THE EFFECT OF COLLECTIVE DISPERSAL ON THE GENETIC STRUCTURE OF A SUBDIVIDED POPULATION

Evolution ◽  
2013 ◽  
Vol 67 (6) ◽  
pp. 1649-1659 ◽  
Author(s):  
Jonathan M. Yearsley ◽  
Frédérique Viard ◽  
Thomas Broquet
Keyword(s):  
Genetic Structure ◽  
Subdivided Population

scholarly journals GENETIC STRUCTURE OF PILEOLARIA PSEUDOMILITARIS (POLYCHAETA: SPIRORBIDAE)

Genetics ◽  
1980 ◽  
Vol 96 (3) ◽  
pp. 711-726
Author(s):  
Richard Beckwitt
Keyword(s):  
Genetic Structure ◽  
Founder Effect ◽  
Gene Diversity ◽  
Phosphoglucose Isomerase ◽  
Diversity Analysis ◽  
Habitat Types ◽  
Gene Frequencies ◽  
Selection Pressures ◽  
Subdivided Population

ABSTRACT The genetic structure of Pileolaria pseudomilitaris was studied by means of gene-diversity analysis of allozyme frequencies. At an esterase locus, most of the gene diversity was due to subdivision of the population into colonies and subpopulations separated by less than 100 meters. Gene frequencies at a phosphoglucose isomerase locus were similar over many kilometers, but differed between two habitat types. Differences between colonies are attributed to drift and founder effect; similarities over greater distances are attributed to similar selection pressures. A mathematical appendix details the method of gene diversity analysis for a multi-leveled, hierarchically subdivided population.

Differential Pathways to PTSD: The Phenotypic and Genetic Structure of Psychiatric Comorbidity

2009 ◽  
Author(s):  
Erika Wolf ◽  
Mark Miller ◽  
Karestan Koenen
Keyword(s):  
Genetic Structure ◽  
Psychiatric Comorbidity

Genetic structure of IDDM1: two separate regions in the major histocompatibility complex contribute to susceptibility or protection. Belgian Diabetes Registry

Diabetes ◽  
1998 ◽  
Vol 47 (2) ◽  
pp. 263-269 ◽  
Author(s):  
P. Hanifi Moghaddam ◽  
P. de Knijf ◽  
B. O. Roep ◽  
B. Van der Auwera ◽  
A. Naipal ◽  
...  
Keyword(s):  
Major Histocompatibility Complex ◽  
Genetic Structure ◽  
Major Histocompatibility ◽  
Diabetes Registry ◽  
Histocompatibility Complex

Modeling of dynamic mosaicism on ring chromosomes in human fibroblasts and IPSCS

2020 ◽  
pp. 12-13
Author(s):  
Т.В. Никитина ◽  
А.А. Кашеварова ◽  
М.М. Гридина ◽  
А.А. Хабарова ◽  
А.Г. Мензоров ◽  
...  
Keyword(s):  
Genetic Structure ◽  
Human Fibroblasts ◽  
Cellular Heterogeneity ◽  
Mitotic Stability ◽  
Factors Affecting ◽  
Ring Chromosomes ◽  
Cell Clones ◽  
Mitotic Instability ◽  
Mitotic Behavior

Митотическая нестабильность кольцевых хромосом может приводить к появлению клеточных клонов с различной генетической структурой. В качестве модели нестабильности кольцевых хромосом в митозе мы использовали фибробласты от пациентов с r(8), r(13), r(18) и r(22) и полученные из них индуцированные плюрипотентные стволовые клетки (ИПСК). Линии ИПСК с r(22) имели относительно стабильный кариотип на протяжении десятков (до 60) пассажей и сохраняли неизменную структуру кольцевой хромосомы. Кариотип линий ИПСК с r(8) и r(18) на ранних пассажах стабильный, планируется его изучение на поздних пассажах. Наибольшее разнообразие кариотипа выявлено в линиях ИПСК с r(13), в которых наблюдали различные перестройки и выраженную клеточную гетерогенность. Определение факторов, влияющих на митотическую стабильность кольцевых хромосом, может иметь значение для консультирования пациентов. Mitotic instability of ring chromosomes can lead to the appearance of cell clones with different genetic structure. IPSCs from fibroblasts of patients with r(8), r(13), r(18), and r(22) were used as a model of ring chromosomes mitotic behavior. Karyotypes of iPSC lines with r(8) and r(18) have so far been evaluated only in the early passages, lines with r(22) have maintained a relatively stable karyotype up to 60 passages. The occurrence of rearrangements and cellular heterogeneity was found characteristic for r(13) iPSCs. The determination of factors affecting the ring chromosomes mitotic stability would be beneficial for the patient’s prognosis.

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