scholarly journals A humanized version of Foxp2 affects ultrasonic vocalization in adult female and male mice

2021 ◽  
Author(s):  
Sophie Merten ◽  
Christine Pfeifle ◽  
Sven Künzel ◽  
Svenja Hoier ◽  
Diethard Tautz
Keyword(s):  
Adult Female ◽  
Ultrasonic Vocalization ◽  
Male Mice

scholarly journals Intrauterine growth restriction affects diaphragm function in adult female and male mice

2019 ◽  
Vol 55 (1) ◽  
pp. 229-235 ◽  
Author(s):  
Maddison R. Francis ◽  
Gavin J. Pinniger ◽  
Peter B. Noble ◽  
Kimberley C. W. Wang
Keyword(s):  
Adult Female ◽  
Intrauterine Growth Restriction ◽  
Growth Restriction ◽  
Male Mice ◽  
Intrauterine Growth ◽  
Diaphragm Function

scholarly journals Social isolation produces no effect on ultrasonic vocalization production in adult female CBA/CaJ mice

PLoS ONE ◽  
2019 ◽  
Vol 14 (3) ◽  
pp. e0213068 ◽  
Author(s):  
Laurel A. Screven ◽  
Micheal L. Dent
Keyword(s):  
Social Isolation ◽  
Adult Female ◽  
Ultrasonic Vocalization

scholarly journals The Gubernaculum in adult female, adult male and TFM male mice

1993 ◽  
Vol 16 (6) ◽  
pp. 380-384 ◽  
Author(s):  
A. L. GRIFFITHS ◽  
Y. MOMOSE ◽  
J. M. HUTSON
Keyword(s):  
Adult Female ◽  
Adult Male ◽  
Male Mice ◽  
Female Adult

Effect of aging on the recovery following contraction-induced injury in muscles of female mice

2006 ◽  
Vol 101 (3) ◽  
pp. 887-892 ◽  
Author(s):  
Erik P. Rader ◽  
John A. Faulkner
Keyword(s):  
Adult Female ◽  
Skeletal Muscles ◽  
Isometric Force ◽  
Recovery Phase ◽  
Maximum Force ◽  
Male Mice ◽  
Flexor Muscle ◽  
Female Mice ◽  
Age Related ◽  
Maximum Isometric Force

By the age of 80 yr, the skeletal muscles of men and women decrease in mass and maximum force by ∼30%. Severe contraction-induced injury may contribute to these age-related declines. One to two months after a 225 lengthening contraction protocol (LCP), muscles of young/adult male mice recovered completely, whereas those of old male mice sustained deficits of ∼15% in mass and ∼25% in maximum force. Although gender-related differences in the early events of contraction-induced injury have been reported, the recovery phase of muscles in old female animals has not been investigated. The hypothesis tested was that 2 mo after a severe LCP to the plantar flexor muscle group, the magnitude of recovery of mass and force for old female mice is less than that for adult female mice. The LCP was administered to muscles of adult and old, female C57BL/6 mice. At 3 days, 1 mo, and 2 mo following the LCP, maximum isometric force was measured, and muscles were removed and weighed. Two months following the LCP, the muscles of adult female mice recovered mass and force. In contrast, for old female mice, even after 2 mo, muscle masses were decreased by 11% and maximum forces by 38%. We conclude that, as reported previously for old male mice, a severe contraction-induced injury to muscles of old female mice results in prolonged deficits in mass and force.

Localization and sex-difference of steroid receptor coactivator-1 immunoreactivities in the brain of adult female and male mice

Steroids ◽  
2011 ◽  
Vol 76 (3) ◽  
pp. 269-279 ◽  
Author(s):  
Chen Bian ◽  
Dongmei Zhang ◽  
Qiang Guo ◽  
Wenqin Cai ◽  
Jiqiang Zhang
Keyword(s):  
Sex Difference ◽  
Adult Female ◽  
Steroid Receptor ◽  
Male Mice ◽  
Steroid Receptor Coactivator ◽  
The Brain

scholarly journals Female- and Intruder-induced Ultrasonic Vocalizations in C57BL/6J Mice as Proxy Indicators for Animal Wellbeing

2019 ◽  
Vol 69 (5) ◽  
pp. 374-383
Author(s):  
Brian J Smith ◽  
Kate E P Bruner ◽  
Lon V Kendall
Keyword(s):  
Adult Female ◽  
Acute Inflammation ◽  
Clinical Signs ◽  
Ultrasonic Vocalizations ◽  
Sublethal Dose ◽  
Male Mice ◽  
Female Mice ◽  
Female Urine ◽  
Proxy Indicators ◽  
Affiliative Behaviors

