Microstrip band-stop filter based on double negative metamaterial

In this work, we present a novel miniature band stop filter based on double negative metamaterial, this circuit is designed on a low-cost substrate FR-4 of relative permittivity 4.4 and low tangential losses 0.002. The proposed filter has a compact and miniature size of 15 mm in length and 12mm in width without the 50 Ω feed lines. The resonator was studied and analyzed with a view to achieving a band-stop behavior around its resonant frequency. The band-stop characteristics are obtained by implementing the metamaterial resonator on the final structure. The obtained results show that this microstrip filter achieves fractional bandwidth of 40% at 2 GHz. Furthermore, excellent transmission quality and good attenuation are achieved. This filter is an adequate solution for global system for mobile communications (GSM).

Study on the high birefringence and low confinement loss terahertz fiber based on the combination of double negative curvature and nested claddings

A novel double negative curvature nested fiber structure is designed by adding extra circular cladding tubes to enhance the birefringence and reduce the confinement loss. The fiber structure is composed of eight circular cladding tubes and two semi-elliptical nested tubes. The transmission performances of terahertz fiber, including birefringence, confinement loss, dispersion and effective mode field area, are studied by changing the parameters of cladding tubes. In the frequency range of 1.75 - 2.6 THz, the broad bandwidth of 850 GHz with high birefringence (above 10-4) can be achieved. The confinement loss of y-polarization mode with the frequency of 2.575 THz can be as low as 0.00231 dB/cm. The waveguide dispersion coefficient is between ±0.188 ps/(THz•cm) in the frequency range of 2.0 - 2.475 THz. The maximum effective mode field area of x- polarization mode is 2.618×10-6 m2 at 2.6 THz.

Cut-off value of D. pteronyssinus specific IgE in double negative patients Der p 1 and Der p 2 and its clinical repercussion

Accessibility to more precise diagnostic techniques such as component resolved diagnostics (CRD), provides us with an important advance in diagnostic aspects as well as treatment. The subject of this study aims to better understand the profiles of sensitization to Der p 1, Der p 2 and Der p 23 and to know to what extent their use could help us in optimizing the decision-making for their treatment with Specific Immunotherapy. Cross-sectional study of subjects older than 5 years, diagnosed with allergy to HDM using skin prick test and sIgE, with symptoms of rhinitis and/or asthma. Total and specific IgE was determined to D. pteronyssinus, nDer p 1, rDer p 2 and rDer p 23 using ImmunoCAP. 240 patients were recruited (97.1% rhinitis and 46.25% rhinitis and asthma). Four different phenotypes were observed: positive or negative for sIgE nDer p 1 and/or IgE rDer p 2. 17% of these patients sIgE were double negative for Der p 1 and Der p 2 (increasing with age and with significantly lower sIgE levels than the rest of the groups). Using ROC curves, value less than 2.18 KUA/L for D. pteronyssinus sIgE gave us a sensitivity and specificity of 0.882 and 0.985, respectively, to double negative IgE nDer p 1 and IgE rDer p 2 group. Despite positive SPT and sIgE to D. pteronyssinus, 17% of the studied population is IgE nDer p 1 and IgE rDer p 2 double negative, with a cut-off value of 2.18 KU/L, which is very relevant for taking of decisions in prescription of AIT. The double positive population sIgE nDer p 1 and IgE rDer p 2 is associated with asthma compared to the other groups and this does not seem to be influenced by IgE rDer p 23.

Patch Antenna Based on MUC for Wi-Fi and 5G

This communication reported the patch antenna working at Wi-Fi and 5G bands. To acquire compactness the side lengths of the patch are taken based on upper-frequency band (3.3 GHz). Dual-band operation (lower resonating band) is realized by loading the Mushroom Unit Cell (MUC) along the bottom right corner of the patch. To obtain Circular Polarization (CP) at the 5G band the conventional patch is modified with fractal boundary. This blend of the Double Negative Transmission Lines metamaterials (DNG TL), as well as fractal concepts yielded good compactness suitable for ultra-thin portable gadgets. Measured results have good correlation with simulated data from HFSS. The obtained bandwidths at the lower and upper bands are 2.51 % and 6.23 % when the Poly fractal curves are introduced. CP bandwidth of the proposed antenna at 5G band obtained from the measured data is 2.35 % which is the highest to the best of authors' knowledge for this type of thin antennas.

