scholarly journals Quality of life in patients with resectable rectal cancer during the first 24 months following diagnosis

2020 ◽  
Vol 22 (12) ◽  
pp. 2028-2037
Author(s):  
S. Walming ◽  
D. Asplund ◽  
D. Bock ◽  
E. Gonzalez ◽  
J. Rosenberg ◽  
...  



2016 ◽  
Vol 7 (4) ◽  
pp. 303-319
Author(s):  
Dalia A. Abdelatief ◽  
Basma M. Khalil ◽  
Wafaa Kh. Ibrahem ◽  
Hatem M. Abdalla


Cancers ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 742
Author(s):  
Vincent Maurice Meyer ◽  
Richtje R Meuzelaar ◽  
Yvonne Schoenaker ◽  
Jan-Willem de Groot ◽  
Edwin de Boer ◽  
...  

Non operative management of complete clinical responders after neoadjuvant treatment for rectal cancer enjoys an increasing popularity because of the increased functional outcome results. Even a near complete response can evolve in a cCR, and therefore further delaying response assessment is accepted. However, up to 40% of patients will develop a regrowth and will eventually require delayed surgery. It is presently unknown if and to what extent quality of life of these patients is affected, compared to patients who undergo immediate surgery. Between January 2015-May 2020, 200 patients were treated with neoadjuvant therapy of whom 94 received TME surgery. Fifty-one (59%) of 87 alive patients returned the questionnaires: 33 patients who underwent immediate and 18 patients who underwent delayed surgery. Quality of life was measured through the QLQ-C30, QLQ-CR29, and Cancer Worry Scale questionnaires. Regret to participate in repeated response assessment protocol was assessed through the Decision Regret Scale. Exploratory factor analysis (EFA) and a ‘known groups comparison’ was performed to assess QLQ questionnaires validity in this sample. Higher mean physical function scores (89.2 vs. 77.6, p = 0.03) were observed in the immediate surgery group, which lost significance after correction for operation type (p = 0.25). Arousal for men was higher in the delayed surgery group (20.0 vs. 57.1, p = 0.02). There were no differences between surgical groups for the other questionnaire items. Worry for cancer was lower in the delayed surgery group (10.8 vs. 14.0, p = 0.21). Regret was very low (12–16%). EFA reproduced most QLQ C-30 and CR29 subscales with good internal consistency. Quality of life is not impaired in patients undergoing delayed TME surgery after neoadjuvant treatment for rectal cancer. Moreover, there is very low regret and no increase in worry for cancer. Therefore, from a quality of life perspective, this study supports a repeated response assessment strategy after CRTx for rectal carcinoma to identify all complete responders.



2004 ◽  
Vol 22 (2) ◽  
pp. 354-360 ◽  
Author(s):  
Philippe Rauch ◽  
Joelle Miny ◽  
Thierry Conroy ◽  
Lionel Neyton ◽  
Francis Guillemin

Purpose To identify factors affecting the quality of life (QoL) of disease-free survivors of rectal cancer. Patients and Methods One hundred twenty-one patients in complete remission more than 2 years after diagnosis were asked to complete three QoL questionnaires: the European Organization for Research and Treatment of Cancer (EORTC) QLQ-C30; its colorectal module, QLQ-CR38; and the Duke generic instrument. Results Patients reported less pain (P = .002) than did controls drawn from the general population. EORTC QLQ-C30 physical scores were also higher among rectal cancer survivors than in the general Norwegian or German population (P = .0005 and P = .002, respectively). Unexpectedly, stoma patients reported better social functioning than did nonstoma patients (P = .005), with less anxiety (P = .008) and higher self-esteem (P = .0002). In the present authors' experience, the QLQ-CR38 does not discriminate between these groups. Residual abdominal or pelvic pain and constipation had the most negative influence on QoL. Conclusion QoL is high among rectal cancer survivors, including stoma patients. Simultaneous use of several QoL questionnaires appears to have value in follow-up and in monitoring the effects of therapy. The impact of residual pain and constipation on long-term QoL should be considered when establishing a treatment regimen.



2016 ◽  
Vol 119 ◽  
pp. S112
Author(s):  
A.M. Couwenberg ◽  
J.P.M. Burbach ◽  
M. Van Vulpen ◽  
M.P.W. Intven ◽  
O. Reerink ◽  
...  


2016 ◽  
Vol 15 (3) ◽  
pp. e93-e99 ◽  
Author(s):  
Lisette M. Wiltink ◽  
Remi A. Nout ◽  
Jochem R.N. van der Voort van Zyp ◽  
Heleen M. Ceha ◽  
Marta Fiocco ◽  
...  


2002 ◽  
Vol 4 (1) ◽  
pp. 61-66 ◽  
Author(s):  
J. Camilleri-Brennan ◽  
R. J. C. Steele


2013 ◽  
Vol 105 (5) ◽  
pp. 255-261 ◽  
Author(s):  
Juan Ignacio Arraras ◽  
Javier Suárez ◽  
Fernando Arias-de-la-Vega ◽  
Ruth Vera ◽  
Berta Ibáñez ◽  
...  


Sign in / Sign up

Export Citation Format

Share Document