Impact of abuse on migraine‐related sensory hypersensitivity symptoms: Results from the American Registry for Migraine Research

2021 ◽  
Author(s):  
Meesha Trivedi ◽  
Gina Dumkrieger ◽  
Catherine D. Chong ◽  
David W. Dodick ◽  
Todd J. Schwedt
Keyword(s):  
Sensory Hypersensitivity

Sensory hypersensitivity occurs soon after whiplash injury and is associated with poor recovery

Pain ◽  
2003 ◽  
Vol 104 (3) ◽  
pp. 509-517 ◽  
Author(s):  
Michele Sterling ◽  
Gwendolen Jull ◽  
Bill Vicenzino ◽  
Justin Kenardy
Keyword(s):  
Whiplash Injury ◽  
Sensory Hypersensitivity ◽  
Poor Recovery

scholarly journals The Opiorphin Analog STR-324 Decreases Sensory Hypersensitivity in a Rat Model of Neuropathic Pain

2018 ◽  
Vol 126 (6) ◽  
pp. 2102-2111
Author(s):  
Alain Van Elstraete ◽  
Philippe Sitbon ◽  
Leila Hamdi ◽  
Victor Juarez-Perez ◽  
Jean-Xavier Mazoit ◽  
...  
Keyword(s):  
Neuropathic Pain ◽  
Rat Model ◽  
Sensory Hypersensitivity

Localized experimental bone metastasis drives osteolysis and sensory hypersensitivity at distant non-tumor-bearing sites

2015 ◽  
Vol 153 (1) ◽  
pp. 9-20 ◽  
Author(s):  
Dareen M. Abdelaziz ◽  
Laura S. Stone ◽  
Svetlana V. Komarova
Keyword(s):  
Bone Metastasis ◽  
Sensory Hypersensitivity ◽  
Tumor Bearing

scholarly journals Contribution of CD137L to Sensory Hypersensitivity in a Murine Model of Neuropathic Pain

eNeuro ◽  
2018 ◽  
Vol 5 (5) ◽  
pp. ENEURO.0218-18.2018 ◽  
Author(s):  
Alexa A. Wakley ◽  
Reno Leeming ◽  
Jenn Malon ◽  
Taxiarhia J. Arabatzis ◽  
Woon Yuen Koh ◽  
...  
Keyword(s):  
Neuropathic Pain ◽  
Murine Model ◽  
Sensory Hypersensitivity

Brief Report: The Impact of Sensory Hypersensitivity and Intolerance of Uncertainty on Anxiety in Williams Syndrome

2018 ◽  
Vol 48 (11) ◽  
pp. 3958-3964 ◽  
Author(s):  
Mirko Uljarević ◽  
Izelle Labuschagne ◽  
Rebecca Bobin ◽  
Anna Atkinson ◽  
Darren R. Hocking
Keyword(s):  
Williams Syndrome ◽  
Intolerance Of Uncertainty ◽  
Sensory Hypersensitivity ◽  
The Impact

Sensory Hypersensitivity Symptoms in Migraine With vs Without Aura: Results From the American Registry for Migraine Research

2020 ◽  
Vol 60 (3) ◽  
pp. 506-514
Author(s):  
Talia A. Pearl ◽  
Gina Dumkrieger ◽  
Catherine D. Chong ◽  
David W. Dodick ◽  
Todd J. Schwedt
Keyword(s):  
Sensory Hypersensitivity

scholarly journals Self-perceived attention difficulties are associated with sensory hypersensitivity in migraine

2020 ◽  
Vol 176 (10) ◽  
pp. 829-838 ◽  
Author(s):  
Y. Lévêque ◽  
R. Masson ◽  
L. Fornoni ◽  
A. Moulin ◽  
A. Bidet-Caulet ◽  
...  
Keyword(s):  
Sensory Hypersensitivity ◽  
Attention Difficulties

scholarly journals Regular Exercise Reverses Sensory Hypersensitivity in a Rat Neuropathic Pain Model

2011 ◽  
Vol 114 (4) ◽  
pp. 940-948 ◽  
Author(s):  
Nicola J. Stagg ◽  
Heriberto P. Mata ◽  
Mohab M. Ibrahim ◽  
Erik J. Henriksen ◽  
Frank Porreca ◽  
...  
Keyword(s):  
Chronic Pain ◽  
Neuropathic Pain ◽  
Exercise Training ◽  
Aerobic Exercise ◽  
Opioid Receptor ◽  
Endogenous Opioids ◽  
Receptor Antagonists ◽  
Endogenous Opioid ◽  
Sensory Hypersensitivity ◽  
Opioid Receptor Antagonists

Background Exercise is often prescribed as a therapy for chronic pain. Short-term exercise briefly increases the production of endogenous analgesics, leading to transient antinociception. In limited studies, exercise produced sustained increases in endogenous opioids, sustained analgesia, or diminished measures of chronic pain. This study tests the hypothesis that regular aerobic exercise leads to sustained reversal of neuropathic pain by activating endogenous opioid-mediated pain modulatory systems. Methods After baseline measurements, the L5 and L6 spinal nerves of male Sprague-Dawley rats were tightly ligated. Animals were randomized to sedentary or 5-week treadmill exercise-trained groups. Thermal and tactile sensitivities were assessed 23 h after exercise, using paw withdrawal thresholds to von Frey filaments and withdrawal latencies to noxious heat. Opioid receptor antagonists were administered by subcutaneous, intrathecal, or intracerebroventricular injection. Opioid peptides were quantified using immunohistochemistry with densitometry. Results Exercise training ameliorated thermal and tactile hypersensitivity in spinal nerve-ligated animals within 3 weeks. Sensory hypersensitivity returned 5 days after discontinuation of exercise training. The effects of exercise were reversed by using systemically or intracerebroventricularly administered opioid receptor antagonists and prevented by continuous infusion of naltrexone. Exercise increased β-endorphin and met-enkephalin content in the rostral ventromedial medulla and the mid-brain periaqueductal gray area. Conclusions Regular moderate aerobic exercise reversed signs of neuropathic pain and increased endogenous opioid content in brainstem regions important in pain modulation. Exercise effects were reversed by opioid receptor antagonists. These results suggest that exercise-induced reversal of neuropathic pain results from an up-regulation of endogenous opioids.

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