scholarly journals Myocardial work and left ventricular contractile reserve during stress echocardiography: An angiographic validation

2021 ◽  
Author(s):  
Natalie F. A. Edwards ◽  
Gregory M. Scalia ◽  
Anthony Putrino ◽  
Vinesh Appadurai ◽  
Surendran Sabapathy ◽  
...  

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
D Morrone ◽  
R Arbucci ◽  
K Wierzbowska-Drabik ◽  
Q Ciampi ◽  
J Peteiro ◽  
...  

Abstract Background An enlarged left atrial volume index (LAVI) at rest mirrors increased LA pressure and/or impairment of LA function. A cardiovascular stress may acutely modify LAVI within minutes. Purpose To assess the feasibility and functional correlates of LAVI-stress echocardiography (SE) Methods Out of 514 subjects referred to 10 quality-controlled labs, LAVI-SE was completed in 490 (359 male, age 67±12 yrs, ejection fraction 60±10%) with suspected or known chronic coronary syndromes (n=462) or asymptomatic controls (n=28). The utilized stress was exercise in 177, vasodilator in 167, dobutamine in 146. LAVI was measured with the biplane disk summation method. SE was performed with the ABCDE protocol. In a single center sub-study in 50 subjects, including 28 controls and 22 patients, also peak longitudinal atrial strain (PALS, %) was measured as an index of LA reservoir function. Results The intra-observer and inter-observer LAVI variability were 5% and 8%, respectively. Δ-LAVI changes (stress-rest) were negatively correlated with resting LAVI (r=−0.271, p<0.001), heart rate reserve (r=−0.239, p<0.001), and Δ-PALS (n=50, r=−0.374, p=0.007).LAVI-dilators were defined as those with stress-rest increase ≥6.8 ml/m2, a cutoff derived from a calculated reference change value above the biological, analytical and observer variability of LAVI. LAVI dilation (see figure) occurred in 56 patients (11%). At multivariable logistic regression analysis, B-lines ≥2 (OR: 2.586, 95% CI =1.1293–5.169, p=0.007) and abnormal left ventricular contractile reserve (OR: 2.207, 95% CI=1.111–4.386, p=0.024) were associated with LAVI dilation. Conclusion LAVI-SE is feasible, with high success rate and low variability, in patients with chronic coronary syndromes. A wet (increased B-lines) and weak (reduced LV contractile reserve and LA reservoir function) heart frequently portends LAVI dilation during stress. Figure 1 Funding Acknowledgement Type of funding source: None



2012 ◽  
Vol 31 (4) ◽  
pp. 287-293
Author(s):  
Marcia M. Barbosa ◽  
Cláudia M.V. Freire ◽  
Bruno Ramos Nascimento ◽  
Carlos E. Rochitte ◽  
Marly C. Silva ◽  
...  




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