Determinants of platelet count in pediatric patients with congenital cyanotic heart disease: Role of immature platelet fraction

2017 ◽  
Vol 13 (1) ◽  
pp. 118-123 ◽  
Author(s):  
Randa M. Matter ◽  
Iman A. Ragab ◽  
Alaa M. Roushdy ◽  
Ahmed G. Ahmed ◽  
Hanan H. Aly ◽  
...  
Keyword(s):  
Platelet Count ◽  
Heart Disease ◽  
Pediatric Patients ◽  
Cyanotic Heart Disease ◽  
Immature Platelet Fraction ◽  
Congenital Cyanotic Heart Disease

Cyanosis and Clipping: Noninfectious Aneurysm in a Patient with 22q11.2 Deletion Syndrome

2021 ◽  
pp. 1-5
Author(s):  
Bhanu Jayanand Sudhir ◽  
Sanjay Honavalli Murali ◽  
Jaypalsinh Gohil ◽  
Rajalakshmi Poyuran ◽  
Manikantan Sethuraman ◽  
...  
Keyword(s):  
Heart Disease ◽  
Cerebral Aneurysms ◽  
Artery Aneurysm ◽  
22Q11.2 Deletion Syndrome ◽  
Neurological Deficits ◽  
Deletion Syndrome ◽  
Anterior Communicating Artery ◽  
Cyanotic Heart Disease ◽  
22Q11.2 Deletion ◽  
Congenital Cyanotic Heart Disease

Noninfectious cerebral aneurysms are rare in patients with congenital cyanotic heart disease. We present a patient with DiGeorge/velocardiofacial syndrome with a complex congenital cyanotic heart disease with a ruptured anterior communicating artery aneurysm. The 10-year-old child was managed by surgical clipping of the aneurysm. Surgical challenges included prominent veins in the Sylvian fissure, difficulty in differentiating arterial and venous bleed, and anesthetic risks. The patient recovered without any neurological deficits. This is the first report of a patient with 22q11.2 deletion syndrome, with a noninfectious cerebral aneurysm.

Selective coronary angiography via antegrade venous route in congenital cyanotic heart disease

1993 ◽  
Vol 28 (2) ◽  
pp. 179-182 ◽  
Author(s):  
Yunus S. Loya ◽  
Robin J. Pinto ◽  
Dhruman M. Desai ◽  
Usha Sundaram ◽  
Ajit R. Bhagwat ◽  
...  
Keyword(s):  
Heart Disease ◽  
Coronary Angiography ◽  
Cyanotic Heart Disease ◽  
Selective Coronary Angiography ◽  
Congenital Cyanotic Heart Disease

ONE OF THE EARLIEST CLINICAL AND POSTMORTEM DESCRIPTIONS OF CYANOTIC CONGENITAL HEART DISEASE REPORTED IN THE UNITED STATES

PEDIATRICS ◽  
1969 ◽  
Vol 43 (4) ◽  
pp. 577-577
Author(s):  
T. E. C.
Keyword(s):  
Heart Disease ◽  
New England ◽  
Maternal Care ◽  
Congenital Heart ◽  
The United States ◽  
Cyanotic Congenital Heart Disease ◽  
Cyanotic Heart Disease ◽  
Considerable Time ◽  
Congenital Cyanotic Heart Disease ◽  
Unusual Shape

The first volume of the New England Journal of Medicine and Surgery, which appeared in 1812, contained this succinct description of congenital cyanotic heart disease in a young girl: S.R. when born was for a considerable time supposed to be dead-did not cry, or evince any living actions. The lungs were artificially inflated for several minutes and life at length appeared, but very feebly.-A livid countenance, with frequent syncope took place.-With great maternal care the infant was kept alive, and as she grew became remarkably sprightly and active. When two years old (she) was unusually intelligent and fond of exercise.-As she advanced in age her fondness for violent exercise in playing often exposed her danger, as these efforts never failed to produce syncope and a kind of convulsion, laughing, crying, any emotion of mind, also brought on the syncope, from which after falling into a horizontal position, she generally soon recovered.-Her countenance, all times blueish and livid, was in these fits extremely extremely so. Her nails were always of the colour of litmus, or perhaps a little nearer to violet. After death the thorax was examined-it was of an unusual shape, being more cylindrical than common, and the lungs having less the form of a cloven hoof, when inflated, than they usually assume.-The heart was very small. In place of a right auricle was observed a small appendage like the edge of that portion of the heart, not capable of containing more than one fourth its usual contents.

Tuberculosis and congenital cyanotic heart disease

1954 ◽  
Vol 16 (4) ◽  
pp. 528-534 ◽  
Author(s):  
Robert D. Sloan ◽  
C.Rollins Hanlon ◽  
H.William Scott
Keyword(s):  
Heart Disease ◽  
Cyanotic Heart Disease ◽  
Congenital Cyanotic Heart Disease

ATYPICAL RUBEOSIS IRIDIS IN CONGENITAL CYANOTIC HEART DISEASE

2009 ◽  
Vol 55 (4) ◽  
pp. 581-585 ◽  
Author(s):  
JENS CHRISTIAN KRARUP
Keyword(s):  
Heart Disease ◽  
Cyanotic Heart Disease ◽  
Rubeosis Iridis ◽  
Congenital Cyanotic Heart Disease

scholarly journals Problems with Antiplatelet Therapy in Children with Cyanotic Heart Disease

1977 ◽  
Author(s):  
A.H. Sutor ◽  
B. Schmidt ◽  
H.P. Lorenz ◽  
J. Vogt
Keyword(s):  
Platelet Count ◽  
Heart Disease ◽  
Antiplatelet Therapy ◽  
Bleeding Time ◽  
Fibrinolytic Therapy ◽  
Antiplatelet Drugs ◽  
Cyanotic Heart Disease ◽  
Consumption Coagulopathy ◽  
Thromboembolic Complications ◽  
Cardiac Decompensation

Children with cyanotic heart disease are endangered by thromboembolic complications. However, in our 17 patients we could not find laboratory evidence for consumption coagulopathy but found evidence for isolated platelet consumption with increased platelet turnover. We therefore applied antiplatelet drugs (acetylsalicylic acid and dipyridamol) in order to prevent thromboembolic complications. With antiplatelet therapy the platelet count increased in average, however, 12 of 17 children with cyanotic heart disease did not show prolongation of the bleeding time as did controls. There is strong evidence that in these children an adequate blood-level of antiplatelet drugs was not obtained either by non-absorption (due to cardiac decompensation) or because of relative underdosage (due to increased platelet turnover) of the antiplatelet drugs. 2 of these patients who had a normal bleeding time, inspite of antiplatelet drugs, suffered from thromboembolic complications requiring fibrinolytic therapy. As a concequence we increase the dosage of antiplatelet drugs when the bleeding time does not prolong.

Accuracy of pulse oximeters at low oxygen saturations in children with congenital cyanotic heart disease: An observational study

2019 ◽  
Vol 29 (6) ◽  
pp. 597-603 ◽  
Author(s):  
Eun‐Hee Kim ◽  
Ji‐Hyun Lee ◽  
In‐Kyung Song ◽  
Hee‐Soo Kim ◽  
Young‐Eun Jang ◽  
...  
Keyword(s):  
Heart Disease ◽  
Observational Study ◽  
Cyanotic Heart Disease ◽  
Low Oxygen ◽  
Congenital Cyanotic Heart Disease ◽  
Pulse Oximeters
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