Comparison of heated humidified high flow nasal cannula and nasal continuous positive airway pressure after surfactant administration in preterm neonates with respiratory distress syndrome

2020 ◽  
Vol 14 (8) ◽  
pp. 740-747
Author(s):  
Zahra Akbarian‐rad ◽  
Avishan Mohammadi ◽  
Soraya Khafri ◽  
Mousa Ahmadpour‐kacho ◽  
Yadollah Zahed‐pasha ◽  
...  
Keyword(s):  
Continuous Positive Airway Pressure ◽  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Airway Pressure ◽  
Distress Syndrome ◽  
Positive Airway Pressure ◽  
High Flow ◽  
Preterm Neonates ◽  
High Flow Nasal Cannula ◽  
Surfactant Administration

scholarly journals Continuous Positive Airway Pressure or High Flow Nasal Cannula for Respiratory Distress Syndrome: a Randomized Control Trail among Premature Infants

2019 ◽  
Author(s):  
Tahereh Esmaeilnia Shirvani ◽  
Fatemeh Sadat Nayeri ◽  
Mamak Shariat ◽  
Nikoo Nik Nafas ◽  
Seyyed Reza Mirjalili ◽  
...  
Keyword(s):  
Continuous Positive Airway Pressure ◽  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Premature Infants ◽  
Airway Pressure ◽  
Distress Syndrome ◽  
Positive Airway Pressure ◽  
High Flow ◽  
High Flow Nasal Cannula ◽  
Randomized Control

Abstract Background Respiratory distress syndrome (RDS) is a life-threatening pulmonary disorder which mainly related to the premature infants. This study was conducted to evaluate Continuous Positive Airway Pressure (CPAP) and High Flow Nasal Cannula (HFNC) intervention effectiveness among premature infants with RDS. Methods Overall, 60 preterm infants with RDS at Valiasr Hospital, Tehran, during 2018 in this randomized control trail participated as CPAP and HFNC groups’ treatment. CPAP group received the nose with a peep of 4-6 centimeters from birth and continued to improve respiratory distress and the need for oxygen (O2). HFNC group received hot and humid flowing 2 to 5 liters/min in nose cannula, until respiratory distress and O2 needing to be resolved. Short clinical outcomes were compared between two groups. Data were analyzed by SPSS version 16 using t-test and logistic regression statistical tests at 95% significant level. Results There were no significant differences in Pneumothorax, PDA, chronic lung disease, surfactant injection, tracheal intubation, death, NEC, number of full feeding days, duration of hospitalization, and number of oxygen therapy days between the both CPAP and HFNC groups. Conclusions CPAP and HFNC techniques have the same efficacy in confronting RDS in neonates and there is no difference between the two techniques in terms of in-hospital clinical outcomes. However, considering the same efficacy of two methods and less invasive of HFNC compared with CPAP, we concluded this method can be recommended for the improvement of respiratory distress in newborns. Trial Registration Iranian Registry of Clinical Trials identifier IRCT20190623043988N1 Registered 2019-07-05.

Sign in / Sign up

Export Citation Format

Share Document