scholarly journals Pharmacological characterization of the first in class clinical candidate PF-05190457: a selective ghrelin receptor competitive antagonist with inverse agonism that increases vagal afferent firing and glucose-dependent insulin secretionex vivo

2016 ◽  
Vol 173 (9) ◽  
pp. 1452-1464 ◽  
Author(s):  
J Kong ◽  
J Chuddy ◽  
I A Stock ◽  
P M Loria ◽  
S V Straub ◽  
...  
Keyword(s):  
Pharmacological Characterization ◽  
Competitive Antagonist ◽  
Ghrelin Receptor ◽  
Inverse Agonism ◽  
Vagal Afferent ◽  
Clinical Candidate

Pharmacological characterization of the ghrelin receptor antagonist, GSK1614343 in rat RC-4B/C cells natively expressing GHS type 1a receptors

2011 ◽  
Vol 650 (1) ◽  
pp. 178-183 ◽  
Author(s):  
Elisabetta Perdonà ◽  
Federico Faggioni ◽  
Alberto Buson ◽  
Fabio Maria Sabbatini ◽  
Corrado Corti ◽  
...  
Keyword(s):  
Receptor Antagonist ◽  
C Cells ◽  
Pharmacological Characterization ◽  
Ghrelin Receptor ◽  
Ghrelin Receptor Antagonist

scholarly journals Pharmacological characterization of the ghrelin receptor mediating its inhibitory action on inflammatory pain in rats

Amino Acids ◽  
2012 ◽  
Vol 43 (4) ◽  
pp. 1751-1759 ◽  
Author(s):  
Valeria Sibilia ◽  
Francesca Pagani ◽  
Emanuela Mrak ◽  
Elisa Dieci ◽  
Giovanni Tulipano ◽  
...  
Keyword(s):  
Inflammatory Pain ◽  
Inhibitory Action ◽  
Pharmacological Characterization ◽  
Ghrelin Receptor

Rational Design, Synthesis, and Pharmacological Characterization of Novel Ghrelin Receptor Inverse Agonists as Potential Treatment against Obesity-Related Metabolic Diseases

2018 ◽  
Vol 61 (24) ◽  
pp. 11039-11060 ◽  
Author(s):  
Antoine Daina ◽  
Claudio Giuliano ◽  
Claudio Pietra ◽  
Junbo Wang ◽  
Yushi Chi ◽  
...  
Keyword(s):  
Rational Design ◽  
Metabolic Diseases ◽  
Potential Treatment ◽  
Pharmacological Characterization ◽  
Design Synthesis ◽  
Inverse Agonists ◽  
Ghrelin Receptor

Pharmacological characterization of the selective 11β-hydroxysteroid dehydrogenase 1 inhibitor, BI 135585, a clinical candidate for the treatment of type 2 diabetes

2015 ◽  
Vol 746 ◽  
pp. 50-55 ◽  
Author(s):  
Bradford S. Hamilton ◽  
Frank Himmelsbach ◽  
Herbert Nar ◽  
Annette Schuler-Metz ◽  
Paula Krosky ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Hydroxysteroid Dehydrogenase ◽  
Pharmacological Characterization ◽  
Clinical Candidate

P.1.c.022 Pharmacological characterization of ghrelin receptor in rat adenoma anterior pituitary cell line, RC-4B/C

2008 ◽  
Vol 18 ◽  
pp. S232-S233
Author(s):  
E. Perdona ◽  
F. Faggioni ◽  
C. Corti ◽  
C. Cavanni
Keyword(s):  
Cell Line ◽  
Anterior Pituitary ◽  
Pituitary Cell ◽  
Pharmacological Characterization ◽  
Ghrelin Receptor ◽  
Anterior Pituitary Cell

Pharmacological characterization of Tibouchina granulosa

Planta Medica ◽  
2014 ◽  
Vol 80 (16) ◽  
Author(s):  
CC Guilhon ◽  
A Minho ◽  
AS Barros ◽  
PD Fernandes
Keyword(s):  
Pharmacological Characterization
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