Clinical insights: Equine herpesvirus myeloencephalopathy: The conundrum of vaccination in performance and leisure horses

2021 ◽  
Vol 53 (6) ◽  
pp. 1088-1090
Author(s):  
Julia H. Kydd
Keyword(s):  
Equine Herpesvirus

The highly O-glycosylated glycoprotein gp2 of equine herpesvirus 1 is encoded by gene 71.

1996 ◽  
Vol 70 (11) ◽  
pp. 8195-8198 ◽  
Author(s):  
J E Wellington ◽  
G P Allen ◽  
A A Gooley ◽  
D N Love ◽  
N H Packer ◽  
...  
Keyword(s):  
Equine Herpesvirus ◽  
Equine Herpesvirus 1 ◽  
Herpesvirus 1

scholarly journals Evaluation of the Variability of the ORF34, ORF68, and MLST Genes in EHV-1 from South Korea

Pathogens ◽  
2021 ◽  
Vol 10 (4) ◽  
pp. 425
Author(s):  
Hyung-Woo Kang ◽  
Eun-Yong Lee ◽  
Kyoung-Ki Lee ◽  
Mi-Kyeong Ko ◽  
Ji-Young Park ◽  
...  
Keyword(s):  
Nucleotide Sequence ◽  
South Korea ◽  
Molecular Level ◽  
Economic Losses ◽  
Equine Herpesvirus ◽  
Equine Herpesvirus 1 ◽  
Mlst Analysis ◽  
Herpesvirus 1 ◽  
First Time ◽  
Group 1

Equine herpesvirus-1 (EHV-1) is an important pathogen in horses. It affects horses worldwide and causes substantial economic losses. In this study, for the first time, we characterized EHV-1 isolates from South Korea at the molecular level. We then aimed to determine the genetic divergences of these isolates by comparing them to sequences in databases. In total, 338 horse samples were collected, and 12 EHV-1 were isolated. We performed ORF30, ORF33, ORF68, and ORF34 genetic analysis and carried out multi-locus sequence typing (MLST) of 12 isolated EHV-1. All isolated viruses were confirmed as non-neuropathogenic type, showing N752 of ORF30 and highly conserved ORF33 (99.7–100%). Isolates were unclassified using ORF68 analysis because of a 118 bp deletion in nucleotide sequence 701–818. Seven EHV-1 isolates (16Q4, 19R166-1, 19R166-6, 19/10/15-2, 19/10/15-4, 19/10/18-2, 19/10/22-1) belonged to group 1, clade 10, based on ORF34 and MLST analysis. The remaining 5 EHV-1 isolates (15Q25-1, 15D59, 16Q5, 16Q40, 18D99) belonged to group 7, clade 6, based on ORF34 and MLST analysis.

scholarly journals Evaluation of a vectored equine herpesvirus type 1 (EHV-1) vaccine expressing H3 haemagglutinin in the protection of dogs against canine influenza

Vaccine ◽  
2008 ◽  
Vol 26 (19) ◽  
pp. 2335-2343 ◽  
Author(s):  
Cristina Rosas ◽  
Gerlinde R. Van de Walle ◽  
Stephan M. Metzger ◽  
Karin Hoelzer ◽  
Edward J. Dubovi ◽  
...  
Keyword(s):  
Equine Herpesvirus ◽  
Herpesvirus Type ◽  
Equine Herpesvirus Type ◽  
Equine Herpesvirus Type 1 ◽  
Canine Influenza

scholarly journals Evaluation of the vaccine potential of an equine herpesvirus type 1 vector expressing bovine viral diarrhea virus structural proteins

2007 ◽  
Vol 88 (3) ◽  
pp. 748-757 ◽  
Author(s):  
Cristina T. Rosas ◽  
Patricia König ◽  
Martin Beer ◽  
Edward J. Dubovi ◽  
B. Karsten Tischer ◽  
...  
Keyword(s):  
Bovine Viral Diarrhea Virus ◽  
Structural Proteins ◽  
Bovine Viral Diarrhea ◽  
Equine Herpesvirus ◽  
Herpesvirus Type ◽  
Diarrhea Virus ◽  
Viral Diarrhea ◽  
Equine Herpesvirus Type 1 ◽  
Viral Diarrhea Virus

Bovine viral diarrhea virus (BVDV) is an economically important pathogen of cattle that is maintained in the population by persistently infected animals. Virus infection may result in reproductive failure, respiratory disease and diarrhoea in naïve, susceptible bovines. Here, the construction and characterization of a novel vectored vaccine, which is based on the incorporation of genes encoding BVDV structural proteins (C, Erns, E1, E2) into a bacterial artificial chromosome of the equine herpesvirus type 1 (EHV-1) vaccine strain RacH, are reported. The reconstituted vectored virus, rH_BVDV, expressed BVDV structural proteins efficiently and was indistinguishable from parental vector virus with respect to growth properties in cultured cells. Intramuscular immunization of seronegative cattle with rH_BVDV resulted in induction of BVDV-specific serum neutralizing and ELISA antibodies. Upon experimental challenge infection of immunized calves with the heterologous BVDV strain Ib SE5508, a strong anamnestic boost of the neutralizing-antibody response was observed in all vaccinated animals. Immunized animals presented with reduced viraemia levels and decreased nasal virus shedding, and maintained higher leukocyte counts than mock-vaccinated controls.

Infection with Equine Herpesvirus 1 (EHV-1) Strain HVS25A in Pregnant Mice

1999 ◽  
Vol 120 (1) ◽  
pp. 15-27 ◽  
Author(s):  
C. Walker ◽  
V.M. Perotti ◽  
D.N. Love ◽  
J.M. Whalley
Keyword(s):  
Equine Herpesvirus ◽  
Equine Herpesvirus 1 ◽  
Pregnant Mice ◽  
Herpesvirus 1
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