scholarly journals Letter: nonselective beta-blockers, endoscopic therapy and portal vein thrombosis in cirrhosis. Authors' reply

2019 ◽  
Vol 49 (10) ◽  
pp. 1371-1372
Author(s):  
Filipe Nery ◽  
Dominique Valla
Keyword(s):  
Portal Vein ◽  
Portal Vein Thrombosis ◽  
Endoscopic Therapy ◽  
Beta Blockers ◽  
Vein Thrombosis

Tu1565 - Nonselective Beta-Blockers are Associated with an Increased Risk of Portal Vein Thrombosis in Adults with Cirrhosis: A Case Control Study

2018 ◽  
Vol 154 (6) ◽  
pp. S-1253 ◽  
Author(s):  
Teresa Menadier ◽  
Sa Ra Park ◽  
Javelle A. Wynter ◽  
Jonathan G. Stine ◽  
Patrick G. Northup
Keyword(s):  
Portal Vein ◽  
Portal Vein Thrombosis ◽  
Case Control Study ◽  
Beta Blockers ◽  
Case Control ◽  
Vein Thrombosis ◽  
Increased Risk ◽  
Control Study

scholarly journals The use of nonselective beta blockers is a risk factor for portal vein thrombosis in cirrhotic patients

2018 ◽  
Vol 24 (1) ◽  
pp. 25 ◽  
Author(s):  
Rosa Zampino ◽  
Rita Lebano ◽  
Nicola Coppola ◽  
Margherita Macera ◽  
Anna Grandone ◽  
...  
Keyword(s):  
Risk Factor ◽  
Portal Vein ◽  
Portal Vein Thrombosis ◽  
Beta Blockers ◽  
Vein Thrombosis ◽  
Cirrhotic Patients

scholarly journals Recurrent esophagogastric variceal bleeding due to portal vein thrombosis caused by protein S deficiency

2018 ◽  
Vol 06 (11) ◽  
pp. E1283-E1288 ◽  
Author(s):  
Haoxiong Zhou ◽  
Jieying Xuan ◽  
Xianyi Lin ◽  
Yunwei Guo
Keyword(s):  
Portal Vein ◽  
Portal Vein Thrombosis ◽  
Variceal Bleeding ◽  
Endoscopic Therapy ◽  
Protein S ◽  
Protein S Deficiency ◽  
Esophageal Variceal ◽  
Vein Thrombosis ◽  
S Deficiency

Abstract Background and study aims Esophagogastric variceal bleeding (EGVB) is common in patients with portal vein thrombosis (PVT). Hereditary deficiencies in natural anticoagulant proteins, such as protein S, might contribute to PVT. However, recurrent EGVB caused by PVT in patients with protein S deficiency is seldom reported. Herein, we present the case of a 38-year-old man with protein S deficiency complicated with PVT. The patient suffered recurrent EGVB for 7 years. He underwent splenectomy plus pericardial revascularization and sequential endoscopic therapy, including one gastric variceal obturation (GVO) procedure and two esophageal variceal ligations (EVL) to eradicate the varices. Rivaroxaban was administrated to reduce risk of thrombotic events. The patient is currently well without rebleeding after 1 year of follow-up. To our knowledge there is no consensus on management of recurrent EGVB on the basis of thrombophilia complicated with PVT. According to our practice, sequential endoscopic therapy combined with anticoagulant appears to be effective and safe.

Nonselective beta-blockers and development of portal vein thrombosis in liver cirrhosis: a systematic review and meta-analysis

2019 ◽  
Vol 13 (4) ◽  
pp. 468-481 ◽  
Author(s):  
Xiangbo Xu ◽  
Xiaozhong Guo ◽  
Valerio De Stefano ◽  
Gilberto Silva-Junior ◽  
Hemant Goyal ◽  
...  
Keyword(s):  
Systematic Review ◽  
Liver Cirrhosis ◽  
Portal Vein ◽  
Portal Vein Thrombosis ◽  
Beta Blockers ◽  
Meta Analysis ◽  
Vein Thrombosis
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