The risk of Stevens‐Johnson syndrome and toxic epidermal necrolysis in new users of antiepileptic drugs: Comment on data sparsity

Epilepsia ◽  
2018 ◽  
Vol 59 (5) ◽  
pp. 1083-1084 ◽  
Author(s):  
Saeid Safiri ◽  
Ahad Ashrafi‐Asgarabad
Keyword(s):  
Toxic Epidermal Necrolysis ◽  
Antiepileptic Drugs ◽  
Stevens Johnson Syndrome ◽  
Data Sparsity ◽  
Johnson Syndrome

Response: The risk of Stevens‐Johnson syndrome and toxic epidermal necrolysis in new users of antiepileptic drugs: Comment on data sparsity

Epilepsia ◽  
2018 ◽  
Vol 59 (5) ◽  
pp. 1084-1085 ◽  
Author(s):  
Noel Frey ◽  
Michael Bodmer ◽  
Andreas Bircher ◽  
Stephan Rüegg ◽  
Susan S. Jick ◽  
...  
Keyword(s):  
Toxic Epidermal Necrolysis ◽  
Antiepileptic Drugs ◽  
Stevens Johnson Syndrome ◽  
Data Sparsity ◽  
Johnson Syndrome

scholarly journals Stevens-Johnson syndrome induced by phenytoin: a case report

2016 ◽  
Vol 6 (1) ◽  
pp. 208
Author(s):  
Lalkota Prakash Bhanu ◽  
Kumara Swamy M. ◽  
Mohammed Nasiruddin ◽  
Naveen H. D. ◽  
Rajesh Venkataraman
Keyword(s):  
Adverse Reaction ◽  
Case Report ◽  
Toxic Epidermal Necrolysis ◽  
Antiepileptic Drugs ◽  
Stevens Johnson Syndrome ◽  
Drug Reactions ◽  
Cutaneous Adverse Reaction ◽  
Johnson Syndrome ◽  
Life Threatening ◽  
Grade 3

Stevens-Johnson syndrome (SJS) and Toxic epidermal necrolysis (TEN) are rare (one to two per 10,00,00 population per year) but life threatening adverse drug reactions. Antiepileptic drugs-induced Stevens-Johnson syndrome (SJS) is a life-threatening severe cutaneous adverse reaction, amongst anti-epileptics; carbamazepine and phenytoin are the major culprits. We report here a case of SJS due to phenytoin (CTC vs 2 Grade 3).

TOXIC EPIDERMOLYSIS CAUSED BY ANTIEPILEPTIC DRUGS: CLINICAL OBSERVATIONS

2021 ◽  
Vol 100 (1) ◽  
pp. 282-287
Author(s):  
M.A. Ufimtseva ◽  
◽  
M.A. Zakharov ◽  
O.Yu. Averyanov ◽  
O.V. Kozhevnikova ◽  
...  
Keyword(s):  
Adverse Drug Reaction ◽  
Drug Reaction ◽  
Toxic Epidermal Necrolysis ◽  
Antiepileptic Drugs ◽  
Stevens Johnson Syndrome ◽  
International Literature ◽  
Emergency Medical Care ◽  
Clinical Observations ◽  
Johnson Syndrome

Toxic epidermal necrolysis (Lyell's syndrome) and Stevens–Johnson syndrome are severe types of toxicodermia and require emergency medical care. The pathophysiology of toxicoderma is associated with an adverse drug reaction. The article provides data from Russian and international literature on the role of antiepileptic drugs in these diseases occurrence. It also presents clinical cases of toxic epidermal necrolysis in children caused by anticonvulsants intake.

The risk of Stevens-Johnson syndrome and toxic epidermal necrolysis in new users of antiepileptic drugs

Epilepsia ◽  
2017 ◽  
Vol 58 (12) ◽  
pp. 2178-2185 ◽  
Author(s):  
Noel Frey ◽  
Michael Bodmer ◽  
Andreas Bircher ◽  
Stephan Rüegg ◽  
Susan S. Jick ◽  
...  
Keyword(s):  
Toxic Epidermal Necrolysis ◽  
Antiepileptic Drugs ◽  
Stevens Johnson Syndrome ◽  
Johnson Syndrome
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