CD4 / CD8 double‐negative early‐stage mycosis fungoides with CD30 expression

Author(s):  
Uri Shon ◽  
Dea Kwan Yun ◽  
Gi Hyun Seong ◽  
Byung Cheol Park ◽  
Myung Hwa Kim ◽  
...  
2021 ◽  
pp. 256-261
Author(s):  
Monira Abdullah Alnasser ◽  
Nour Marwan AlKhawajah ◽  
Nada Ghazi AlQadri ◽  
Asem Mustafa Shadid ◽  
Fahad M. Alsaif

Cutaneous T-cell lymphoma (CTCL) describes a group of lymphoproliferative disorders characterized by localization of neoplastic T lymphocytes to the skin. Mycosis fungoides (MF) represents the most common type of CTCL and accounts for ∼60% of all primary cutaneous lymphomas. Apart from the classic type of MF, many clinical and histopathologic variants have been described. The malignant lymphocytes in MF are usually CD3, CD4 and CD45RO positive and CD8 negative. An unusual immunohistochemical profile of a CD4-negative and CD8-positive mature T-cell phenotype has been reported in a minority of patients; up to 20% of early-stage MF demonstrates a CD8-positive phenotype. There are only a few cases of a double-negative CD4/CD8 MF phenotype reported in the literature. We present the case of a 60-year-old male presenting a double-negative CD4/CD8 MF phenotype.


Author(s):  
A. Lallas ◽  
Z. Apalla ◽  
I. Lefaki ◽  
T. Tzellos ◽  
A. Karatolias ◽  
...  

2017 ◽  
Vol 137 (5) ◽  
pp. S43
Author(s):  
A. Yuki ◽  
R. Abe ◽  
H. Fujikawa ◽  
R. Hayashi ◽  
E. Homma ◽  
...  

2011 ◽  
Vol 23 (4) ◽  
pp. 474 ◽  
Author(s):  
Min Soo Jang ◽  
Jae Woo Baek ◽  
Jong Bin Park ◽  
Dong Young Kang ◽  
Jin Seuk Kang ◽  
...  

2019 ◽  
Vol 26 (2) ◽  
pp. 408-418 ◽  
Author(s):  
John T. O'Malley ◽  
Adele de Masson ◽  
Elizabeth L. Lowry ◽  
Anita Giobbie-Hurder ◽  
Nicole R. LeBoeuf ◽  
...  

2017 ◽  
Vol 97 (8) ◽  
pp. 976-978
Author(s):  
I Wieser ◽  
A Huean ◽  
A Bush ◽  
B Dabaja ◽  
M Duvic

2005 ◽  
Vol 30 (4) ◽  
pp. 376-378 ◽  
Author(s):  
S. Z. Ghodsi ◽  
Z. Hallaji ◽  
K. Balighi ◽  
F. Safar ◽  
C. Chams-Davatchi

Author(s):  
Joshua M. Brady

A clinical decision report using Vieyra-Garcia P, Fink-Puches R, Porkert S, et al. Evaluation of Low-Dose, Low-Frequency Oral Psoralen–UV-A Treatment With or Without Maintenance on Early-Stage Mycosis Fungoides. JAMA Dermatology. 2019;155(5):538. https://doi.org/10.1001/jamadermatol.2018.5905 for a patient weighing whether to continue treatment in light of socioeconomic circumstances.


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