scholarly journals The G119S ace ‐1 mutation confers adaptive organophosphate resistance in a nontarget amphipod

2020 ◽  
Vol 13 (4) ◽  
pp. 620-635 ◽  
Author(s):  
Kaley M. Major ◽  
Donald P. Weston ◽  
Michael J. Lydy ◽  
Kara E. Huff Hartz ◽  
Gary A. Wellborn ◽  
...  

Science ◽  
1960 ◽  
Vol 132 (3422) ◽  
pp. 298-299 ◽  
Author(s):  
F. J. Oppenoorth ◽  
K. van Asperen


2007 ◽  
Vol 21 (13) ◽  
pp. 3584-3591 ◽  
Author(s):  
Feng Cui ◽  
Hong Qu ◽  
Jian Cong ◽  
Xiao‐Li Liu ◽  
Chuan‐Ling Qiao


Author(s):  
Blair D. Siegfried ◽  
Michael E. Scharf




2002 ◽  
Vol 92 (3) ◽  
pp. 203-212 ◽  
Author(s):  
D.B. Fragoso ◽  
R.N.C. Guedes ◽  
M.C. Picanço ◽  
L. Zambolim

AbstractIncreasing rates of insecticide use against the coffee leaf miner Leucoptera coffeella (Guérin-Méneville) and field reports on insecticide resistance led to an investigation of the possible occurrence of resistance of this species to some of the oldest insecticides used against it in Brazil: chlorpyrifos, disulfoton, ethion and methyl parathion. Insect populations were collected from ten sites in the state of Minas Gerais, Brazil and these populations were subjected to discriminating concentrations established from insecticide LC99s estimated for a susceptible standard population. Eight of the field-collected populations showed resistance to disulfoton, five showed resistance to ethion, four showed resistance to methyl parathion, and one showed resistance to chlorpyrifos. The frequency of resistant individuals in each population ranged from 10 to 93% for disulfoton, 53 to 75% for ethion, 23 to 76% for methyl parathion, and the frequency of resistant individuals in the chlorpyrifos resistant population was 35%. A higher frequency of individuals resistant to chlorpyrifos, disulfoton and ethion was associated with greater use of insecticides, especially other organophosphates. This finding suggests that cross-selection, mainly between organophosphates, played a major role in the evolution of insecticide resistance in Brazilian populations of L. coffeella. Results from insecticide bioassays with synergists (diethyl maleate, piperonyl butoxide and triphenyl phosphate) suggested that cytochrome P450-dependent monooxygenases may play a major role in resistance with minor involvement of esterases and glutathione S-transferases.



1984 ◽  
Vol 74 (4) ◽  
pp. 677-687 ◽  
Author(s):  
R. J. Wood ◽  
N. Pasteur ◽  
G. Sinégre

AbstractThree French strains of Culex pipiens L. were compared at the fourth larval instar for tolerance to organophosphate and carbamate insecticides, with and without the addition of synergists (the oxidase inhibitors piperonyl butoxide and CGA 84708) (a propynyl compound) and the carboxylesterase inhibitors triphenyl phosphate (TPP) and S,S,S-tributyl phosphorotrithioate (TBPT). The S54 strain was resistant to all the organophosphates tested (chlorpyrifos, malathion, monocrotophos and profenofos) compared to the susceptible LA VIS strain but only slightly tolerant to the two carbamates (carbaryl and naphthyl phenylcarbamate). The MAURIN strain was resistant to all the insecticides, including the carbamates, at a higher level. The action of chlorpyrifos and malathion on S54 was very strongly synergised by TBPT, less strongly by TPP and not at all by piperonyl butoxide. In fact, resistance was enhanced by piperonyl butoxide, as was resistance to monocrotophos and profenofos by CGA 84708. No synergist had much effect on the MAURIN strain, although TPP slightly increased the toxicity of malathion, and piperonyl butoxide and CGA 84708 slightly increased the toxicity of carbaryl. The toxic effect of carbaryl was also increased by the addition of extra acetone. Electrophoretic studies showed that the carboxylesterase enzyme coded by gene Est-20.64 (which is in linkage disequilibrium withEst-3A and acts as a marker for it) was absent from LA VIS but present in the resistant strains; but, whereas S54 was monomorphic for the gene, MAURIN was polymorphic (frequency 0·5). It is concluded that organophosphate resistance in S54 was due to detoxification by carboxylesterase wherease organophosphate and carbamate resistance in MAURIN had a strong non-metabolic component, possibly an insensitive acetylcholinesterase.



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