Dec; 2 (2): 54 - 58

scholarly journals Comparison of rates of adverse events in adolescent and adult women undergoing medical abortion: population register based study

BMJ ◽  
2011 ◽  
Vol 342 (apr19 2) ◽  
pp. d2111-d2111 ◽  
Author(s):  
M. Niinimaki ◽  
S. Suhonen ◽  
M. Mentula ◽  
E. Hemminki ◽  
O. Heikinheimo ◽  
...  
Keyword(s):  
Adverse Events ◽  
Medical Abortion ◽  
Adult Women ◽  
Population Register
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