Hydrocephalus due to marked enlargement of spinal roots in a patient with chronic inflammatory demyelinating polyradiculoneuropathy

2020 ◽  
Vol 27 (11) ◽  
pp. 2385-2388
Author(s):  
A. Iwasaki ◽  
N. Kokubun ◽  
K. Funakoshi ◽  
K. Hirata ◽  
K. Suzuki
Keyword(s):  
Chronic Inflammatory Demyelinating Polyradiculoneuropathy ◽  
Spinal Roots

scholarly journals Chronic inflammatory demyelinating polyradiculoneuropathy: two cases with cervical spinal cord compression

2005 ◽  
Vol 63 (3a) ◽  
pp. 666-669 ◽  
Author(s):  
Marcos R.G. de Freitas ◽  
Osvaldo J.M. Nascimento ◽  
Cristiane N. Soares ◽  
Adriana Rocha Brito ◽  
Romeu Cortes Domingues
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Compression ◽  
Cervical Spinal Cord ◽  
Cord Compression ◽  
Spinal Nerve ◽  
Chronic Inflammatory Demyelinating Polyradiculoneuropathy ◽  
Lower Limbs ◽  
Peripheral Nerve Disorder ◽  
Spinal Roots ◽  
Spinal Cord Compression Syndrome

Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a peripheral nerve disorder probably due to an immunological disturb. It evolves either in a steadily progressive or in a relapsing and fluctuating course. Weakness is mainly in the lower limbs proximally and distally. The electromyography is demyelinating. The cerebral spinal fluid protein is most of times elevated. Sometimes enlarged nerves are found. There are few cases described with spinal cord compression due to hypertrophic spinal nerve roots. Two patients (females, 66 and 67 years old) with diagnosis of a long standing CIDP are described. In the first one, the evolution was characterized by remission and relapsing course. The second patient had a chronic and progressive course. These patients presented after a long evolution a cervical spinal cord compression syndrome due to hypertrophic cervical roots. Neurologists must be aware of the possibility of development of spinal cord compression by enlarged spinal roots in patients with a long standing CIDP.

Human Neurofibromas in Co-Culture with Mouse Neurons

1982 ◽  
Vol 40 ◽  
pp. 194-195
Author(s):  
R.L. Martuza ◽  
T. Liszczak ◽  
A. Okun ◽  
T-Y Wang
Keyword(s):  
Schwann Cell ◽  
Schwann Cells ◽  
Genetic Disorder ◽  
Cranial Nerves ◽  
Sympathetic Nerves ◽  
Acoustic Neuromas ◽  
Spinal Roots ◽  
Neural Crest Origin ◽  
Multiple Abnormalities ◽  
Other Neoplasms

Neurofibromatosis (NF) is an autosomal dominant genetic disorder with a prevalence of 1/3,000 births. The NF mutation causes multiple abnormalities of various cells of neural crest origin. Schwann cell tumors (neurofibromas, acoustic neuromas) are the most common feature of neurofibromatosis although meningiomas, gliomas, and other neoplasms may be seen. The schwann cell tumors commonly develop from the schwann cells associated with sensory or sympathetic nerves or their ganglia. Schwann cell tumors on ventral spinal roots or motor cranial nerves are much less common. Since the sensory neuron membrane is known to contain a mitogenic factor for schwann cells, we have postulated that neurofibromatosis may be due to an abnormal interaction between the nerve and the schwann cell and that this interaction may be hormonally modulated. To test this possibility a system has been developed in which an enriched schwannoma cell culture can be obtained and co-cultured with pure neurons.

Characterization of Neurofibromas of the Skin and Spinal Roots in a Mouse Model

2007 ◽  
Author(s):  
Yuan Zhu
Keyword(s):  
Mouse Model ◽  
Spinal Roots

Characterization of Neurofibromas of the Skin and Spinal Roots in a Mouse Model

2008 ◽  
Author(s):  
Yuan Zhu
Keyword(s):  
Mouse Model ◽  
Spinal Roots
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