scholarly journals BI21: Targeted chemotherapy‐induced psoriasis successfully treated with acitretin

2021 ◽  
Vol 185 (S1) ◽  
pp. 151-152
Keyword(s):  
Targeted Chemotherapy

Treatment of a BRAF V600E Positive Ameloblastoma in a Pediatric Patient with MEK Inhibitor Monotherapy

FACE ◽  
2021 ◽  
pp. 273250162110051
Author(s):  
Steven Daws ◽  
Kongkrit Chaiyasate ◽  
Arshi Lehal
Keyword(s):  
Mapk Pathway ◽  
Case Reports ◽  
Radical Resection ◽  
Mek Inhibitor ◽  
Braf V600e Mutation ◽  
Braf V600e ◽  
Targeted Chemotherapy ◽  
Odontogenic Epithelium ◽  
Genetic Landscape ◽  
Frequent Presence

Ameloblastomas are uncommon tumors of the odontogenic epithelium standardly treated with radical resection. Recent studies of the genetic landscape of ameloblastoma have revealed the frequent presence of the BRAF V600E mutation, suggesting a possible role for targeted chemotherapy. We present the case of a primary mandibular ameloblastoma found in a 13-year-old female with confirmed BRAF V600E mutation. Prior to invasive surgical intervention she was treated for 8 weeks with the MEK inhibitor trametinib, but her tumor demonstrated little radiographic, clinical, or histologic response. Previous case reports have shown ameloblastoma in adult patients to be responsive to other agents targeting the MAPK pathway. Our observations in the presented case demonstrate the need for further research into the utility of targeted chemotherapy in ameloblastoma treatment.

Monoclonal Antibody-conjugated Polyphosphoester-hyd-DOX Prodrug Nanoparticles for Targeted Chemotherapy of Liver Cancer Cells

2021 ◽  
Author(s):  
Ya-Kui Huang ◽  
Hong-Rui Tian ◽  
Ming-Zu Zhang ◽  
Jin-Lin He ◽  
Jian Liu ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Liver Cancer ◽  
Cancer Cells ◽  
Targeted Chemotherapy ◽  
Liver Cancer Cells

Construction and evaluation of hyaluronic acid-based copolymers as a targeted chemotherapy drug carrier for cancer therapy

2020 ◽  
Vol 31 (30) ◽  
pp. 305702
Author(s):  
Yuting Tang ◽  
Minglong Chen ◽  
Qian Xie ◽  
Lu Li ◽  
Lei Zhu ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Cancer Therapy ◽  
Drug Carrier ◽  
Targeted Chemotherapy ◽  
Chemotherapy Drug

scholarly journals Homotypic Cell Membrane-Cloaked Biomimetic Nanocarrier for the Targeted Chemotherapy of Hepatocellular Carcinoma

Theranostics ◽  
2019 ◽  
Vol 9 (20) ◽  
pp. 5828-5838 ◽  
Author(s):  
Xiaojun Liu ◽  
Yingxue Sun ◽  
Shushen Xu ◽  
Xiaonan Gao ◽  
Fanpeng Kong ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Cell Membrane ◽  
Targeted Chemotherapy

Targeted chemotherapy with encapsulated, genetically modified cells engineered to produce CYP2B1, an ifosfamide converting enzyme

1998 ◽  
Vol 114 ◽  
pp. A648
Author(s):  
P. Müller ◽  
P. Karle ◽  
R. Jesnowski ◽  
Robert Saller ◽  
S. Mitzner ◽  
...  
Keyword(s):  
Genetically Modified ◽  
Targeted Chemotherapy ◽  
Converting Enzyme

Application of bacterial directed enzyme prodrug therapy as a targeted chemotherapy approach in a mouse model of breast cancer

2021 ◽  
pp. 120931
Author(s):  
Niloufar Hosseini Giv ◽  
Ahmad Reza Bahrami ◽  
Maryam M. Matin
Keyword(s):  
Breast Cancer ◽  
Mouse Model ◽  
Targeted Chemotherapy ◽  
Enzyme Prodrug Therapy

scholarly journals Targeted Chemotherapy for Unresectable Primary and Metastatic Liver Cancer

1994 ◽  
Vol 33 (2) ◽  
pp. 133-137 ◽  
Author(s):  
Toshimitsu Konno ◽  
Yousuke Kai ◽  
Ryoichi Yamashita ◽  
Akinori Nagamitsu ◽  
Masami Kimura
Keyword(s):  
Liver Cancer ◽  
Targeted Chemotherapy ◽  
Metastatic Liver Cancer ◽  
Metastatic Liver

The APEX1/miRNA-27a-5p axis plays key roles in progression, metastasis and targeted chemotherapy of gastric cancer

2021 ◽  
Vol 599 ◽  
pp. 120446
Author(s):  
Huimin He ◽  
Fengying Song ◽  
Qian Gao ◽  
Zheng Lu ◽  
Yue Yuan ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Targeted Chemotherapy
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