Kidney injury biomarkers after cardiac angiography in children with congenital heart disease

2019 ◽  
Vol 14 (6) ◽  
pp. 1087-1093 ◽  
Author(s):  
Masashi Nishida ◽  
Shingo Kubo ◽  
Yuma Morishita ◽  
Kosuke Nishikawa ◽  
Kazuyuki Ikeda ◽  
...  
Author(s):  
Fatma Ukil Isildak ◽  
Yasemin Yavuz ◽  
Omer Faruk Savluk ◽  
Nihat Cine ◽  
Ufuk Uslu

Objectives: This study aimed to evaluate whether the development of acute kidney injury (AKI) was associated with preoperative albumin/prealbumin levels and other clinical features in pediatric patients who underwent open-heart surgery for congenital heart disease. Patients and Methods: In this retrospective cohort, patients aged between 1 – 60 months who underwent open-heart surgery (complete correction surgery) with a diagnosis of congenital heart disease at the XXXXXX, between January 1, 2018 - December 31, 2020, were retrospectively included (n = 100). Patient demographics, diagnoses, surgical characteristics, and laboratory findings were recorded and analyzed. Results: Mean age was 13.63 ± 12.05 (range 1.5 - 60) months. eGFR was decreased by more than 50% in 13% of the cases. Compared to the preoperative period, it was found that urea (24th and 48th hour) and creatinine levels increased significantly (p< 0.001, for each), and eGFR decreased significantly in the postoperative period (p< 0.001). Linear regression for eGFR value revealed that longer aortic cross-clamp time (ACCT) was associated with a greater decrease in eGFR (p= 0.046). Other variables included in the model, age (p= 0.128), gender (p= 0.358), RACHS (p= 0.865), body mass index (p= 0.862), prealbumin (p= 0.313), albumin (p= 0.806) and duration of cardiopulmonary bypass (p= 0.921) were found to be non-significant. Conclusion: While there was no relationship between eGFR and preoperative albumin/prealbumin levels in patients who underwent cardiac surgery due to congenital heart disease, longer ACCT was found to be associated with decreased eGFR.


2013 ◽  
Vol 146 (1) ◽  
pp. 146-152 ◽  
Author(s):  
Marnie L. Taylor ◽  
Fabio Carmona ◽  
Ravi R. Thiagarajan ◽  
Lauren Westgate ◽  
Michael A. Ferguson ◽  
...  

2016 ◽  
Vol 31 (suppl_1) ◽  
pp. i340-i340
Author(s):  
Anna Musielak ◽  
Magdalena Silska-Dittmar ◽  
Anna Benedyk ◽  
Danuta Ostalska-Nowicka ◽  
Jacek Zachwieja

2015 ◽  
Vol 6 (3) ◽  
pp. 401-406 ◽  
Author(s):  
Kurt D. Piggott ◽  
Meshal Soni ◽  
William M. Decampli ◽  
Jorge A. Ramirez ◽  
Dianna Holbein ◽  
...  

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