Supraspinatus Muscle Architecture and Physiology in a Rabbit Model of Tenotomy and Repair

Chronic rotator cuff tears can cause severe functional deficits. Addressing the chronic fatty and fibrotic muscle changes is of high clinical interest; however, the architectural and physiological consequences of chronic tear and repair are poorly characterized. We present a detailed architectural and physiological analysis of chronic tear and repair (both over 8 and 16 weeks) compared to age-matched control rabbit supraspinatus (SSP) muscles. Using female New Zealand White Rabbits (N=30, n=6/group) under 2% isofluorane anesthesia, the SSP was surgically isolated and maximum isometric force measured at 4-6 muscle lengths. Architectural analysis was performed, and maximum isometric stress was computed. Whole muscle length-tension curves were generated using architectural measurements to compare experimental physiology to theoretical predictions. Architectural measures are consistent with persistent radial and longitudinal atrophy over time in tenotomy that fail to recover after repair. Maximum isometric force was significantly decreased after 16 wks tenotomy and not significantly improved after repair. Peak isometric force reported here are greater than prior reports of rabbit SSP force after tenotomy. Peak stress was not significantly different between groups and consistent with prior literature of SSP stress. Muscle strain during contraction was significantly decreased after 8-wks of tenotomy and repair, indicating effects of tear and repair on muscle function. The experimental length-tension data was overlaid with predicted curves for each experimental group (generated from structural data), exposing the altered structure-function relationship for tenotomy and repair over time. Data presented here contribute to understanding the physiological implications of disease and repair in the rotator cuff

Evaluation of Training with Elastic Bands on Strength and Fatigue Indicators in Paralympic Powerlifting

Background: Variable resistance training has recently become a component of strength and conditioning programs. Objective: This randomized counterbalanced cross-over study aimed to investigate the use of elastic bands (EB) and the traditional method (TRAD) and force indicators in a training session. Methods: 12 Paralympic athletes (age: 28.60 ± 7.60 years) participated in this three-week study. In the first week, the participants were familiarized with EB and TRAD and were tested for maximal repetition (1-RM). The research occurred in weeks 2 and 3, which included the pre-post training, during which the following measures were extracted: maximum isometric force (MIF), the peak torque (PT), rate of force development (RFD), fatigue index (FI), and time to MIF (Time). The athletes performed two tests, EB and TRAD, separated by a one-week interval. Results: Significant differences were found between the pre- and post-test for 1RM (p = 0.018, η2p = 0.412), MIF (p = 0.011, η2p = 0.415), PT (p = 0.012, η2p = 0.413), and RFD (p = 0.0002, η2p = 0.761). With the use of EB, there was a difference in RFD between TRAD before and EB after (p = 0.016, η2p = 0.761). There were significant differences in the before and after for FI between TRAD and EB (p < 0.001) and for Time (p < 0.001), indicating that training with the use of elastic bands promotes overload, characterized by increased fatigue and decreased strength. Conclusions: Training with EB did not decrease 1RM, PT, MIF or RFD, however, there was an increase in fatigue and time to reach MIF when compared to the method with fixed resistance.

Classifying muscle parameters with artificial neural networks and simulated lateral pinch data

Objective Hill-type muscle models are widely employed in simulations of human movement. Yet, the parameters underlying these models are difficult or impossible to measure in vivo. Prior studies demonstrate that Hill-type muscle parameters are encoded within dynamometric data. But, a generalizable approach for estimating these parameters from dynamometric data has not been realized. We aimed to leverage musculoskeletal models and artificial neural networks to classify one Hill-type muscle parameter (maximum isometric force) from easily measurable dynamometric data (simulated lateral pinch force). We tested two neural networks (feedforward and long short-term memory) to identify if accounting for dynamic behavior improved accuracy. Methods We generated four datasets via forward dynamics, each with increasing complexity from adjustments to more muscles. Simulations were grouped and evaluated to show how varying the maximum isometric force of thumb muscles affects lateral pinch force. Both neural networks classified these groups from lateral pinch force alone. Results Both neural networks achieved accuracies above 80% for datasets which varied only the flexor pollicis longus and/or the abductor pollicis longus. The inclusion of muscles with redundant functions dropped model accuracies to below 30%. While both neural networks were consistently more accurate than random guess, the long short-term memory model was not consistently more accurate than the feedforward model. Conclusion Our investigations demonstrate that artificial neural networks provide an inexpensive, data-driven approach for approximating Hill-type muscle-tendon parameters from easily measurable data. However, muscles of redundant function or of little impact to force production make parameter classification more challenging.

