Comparison of the regenerative effect of adipose-derived stem cells, fibrin glue scaffold, and autologous bone graft in experimental mandibular defect in rabbit

2018 ◽  
Vol 34 (6) ◽  
pp. 413-420 ◽  
Author(s):  
Davood Mehrabani ◽  
Azizollah Khodakaram-Tafti ◽  
Hanieh Shaterzadeh-Yazdi ◽  
Barbad Zamiri ◽  
Mahsa Omidi
Keyword(s):  
Stem Cells ◽  
Bone Graft ◽  
Fibrin Glue ◽  
Autologous Bone Graft ◽  
Adipose Derived Stem Cells ◽  
Regenerative Effect ◽  
Mandibular Defect ◽  
Autologous Bone

scholarly journals Revitalization of frozen autologous bone graft using adipose-derived stem cells

2020 ◽  
Vol 6 (2) ◽  
Author(s):  
Aoki Y ◽  
Yamamoto N ◽  
Hayashi K ◽  
Sugimoto N ◽  
Kimura H ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Graft ◽  
Autologous Bone Graft ◽  
Adipose Derived Stem Cells ◽  
Autologous Bone

THA conversion rate comparing decompression alone, with autologous bone graft or stem cells in osteonecrosis

2017 ◽  
Vol 28 (2) ◽  
pp. 189-193 ◽  
Author(s):  
Francisco J. Nally ◽  
Gerardo Zanotti ◽  
Martín A. Buttaro ◽  
Fernando D. Dilernia ◽  
Ignacio G. Mansilla ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Graft ◽  
Conversion Rate ◽  
Core Decompression ◽  
Corticosteroid Treatment ◽  
Autologous Bone Graft ◽  
Equal Treatment ◽  
Rank Test ◽  
Survivorship Analysis ◽  
Autologous Bone

Introduction: Core decompression (CD) with or without the addition of autologous bone graft (CDBG) is currently the most widely accepted treatment for hip osteonecrosis in stages of pre-collapse. The use of bone marrow mesenchymal stem cells (CDSC) is emerging as a promising biological alternative. We sought to determine the total hip arthroplasty (THA) conversion rate for patients treated with CD, CDBG or CDSC. Material and methods: Between 1996 and 2012, 97 cases were evaluated in 72 patients: 47 CD cases, 34 CDGB cases and 16 CDSC cases. The mean age was 39 (20-63) years, 25 bilateral, 19 female and 53 male, 14 Ficat 1 and 83 Ficat 2. Bilateral cases with asymmetric stage and equal treatment were excluded. Results: Conversion rate to THA was 44% for the CD group (21/47) at an average of 77 (24-324) months; 50% for the CDBG group (17/34) at an average of 34 (24-240) months and 50% for the CDSC group (8/16) at an average of 48 (24-72) months (p = 0.619). Log Rank test for survivorship analysis was not significant (p = 0.2011). Immunodeficiency or corticosteroid treatment history was associated with 16/47 of the CD group, 7/34 in the CDBG group and 1/16 in the CDSC group. Trauma was associated with 2/47 of the CD group, 5/34 of the CDBG group and none of the CDSC group. Hazard ratio considering risk factors was not significant (p = 0.252). Conclusions: In these series of cases including patients with pre-collapse osteonecrosis, we observed non-significant results regarding rate of conversion to THA with CD, CDBG or CDSC at an average of 5.5 years.

Osteoplasty in Disseminated Calvarial Defects Treated with Autologous Adipose-Derived Stem Cells and Autologous Fibrin Glue: Case Report

Skull Base ◽  
2005 ◽  
Vol 15 (S 2) ◽  
Author(s):  
Stefan Lendeckel ◽  
A. Jödicke ◽  
P. Christophis ◽  
K. Heidinger ◽  
H.-P. Howaldt
Keyword(s):  
Stem Cells ◽  
Case Report ◽  
Fibrin Glue ◽  
Adipose Derived Stem Cells ◽  
Autologous Fibrin Glue ◽  
Calvarial Defects

Combining Microfractures, Autologous Bone Graft, and Autologous Matrix-Induced Chondrogenesis for the Treatment of Juvenile Osteochondral Talar Lesions

2017 ◽  
Vol 38 (5) ◽  
pp. 485-495 ◽  
Author(s):  
Riccardo D’Ambrosi ◽  
Camilla Maccario ◽  
Chiara Ursino ◽  
Nicola Serra ◽  
Federico Giuseppe Usuelli
Keyword(s):  
Bone Graft ◽  
Repeated Measures ◽  
Osteochondral Lesion ◽  
Young Patients ◽  
Case Series ◽  
Autologous Bone Graft ◽  
Lesion Size ◽  
Level Of Evidence ◽  
Significant Difference ◽  
Autologous Bone

