Long-term results following an anatomically based surgical technique for resection of colon cancer: a comparison with results from complete mesocolic excision

2016 ◽  
Vol 18 (7) ◽  
pp. 676-683 ◽  
Author(s):  
L. Bokey ◽  
P. H. Chapuis ◽  
C. Chan ◽  
P. Stewart ◽  
M. J. F. X. Rickard ◽  
...  

2017 ◽  
Vol 60 (7) ◽  
pp. 664-673 ◽  
Author(s):  
Masaaki Miyo ◽  
Ichiro Takemasa ◽  
Hiroyuki Ishihara ◽  
Taishi Hata ◽  
Tsunekazu Mizushima ◽  
...  


2020 ◽  
Vol 40 (3) ◽  
pp. 207-211
Author(s):  
Reem A. Alharbi ◽  
Riyadh Hakami ◽  
Khayal A. Alkhayal ◽  
Omar A. Al-Obeed ◽  
Thamer A. Bin Traiki ◽  
...  

ABSTRACT BACKGROUND: Data on long-term survival and recurrence of cancer after complete mesocolic excision (CME) for colon cancer has not been reported from our center and related to international data. OBJECTIVE: Describe overall and disease-free survival, survival by surgery site and stage, and recurrence rates after curative surgery. DESIGN: Retrospective chart review. SETTINGS: Academic tertiary care center. PATIENTS AND METHODS: The study included all patients who underwent either laparoscopic or open surgery for colon cancer with curative intent between 2001 and 2011. The colorectal database was reviewed for the following: demographic data, comorbidities, radiologic investigations, clinical stage, type of operation, complications, pathologic assessment, adjuvant treatment, recurrence and survival. Survival and recurrence rates were calculated, and survival curves were generated. MAIN OUTCOME MEASURES: 5-year overall survival, secondary endpoints were 5-year disease-free survival, survival by surgery site and stage, and recurrence rates. SAMPLE SIZE: 220. RESULTS: The mean (SD) age at diagnosis was 57 (13) years (CI 95%: 55-59 years). There were 112 males. Mean (SD) body mass index was 27.6 (5.7) kg/m 2 (CI 95%: 27-28). Pathological assessment revealed R0 (microscopically margin-negative) resection in 207 (94%). The overall 5-year survival and disease-free survival was 77.9% and 70%, respectively. The 5-year disease-free survival was 69% for the sigmoid/left colon and 69% for the right colon (difference statistically nonsignificant). Stages at the time of resection were stage 0 for 2 (0.01%) patients, stage I for 18 (8%), stage II for 92 (42%), stage III for 100 (46%), and stage IV for 6 (3%). The 5-year overall survival by stages I, II, III and IV was 94%, 80%, 75% and 50%, respectively (difference statistically non-significant). The overall 5-year recurrence rate was 23.4%. CONCLUSION: The outcomes of surgical treatment for colon cancer at our institution are equivalent to international sites. No difference was noted between left and right colon in terms of survival after CME. LIMITATIONS: Single center, retrospective, small sample size. CONFLICT OF INTEREST: None.



2016 ◽  
Vol 25 (3) ◽  
pp. 252-262 ◽  
Author(s):  
Nam Kyu Kim ◽  
Young Wan Kim ◽  
Yoon Dae Han ◽  
Min Soo Cho ◽  
Hyuk Hur ◽  
...  


Author(s):  
Kazuki Ueda ◽  
Koji Daito ◽  
Hokuto Ushijima ◽  
Yoshinori Yane ◽  
Yasumasa Yoshioka ◽  
...  

Abstract Background Complete mesocolic excision (CME) with central vascular ligation (CVL) for colon cancer is an essential procedure for improved oncologic outcomes after surgery. Laparoscopic surgery for splenic flexure colon cancer was recently adopted due to a greater understanding of surgical anatomy and improvements in surgical techniques and innovative surgical devices. Methods We retrospectively analyzed the data of patients with splenic flexure colon cancer who underwent laparoscopic CME with CVL at our institution between January 2005 and December 2017. Results Forty-five patients (4.8%) were enrolled in this study. Laparoscopic CME with CVL was successfully performed in all patients. The median operative time was 178 min, and the median estimated blood loss was 20 g. Perioperative complications developed in 6 patients (13.3%). The median postoperative hospital stay was 9 days. According to the pathological report, the median number of harvested lymph nodes was 15, and lymph node metastasis developed in 14 patients (31.1%). No metastasis was observed at the root of the middle colic artery or the inferior mesenteric artery. The median follow-up period was 49 months. The cumulative 5-year overall survival and disease-free survival rates were 85.9% and 84.7%, respectively. The cancer-specific survival rate in stage I-III patients was 92.7%. Recurrence was observed in 5 patients (11.1%), including three patients with peritoneal dissemination and two patients with distant metastasis. Conclusions Laparoscopic CME with CVL for splenic flexure colon cancer appears to be oncologically safe and feasible based on the short- and long-term outcomes in our study. However, it is careful to introduce this procedure to necessitate the anatomical understandings and surgeon’s skill. The appropriate indications must be established with more case registries because our experience is limited.



2018 ◽  
Vol 61 (9) ◽  
pp. 1063-1072 ◽  
Author(s):  
Claus Anders Bertelsen ◽  
Helene M. Larsen ◽  
Anders U. Neuenschwander ◽  
Søren Laurberg ◽  
Bent Kristensen ◽  
...  


Sign in / Sign up

Export Citation Format

Share Document