Static and Dynamic Strength Indicators in Paralympic Power-Lifters with and without Spinal Cord Injury

Background: In Paralympic powerlifting (PP), athletes with and without spinal cord injury (SCI) compete in the same category. Athletes with SCI may be at a disadvantage in relation to the production of muscle strength and the execution of motor techniques. Objective: To analyze the indicators force, dynamic and static, at different intensities, on performance in athletes with and without SCI. Methods: The sample was composed of two groups of PP athletes: SCI (30.57 ± 4.20 years) and other deficiencies (OD; 25.67 ± 4.52 years). Athletes performed a test of maximum isometric force (MIF), time to MIF (Time), rate of force development (RFD), impulse, variability and fatigue index (FI), dynamic tests Mean Propulsive Velocity (MPV), Maximum Velocity (Vmax) and Power. Results: There were differences in the SCI in relation to OD, 50% 1RM (p < 0.05), in relation to MPV and Vmax. There were no differences in the static force indicators. Regarding EMG, there were differences between the SCI triceps in relation to the previous deltoid (p = 0.012). Conclusion: We concluded that the static and dynamic strength indicators are similar in Paralympic powerlifting athletes with spinal cord injury and other disabilities.

Evaluation of Strength and Muscle Activation Indicators in Sticking Point Region of National-Level Paralympic Powerlifting Athletes

Background: The sticking region is considered an intervening factor in the performance of the bench press with high loads. Objective: To evaluate the strength indicators in the sticking point region in Powerlifting Paralympic athletes. Methods: Twelve Brazilian Powerlifting Paralympic athletes performed maximum isometric force (MIF), rate of force development (RFD), time at MIF, velocity, dynamic time in sticking, and surface electromyography in several distances from the bar to the chest. Results: For velocity, there was a difference between the pre-sticking and sticking region (1.98 ± 0.32 and 1.30 ± 0.43, p = 0.039) and dynamic time between the pre-sticking and the sticking region (0.40 ± 0.16 and 0.97 ± 0.37, p = 00.021). In static test for the MIF, differences were found between 5.0 cm and 15.0 cm (CI 95% 784; 1088; p = 0.010) and between 10.0 cm and 5.0 cm (CI 95% 527; 768; p < 0.001). Regarding the RFD, differences were found (CI 95% 938; 1240; p = 0.004) between 5.0 cm and 25.0 cm and between 10.0 cm and 25.0 cm (CI 95% 513; 732; p < 0.001). In relation to time, there were differences between 5.0 cm and 15.0 cm (CI 95% 0.330; 0.515; p < 0.001), 5.0 cm, and 25.0 cm (CI 95% 0.928; 1.345; p = 0.001), 10.0 cm and 15.0 cm (p < 0.05) and 15.0 cm and 25.0 cm (p < 0.05). No significant differences were observed between the muscles in electromyography, although the triceps showed the highest muscle activation values. Conclusions: The maximum isometric force, rate of force development, time, velocity, and dynamic time had lower values, especially in the initial and intermediate phases in the sticking region.