Background: The purpose of this study was to evaluate the clinical and radiologic outcomes of patients younger than 20 years, treated with the arthroscopic-talus autologous matrix-induced chondrogenesis (AT-AMIC) technique and autologous bone graft for osteochondral lesion of the talus (OLT). Methods: Eleven patients under 20 years (range 13.3-20.0) underwent the AT-AMIC procedure and autologous bone graft for OLTs. Patients were evaluated preoperatively (T0) and at 6 (T1), 12 (T2), and 24 (T3) months postoperatively, using the American Orthopaedic Foot & Ankle Society Ankle and Hindfoot (AOFAS) score, the visual analog scale and the SF-12 respectively in its Mental and Physical Component Scores. Radiologic assessment included computed tomographic (CT) scan, magnetic resonance imaging (MRI) and intraoperative measurement of the lesion. A multivariate statistical analysis was performed. Results: Mean lesion size measured during surgery was 1.1 cm3 ± 0.5 cm3. We found a significant difference in clinical and radiologic parameters with analysis of variance for repeated measures ( P < .001). All clinical scores significantly improved ( P < .05) from T0 to T3. Lesion area significantly reduced from 119.1 ± 29.1 mm2 preoperatively to 77.9 ± 15.8 mm2 ( P < .05) at final follow-up as assessed by CT, and from 132.2 ± 31.3 mm2 to 85.3 ± 14.5 mm2 ( P < .05) as assessed by MRI. Moreover, we noted an important correlation between intraoperative size of the lesion and body mass index (BMI) ( P = .011). Conclusions: The technique can be considered safe and effective with early good results in young patients. Moreover, we demonstrated a significant correlation between BMI and lesion size and a significant impact of OLTs on quality of life. Level of Evidence: Level IV, retrospective case series.

Role of Autologous Bone Graft in the Surgical Treatment of Atrophic Nonunion of Midshaft Clavicular Fractures

Orthopedics ◽  
2012 ◽  
Author(s):  
Hui-Kuang Huang ◽  
Chao-Ching Chiang ◽  
Yu-Ping Su ◽  
Chi-Kuang Feng ◽  
Fang-Yao Chiu ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Bone Graft ◽  
Autologous Bone Graft ◽  
Autologous Bone ◽  
Atrophic Nonunion

Reconstruction of the glenoid using autologous bone-graft and the SMR Axioma TT metal-backed prosthesis

2018 ◽  
Vol 100-B (12) ◽  
pp. 1609-1617 ◽  
Author(s):  
A. M. Malhas ◽  
J. Granville-Chapman ◽  
P. M. Robinson ◽  
S. Brookes-Fazakerley ◽  
M. Walton ◽  
...  
Keyword(s):  
Bone Graft ◽  
Reliable Method ◽  
Titanium Surface ◽  
Bone Defects ◽  
Autologous Bone Graft ◽  
Short Term ◽  
Bone Deficiency ◽  
Autologous Bone ◽  
Shoulder Arthroplasties

Aims We present our experience of using a metal-backed prosthesis and autologous bone graft to treat gross glenoid bone deficiency. Patients and Methods A prospective cohort study of the first 45 shoulder arthroplasties using the SMR Axioma Trabecular Titanium (TT) metal-backed glenoid with autologous bone graft. Between May 2013 and December 2014, 45 shoulder arthroplasties were carried out in 44 patients with a mean age of 64 years (35 to 89). The indications were 23 complex primary arthroplasties, 12 to revise a hemiarthroplasty or resurfacing, five for aseptic loosening of the glenoid, and five for infection. Results Of the 45 patients, 16 had anatomical shoulder arthroplasties (ASA) and 29 had reverse shoulder arthroplasties (RSA). Postoperatively, 43/45 patients had a CT scan. In 41 of 43 patients (95%), the glenoid peg achieved > 50% integration. In 40 of 43 cases (93%), the graft was fully or partially integrated. There were seven revisions (16%) but only four (9%) required a change of baseplate. Four (25%) of the 16 ASAs were revised for instability or cuff failure. At two-year radiological follow-up, five of the 41 cases (11%) showed some evidence of lucent lines. Conclusion The use of a metal baseplate with a trabecular titanium surface in conjunction with autologous bone graft is a reliable method of addressing glenoid bone defects in primary and revision RSA setting in the short term. ASAs have a higher rate of complications with this technique.

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