Female urine-induced male mice ultrasonic vocalizations (FiUSV) are ultrasonic vocalizations produced by adult male mice after presentation of adult female urine, whereas intruder-induced ultrasonic vocalizations (IiUSV) are produced by resident adult female mice when interacting with an intruder female mouse. These affiliative behaviors may be reduced when mice have decreased wellbeing or are in pain and distress. To determine whether FiUSV and IiUSV can be used as proxy indicators of animal wellbeing, we assessed FiUSV produced by male C57BL/6J mice in response to female urine and IiUSV produced by female C57BL/6J mice in response to a female intruder at baseline and 1 and 3 h after administration of a sublethal dose of LPS (6 or 12.5 mg/kg IP) or an equal volume of saline. Behavior was assessed by evaluating orbital tightness, posture, and piloerection immediately after USV collection. We hypothesized that LPS-injected mice would have a decreased inclination to mate or to interact with same-sex conspecifics and therefore would produce fewer USV. At baseline, 32 of 33 male mice produced FiUSV (149 ± 127 USV in 2 min), whereas all 36 female mice produced IiUSV (370 ± 156 USV in 2 min). Saline-injected mice showed no change from baseline at the 1- and 3-h time points, whereas LPS-injected mice demonstrated significantly fewer USV than baseline, producing no USV at both 1 and 3 h. According to orbital tightness, posture, and piloerection, LPS-injected mice showed signs of poor wellbeing at 3 h but not 1 h. These findings indicate that FiUSV and IiUSV can be used as proxy indicators of animal wellbeing associated with acute inflammation in mice and can be detected before the onset of clinical signs.

Effects of testosterone onHeterakis spumosainfections in mice

Parasitology ◽  
1992 ◽  
Vol 105 (2) ◽  
pp. 335-342 ◽  
Author(s):  
A. Harder ◽  
F. Wunderlich ◽  
P. Marinovski
Keyword(s):  
Small Intestine ◽  
Life Cycle ◽  
Young Adult ◽  
Adult Female ◽  
Post Infection ◽  
Male Mice ◽  
Patent Period ◽  
Intestinal Nematode ◽  
Early Phases

SUMMARYThis study describes the effects of testosterone (Te) on the intestinal nematodeHeterakis spumosain mice. The course ofHeterakisinfections is apparently under Te-control. At high circulating Te-levels as occurring in intact males, Te-treated females, and Te-treated castrated males, the period of release ofHeterakiseggs in mouse faeces is greatly extended and the number of eggs released per unit time is markedly elevated in comparison to low Te-levels, as found in untreated females and castrated male mice. Also, the onset of the patent period occurs earlier in Te-treated mice. Testosterone also accelerates development and growth of both female and male worms ofHeterakisin mice. Thus, young adult male worms can be observed in the upper colon of Te-treated castrated male mice on day 21 post-infection (p. i.), whereas, at that time, only L4larvae are present in Te-untreated male castrates. Testosterone also favours the survival of nematodes in hosts. In untreated male castrates, the number of worms present on day 7 p.i. (L2larvae) is approximately two thirds higher than that found on day 21 p.i. However, such a reduction in the number of worms does not occur in Te-treated castrated mice during the same period of time. The early phases of the life-cycle ofHeterakis, i.e. hatching in the small intestine and final settling of L2larvae in the upper colon are independent of Te. Also, Te does not affect motility and even slightly reduces the fecundity of adult female wormsin vitro. Our data suggest that Te and/or Te-metabolites and/or Te-induced host factor(s) accelerate the development and growth ofH. spumosaand favour the survival ofHeterakisin the colon of mice.

Intrauterine contiguity influences regulatory activity in adult female and male mice

1986 ◽  
Vol 20 (1) ◽  
pp. 7-12 ◽  
Author(s):  
C KINSLEY
Keyword(s):  
Adult Female ◽  
Male Mice ◽  
Regulatory Activity

Juvenile male mice: An attempt to accelerate testis function by exposure to adult female stimuli

1978 ◽  
Vol 21 (6) ◽  
pp. 1009-1013 ◽  
Author(s):  
Bruce Svare ◽  
Andrzej Bartke ◽  
Foteos Macrides
Keyword(s):  
Adult Female ◽  
Juvenile Male ◽  
Male Mice

Radiation-induced Gene Mutation in Adult Female and Foetal Male Mice

1958 ◽  
Vol 31 (368) ◽  
pp. 407-411 ◽  
Author(s):  
T. C. Carter
Keyword(s):  
Gene Mutation ◽  
Adult Female ◽  
Male Mice ◽  
Radiation Induced
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