Blood oxygenation level dependent signal and neuronal adaptation to optogenetic and sensory stimulation in somatosensory cortex in awake animals

2016 ◽  
Vol 44 (9) ◽  
pp. 2722-2729 ◽  
Author(s):  
Daniil P. Aksenov ◽  
Limin Li ◽  
Michael J. Miller ◽  
Alice M. Wyrwicz
2015 ◽  
Vol 26 (6) ◽  
pp. 647-653 ◽  
Author(s):  
Carsten M. Klingner ◽  
Stefan Brodoehl ◽  
Otto W. Witte

AbstractIn recent years, multiple studies have shown task-induced negative blood-oxygenation-level-dependent responses (NBRs) in multiple brain regions in humans and animals. Converging evidence suggests that task-induced NBRs can be interpreted in terms of decreased neuronal activity. However, the vascular and metabolic dynamics and functional importance of the NBR are highly debated. Here, we review studies investigating the origin and functional importance of the NBR, with special attention to the somatosensory cortex.


2005 ◽  
Vol 21 (4) ◽  
pp. 489-494 ◽  
Author(s):  
Karsten Müller ◽  
Jane Neumann ◽  
Gabriele Lohmann ◽  
Toralf Mildner ◽  
D. Yves von Cramon

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