Distinct CD4−CD8− (Double-Negative) Memory T-Cell Subpopulations Are Associated With Indeterminate and Cardiac Clinical Forms of Chagas Disease

CD4−CD8− (double-negative, DN) T cells are critical orchestrators of the cytokine network associated with the pathogenic inflammatory response in one of the deadliest cardiomyopathies known, Chagas heart disease, which is caused by Trypanosoma cruzi infection. Here, studying the distribution, activation status, and cytokine expression of memory DN T-cell subpopulations in Chagas disease patients without cardiac involvement (indeterminate form—IND) or with Chagas cardiomyopathy (CARD), we report that while IND patients displayed a higher frequency of central memory, CARD had a high frequency of effector memory DN T cells. In addition, central memory DN T cells from IND displayed a balanced cytokine profile, characterized by the concomitant expression of IFN-γ and IL-10, which was not observed in effector memory DN T cells from CARD. Supporting potential clinical relevance, we found that the frequency of central memory DN T cells was associated with indicators of better ventricular function, while the frequency of effector memory DN T cells was not. Importantly, decreasing CD1d-mediated activation of DN T cells led to an increase in IL-10 expression by effector memory DN T cells from CARD, restoring a balanced profile similar to that observed in the protective central memory DN T cells. Targeting the activation of effector memory DN T cells may emerge as a strategy to control inflammation in Chagas cardiomyopathy and potentially in other inflammatory diseases where these cells play a key role.

Metamaterial based on an inverse double V loaded complementary square split ring resonator for radar and Wi-Fi applications

In this research paper, an inverse double V loaded complementary square split ring resonator based double negative (DNG) metamaterial has been developed and examined numerically and experimentally. The electromagnetic (EM) properties of the proposed inverse double V-structure were calculated using computer simulation technology (CST-2019) and the finite integration technique (FIT). The designed metamaterial provides three resonance frequencies are 2.86, 5, and 8.30 GHz, covering S-, C-, and X-bands. The total size of the recommended unit cell is 8 $$\times$$ × 8 $$\times$$ × 1.524 mm3, and a high effective medium ratio (EMR) value of 13.11 was found from it. The − 10 dB bandwidths of this structure are 2.80 to 2.91, 4.76 to 5.17, and 8.05 to 8.42 GHz. The proposed structure's novelty is its small size, simple resonator structure, which provides double negative characteristics, high EMR, maximum coverage band, and required resonance frequencies. Wi-Fi network speeds are generally faster when frequencies in the 5 GHz band are used. Since the proposed structure provides a 5 GHz frequency band, hence the suggested metamaterial can be used in Wi-Fi for high bandwidth and high-speed applications. The marine radars operate in X-band, and weather radar works in S-band. Since the designed cell provides two more resonance frequencies, i.e., 2.86 GHz (S-band) and 8.30 GHz (X-band), the proposed metamaterial could be used in weather radar and marine radar. The design process and various parametric studies have been analyzed in this article. The equivalent circuit is authenticated using the advanced design system (ADS) software compared with CST simulated result. The surface current, E-field, and H-field distributions have also been analyzed. Different types of array structure, i.e., 1 $$\times$$ × 2, 2 $$\times$$ × 2, 3 $$\times$$ × 3, 4 $$\times$$ × 4, and 20 $$\times$$ × 25 is examined and validated by the measured result. The simulated and measured outcome is an excellent agreement for the inverse double V loaded CSSRR unit cell and array. We showed the overall performance of the suggested structure is better than the other structures mentioned in the paper. Since the recommended metamaterial unit cell size is small, provides desired resonance frequency, gives a large frequency band and high EMR value; hence the suggested metamaterial can be highly applicable for Radar and Wi-Fi.