MAXIMUM ISOMETRIC MUSCLE STRENGTH AS A PREDICTOR OF ONE REPETITION MAXIMUM IN THE SQUAT TEST

This study aims to determine whether maximum isometric muscle strength, exerted at a certain angle in the knee joint (80 °, 110 °, and 140 °), may be used as a predictor of 1RM in the squat movement task. A group of twenty-four male students (N = 24) took part in the research in 2 separate sessions and 7 days of rest between each. In the first session, the anthropometric measurements and assessment of muscle strength, that is 1RM, were measured by maximum repetition to failure method on the Smith machine. The maximum isometric force (Fmax) of the leg muscles was measured by the Alternating Consecutive Maximum Contraction Test in laboratory conditions on a Smith machine using a dynamometer probe and the Globus Ergo Tesys System 1000 software system. Analyzing the results based on linear regression, the authors conclude that, with an accuracy of 84.5%, we can estimate 1RM in the squat exercise measuring the maximum isometric force exerted at an angle in the knee joint of 140 °. The results obtained by this research can be used in practice when assessing 1 RM based on the measurement of the maximum isometric force for a given movement task.

In vivo supraspinatus muscle contractility and architecture in rabbit

We introduce an improved method to assess rabbit supraspinatus muscle physiology. Maximum isometric force measured for the rabbit supraspinatus was dramatically greater than previous reports in the literature. Consequently, the isometric contractile stress reported is almost 10 times greater than previous reports of rabbit supraspinatus, but similar to available literature of other mammalian skeletal muscle. We show that previous reports of peak supraspinatus isometric force were subphysiological by ∼90%

Maximum isometric tongue force in patients with obstructive sleep apnoea

Background Obstructive sleep apnea (OSA) is a sleep disorder with a prevalence of 9–38%. The underlying pathology in OSA is a collapse of the upper airway. Especially in more severely affected patients, this collapse is often located at the level of the tongue base. Therefore, various implantable systems (anchors and ligament techniques) were developed to prevent or overcome this collapse. These systems are exposed to various forces. Different models have been developed to measure these forces and data comparing forces in healthy individuals with OSA patients are rare. Purpose Purpose of the study was to evaluate possible differences in tongue forces between healthy individuals and patients with OSA. Method To evaluate maximum isometric tongue forces, we conducted a matched pair design study including 20 healthy individuals and 20 patients suffering from OSA. Maximum isometric tongue forces were measured in an anterior/posterior direction with the help of self-designed new device that clamps the tongue. Results We could show that the maximum isometric force does not differ significantly in healthy individuals (10.7 ± 5.2N) from patients with OSA (14.4 ± 6.3N). Conclusion Currently there are no indications that maximum isometric tongue force does differ in healthy individuals and patients with OSA. Higher, as well as lower, tongue forces in patients with OSA seem not to differ from healthy subjects and therefore may not be needed to consider, in the development of tongue management devices, for OSA patients.

Can Creatine Supplementation Interfere with Muscle Strength and Fatigue in Brazilian National Level Paralympic Powerlifting?

The aim of the present study was to analyze the effect of creatine (Cr) supplementation on peak torque (PT) and fatigue rate in Paralympic weightlifting athletes. Eight Paralympic powerlifting athletes participated in the study, with 25.40 ± 3.30 years and 70.30 ± 12.15 kg. The measurements of muscle strength, fatigue index (FI), peak torque (PT), force (kgf), force (N), rate of force development (RFD), and time to maximum isometric force (time) were determined by a Musclelab load cell. The study was performed in a single-blind manner, with subjects conducting the experiments first with placebo supplementation and then, following a 7-day washout period, beginning the same protocol with creatine supplementation for 7 days. This sequence was chosen because of the lengthy washout of creatine. Regarding the comparison between conditions, Cr supplementation did not show effects on the variables of muscle force, peak torque, RFD, and time to maximum isometric force (p > 0.05). However, when comparing the results of the moments with the use of Cr and placebo, a difference was observed for the FI after seven days (U3: 1.12; 95% CI: (0.03, 2.27); p = 0.02); therefore, the FI was higher for placebo. Creatine supplementation has a positive effect on the performance of Paralympic powerlifting athletes, reducing fatigue index, and keeping the force levels as well as PT.