Editorial May 2021 issue of Colorectal Disease

2021 ◽  
Vol 23 (5) ◽  
pp. 1029-1029
Author(s):  
Felix Aigner
Keyword(s):  
Colorectal Disease

High iron diamine?alcian blue mucin profiles in benign, premalignant and malignant colorectal disease

1988 ◽  
Vol 13 (4) ◽  
pp. 399-411 ◽  
Author(s):  
D. C. ALLEN ◽  
N. S. CONNOLLY ◽  
J. D. BIGGART
Keyword(s):  
Alcian Blue ◽  
Colorectal Disease ◽  
High Iron

scholarly journals Fistula-Related Cancer in Crohn’s Disease: A Systematic Review

Cancers ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 1445
Author(s):  
Andromachi Kotsafti ◽  
Melania Scarpa ◽  
Imerio Angriman ◽  
Ignazio Castagliuolo ◽  
Antonino Caruso
Keyword(s):  
Systematic Review ◽  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Hpv Vaccination ◽  
Perianal Fistula ◽  
Hpv Infection ◽  
Poor Quality ◽  
Colorectal Disease ◽  
Small Series ◽  
Chron's Disease

Perianal fistulizing Crohn’s disease is a very disabling condition with poor quality of life. Patients with perianal fistulizing Crohn’s disease are also at risk of perianal fistula-related squamous cell carcinoma (SCC). Cancer arising at the site of a chronic perianal fistula is rare in patients with Crohn’s disease and there is a paucity of data regarding its incidence, diagnosis and management. A systematic review of the literature was undertaken using Medline, Embase, Pubmed, Cochrane and Web of Science. Several small series have described sporadic cases with perianal cancer in Crohn’s disease. The incidence rate of SCC related to perianal fistula was very low (<1%). Prognosis was poor. Colorectal disease, chronic perianal disease and HPV infection were possible risk factors. Fistula-related carcinoma in CD (Chron’s disease) can be very difficult to diagnose. Examination may be limited by pain, strictures and induration of the perianal tissues. HPV is an important risk factor with a particular carcinogenesis mechanism. MRI can help clinicians in diagnosis. Examination under anesthesia is highly recommended when findings, a change in symptoms, or simply long-standing disease in the perineum are present. Future studies are needed to understand the role of HPV vaccination in preventing fistula-related cancer.

scholarly journals State-of-the-art colorectal disease: postoperative ileus

2021 ◽  
Author(s):  
Nils P. Sommer ◽  
Reiner Schneider ◽  
Sven Wehner ◽  
Jörg C. Kalff ◽  
Tim O. Vilz
Keyword(s):  
Postoperative Ileus ◽  
Enhanced Recovery ◽  
Treatment Strategies ◽  
Colorectal Disease ◽  
Opioid Receptor Antagonists ◽  
Hospital Stays ◽  
Definition Of ◽  
Meta Analyses ◽  
Epidural Catheters ◽  
Prolonged Hospital

Abstract Purpose Postoperative Ileus (POI) remains an important complication for patients after abdominal surgery with an incidence of 10–27% representing an everyday issue for abdominal surgeons. It accounts for patients’ discomfort, increased morbidity, prolonged hospital stays, and a high economic burden. This review outlines the current understanding of POI pathophysiology and focuses on preventive treatments that have proven to be effective or at least show promising effects. Methods Pathophysiology and recommendations for POI treatment are summarized on the basis of a selective literature review. Results While a lot of therapies have been researched over the past decades, many of them failed to prove successful in meta-analyses. To date, there is no evidence-based treatment once POI has manifested. In the era of enhanced recovery after surgery or fast track regimes, a few approaches show a beneficial effect in preventing POI: multimodal, opioid-sparing analgesia with placement of epidural catheters or transverse abdominis plane block; μ-opioid-receptor antagonists; and goal-directed fluid therapy and in general the use of minimally invasive surgery. Conclusion The results of different studies are often contradictory, as a concise definition of POI and reliable surrogate endpoints are still absent. These will be needed to advance POI research and provide clinicians with consistent data to improve the treatment strategies.

General Practitioner Referral of Patients with Lower Gastrointestinal Symptoms

1988 ◽  
Vol 81 (2) ◽  
pp. 87-88 ◽  
Author(s):  
R G Springall ◽  
I P Todd
Keyword(s):  
General Practitioner ◽  
Gastrointestinal Symptoms ◽  
Accurate Diagnosis ◽  
Direct Access ◽  
Colorectal Disease ◽  
Rectal Examination ◽  
Low Incidence

Of 500 consecutive patients with symptoms of colorectal disease referred to a specialist hospital for outpatient assessment, 305 were studied. There was a low incidence of examination by the general practitioner; less than half the patients had a rectal examination and 31% had no examination at all. In cases where GPs made a diagnosis, this was correct in half, which both demonstrates the potential for dangerous misdiagnosis and confirms the fact that many anorectal conditions can be identified by the history alone. It is suggested that direct-access clinics in a colorectal unit would minimize delay in accurate diagnosis. The resource implications for such a system would be limited in terms of special investigations and additional clinic facilities.

Randomized controlled trials in colorectal disease; a review of recent trials

2008 ◽  
Vol 3 (1) ◽  
pp. 58-64
Author(s):  
B. E. Lovett ◽  
I. Taylor
Keyword(s):  
Randomized Controlled Trials ◽  
Colorectal Disease ◽  
Controlled Trials ◽  
Randomized Controlled

Commentary: What role do lasers play in the management of colorectal disease

1991 ◽  
pp. 116-119
Author(s):  
S. G. Bown
Keyword(s):  
Colorectal Disease

Surgical Management of Benign and Malignant Colorectal Disease in the Immunocompromised Patient

2017 ◽  
Author(s):  
Cindy Kin ◽  
Amy Lightner ◽  
Mark Welton
Keyword(s):  
Preoperative Evaluation ◽  
Disease Process ◽  
Underlying Disease ◽  
Colorectal Disease ◽  
Immunosuppressed Patient ◽  
Neutropenic Enterocolitis ◽  
Anal Squamous Cell Carcinoma ◽  
Benign Colorectal Disease ◽  
Immunosuppressed Patients ◽  
Inflammatory Bowel

Patients who are immunosuppressed either due to an underlying disease process or medications to treat a disease require important perioperative considerations. Preoperative evaluation mandates a higher index of suspicion for pathology given that peritoneal and systemic markers of illness may be masked. Intraoperatively, consideration should be given for diversion more frequently than in a nonimmunosuppressed patient. Postoperatively, patients should be managed in a multidisciplinary fashion. This review largely focuses on the immunosuppressive mediations used for the treatment of inflammatory bowel disease, benign colorectal disease in an immunosuppressed patient, and colorectal malignancies in immunosuppressed patients to highlight important considerations for this patient population. This review contains 4 figures, 5 tables, and 78 references. Key words: anal squamous cell carcinoma, appendicitis versus typhlitis, biologic therapy, corticosteroids, human papillomavirus, immunosuppression, neutropenic enterocolitis 

Colorectal Disease

2010 ◽  
Keyword(s):  
Colorectal Disease

Imaging in Colorectal Disease

2016 ◽  
pp. 997-997
Author(s):  
Poonam Narang
Keyword(s):  
Colorectal Disease
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