Be aware of collider bias – comment on the association of carotid artery calcification with oral infections and mortality amongst symptomatic cardiovascular disease patients

2021 ◽  
Vol 54 (4) ◽  
pp. 639-640
Author(s):  
E. Raittio
Author(s):  
Inas A. Ali ◽  
Shatha H. Ali

The present study aimed to assess the potential impact of serum concentration of undercarboxylated osteocalcin (the active form of osteocalcin) and fibroblast growth factor-23 on the incidence of cardiovascular diseases in type 2 diabetics with carotid artery calcification and the possible association with metabolic changes in relation to glucose and minerals homeostasis. This study included 52 men with carotid artery calcification type 2 diabetes mellitus. These patients were categorized; as follows: group A includes 30 patients who had cardiovascular disease and group B includes 22 patients who had no cardiovascular disease. These groups were compared with 25 apparently healthy control (Group C).  It has been shown that fasting serum glucose, HbA1c, homeostatic model assessment of insulin resistance and undercarboxylated osteocalcin values were significantly different in group A and B as compared with control. Also, undercarboxylated osteocalcin was negatively correlated with fasting serum glucose and HbA1c in group A and B. Furthermore, mean serum fibroblast growth factor level was significantly different among the three studied groups, with highest levels in group A. In type 2 diabetic patients with normal kidney function and carotid artery calcification, fibroblast growth factor-23 is associated with cardiovascular disease while undercarboxylated osteocalcin does not. 


2020 ◽  
Vol 54 (1) ◽  
pp. 15-25 ◽  
Author(s):  
S. Paju ◽  
M. Pietiäinen ◽  
J. M. Liljestrand ◽  
L. Lahdentausta ◽  
A. Salminen ◽  
...  

2021 ◽  
Vol 54 (4) ◽  
pp. 638-638
Author(s):  
S. Paju ◽  
M. Pietiäinen ◽  
J. M. Liljestrand ◽  
L. Lahdentausta ◽  
A. Salminen ◽  
...  

2007 ◽  
Vol 01 (03) ◽  
pp. 132-138 ◽  
Author(s):  
Yildiray Sisman ◽  
Elif Tarim Ertas ◽  
Cumali Gokce ◽  
Ahmed Menku ◽  
Mustafa Ulker ◽  
...  

ABSTRACTObjectives: The aim of this study is to determine retrospectively the presence of carotid artery calcifications (CACs) detected on panoramic radiographs (PRs) in a group of Turkish population. Further, the relationships between CACs and gender, life style, and medical history were evaluated.Methods:During the years 2004 to 2006, a random sample of 1282 PRs was collected from patients older than 40 years who were being treated by the School of Dentistry, Erciyes University. Of these 1282 PRs, 750 PRs were included in this study. Medical data was collected from the archival records of the dental school.Results: About 38 (5.06%) CACs were found on the PRs of 12 (4.5%) males and 26 (5.4%) females. The CAC prevalence was not significantly different between the males and females (P=0.583). These calcifications were unilateral in 26 (68.4%) and bilateral in 12 (31.6%) subjects. Of those in the positive group, there were 12 subjects (31.58%) with hyperlipidemia, 12 subjects (31.58%) with hypertension, 7 subjects (18.4%) with diabetes mellitus, 6 subjects (15.8%) with cardiovascular disease, and 6 subjects (15.8%) with smoking history.Conclusions: This study has the highest CACs prevalence in comparison to the other studies. Therefore, dentists caring for subjects with dental problems should carefully evaluate their PRs for the evidence of CACs, and refer them for medical evaluation as indicated. So, incidental findings could provide life-saving information. (Eur J Dent 2007;1:132-138)


2000 ◽  
Vol 151 (1) ◽  
pp. 25-26
Author(s):  
H Nakano ◽  
K Okazaki ◽  
S Sato ◽  
T Suzuki ◽  
K Oba ◽  
...  

2015 ◽  
Vol 65 (10) ◽  
pp. A2095
Author(s):  
Adam D. Gepner ◽  
Laura Colangelo ◽  
Claudia Korcarz ◽  
Nicole Reilly ◽  
Joel Kaufman ◽  
...  

2021 ◽  
Vol 316 ◽  
pp. 8-14
Author(s):  
Frans Kauw ◽  
Pim A. de Jong ◽  
Richard A.P. Takx ◽  
Hugo W.A.M. de Jong ◽  
L. Jaap Kappelle ◽  
...  

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