Bleeding with iron deposition and vascular remodelling in subchondral cysts: A newly discovered feature unique to haemophilic arthropathy

Haemophilia ◽  
2021 ◽  
Author(s):  
Jenny Y. Zhou ◽  
Jonathan H. Wong ◽  
Zachary T. Berman ◽  
Alecio F. Lombardi ◽  
Eric Y. Chang ◽  
...  
Keyword(s):  
Iron Deposition ◽  
Vascular Remodelling ◽  
Haemophilic Arthropathy

Circulating fibrocytes in pulmonary vascular remodelling

Pneumologie ◽  
2009 ◽  
Vol 63 (02) ◽  
Author(s):  
V Nikam ◽  
G Hild ◽  
R Schermuley ◽  
R Dumitrascu ◽  
N Weissmann ◽  
...  
Keyword(s):  
Vascular Remodelling ◽  
Pulmonary Vascular Remodelling ◽  
Circulating Fibrocytes

Iron status in diabetes mellitus

2019 ◽  
pp. 7-12
Keyword(s):  
Diabetes Mellitus ◽  
Beta Cells ◽  
Defense Mechanism ◽  
Acute Stress ◽  
Islet Cells ◽  
Iron Status ◽  
Acute Phase Reactant ◽  
Iron Deposition ◽  
Muscle Tissues ◽  
High Production

Diabetes mellitus can be defined as chronic metabolic disease which results from either relative or complete absence of insulin by the pancreatic beta islet cells. This in-turn may lead to hyperglycemia due to disturbances in the metabolism of glucose. In the human body, iron is con- sidered to be an effective pro-oxidant and participates in the generation of reactive oxygen species (ROS) such as hydroxyl radical. Because of the poor antioxidant defense mechanism of beta cells (low production of antioxidant enzymes such as catalase, glutathione peroxidase and dismutase), so they are highly prone to iron-induced oxidative stress and iron deposition in it and this will lead to apoptosis, and subsequently insulin deficiency. This iron deposition in beta cells will also lead to insulin resistance by reducing insulin extracting ability of the liver and inhibiting glucose uptake in muscle tissues and fats, this in turn will result in high production of hepatic glucose. Ferritin which is an acute phase reactant protein, that responds to acute stress like trauma, infections, tissue necrosis and surgery, it can produce diabetes mellitus either through inflammation or by increasing iron stores.

Noninvasive Assessment of Fat and Iron Deposition in the Liver by PDFF and T2* Measurement Using the 6-Point DIXON Method

2019 ◽  
Author(s):  
Yasue Takeuchi ◽  
Satoshi Saitoh ◽  
Shunichiro Fujiyama ◽  
Yusuke Kawamura ◽  
Hitomi Sezaki ◽  
...  
Keyword(s):  
Iron Deposition ◽  
Dixon Method ◽  
Noninvasive Assessment

Vascular Remodelling in Well-controlled Hypertensive Patients: The Challenge of Residual Risk Management

2017 ◽  
Vol 23 (10) ◽  
pp. 1445-1452 ◽  
Author(s):  
Massimo Puato ◽  
Chiara Nardin ◽  
Marta Zanon ◽  
Paolo Palatini ◽  
Paolo Pauletto ◽  
...  
Keyword(s):  
Risk Management ◽  
Residual Risk ◽  
Vascular Remodelling ◽  
Hypertensive Patients
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