scholarly journals Metabolic manipulation of the tumour immune microenvironment

Immunology ◽  
2021 ◽  
Author(s):  
Mengtian Wan ◽  
Yuzhu Ding ◽  
Zheng Li ◽  
Xu Wang ◽  
Min Xu
Keyword(s):  
Immune Microenvironment

Systematic evaluation of the immune microenvironment of neuroendocrine tumours

2017 ◽  
Author(s):  
Clare Vesely ◽  
Alexa Childs ◽  
Yien Ning Sophia Wong ◽  
Olagunju Ogunbiyi ◽  
Amir Gander ◽  
...  
Keyword(s):  
Neuroendocrine Tumours ◽  
Systematic Evaluation ◽  
Immune Microenvironment

NIR-active Nanoterminator with Mature Dendritic Cell Acitivities for Immuno-Priming Mild Photothermal Cancer Therapy

2020 ◽  
Author(s):  
zhihong sun ◽  
Guanjun Deng ◽  
Xinghua Peng ◽  
Xiuli Xu ◽  
Lanlan Liu ◽  
...  
Keyword(s):  
Dendritic Cell ◽  
Photothermal Therapy ◽  
Whole Body ◽  
Mature Dendritic Cell ◽  
Immune Microenvironment ◽  
Highly Efficient ◽  
Tumor Immune Microenvironment ◽  
Shock Proteins ◽  
Mild Temperature ◽  
Broad Interest

Recently, photothermal-immuno synergistic therapy under mild temperature (~ 45 °C) has got broad interest in cancer treatment. Inhibition the intratumorally HSPs production is the key to accomplish highly efficient and mild photothermal therapy. In this work, we developed biomimetic nanoterminators with mature DCs functions by coating the mature dendritic cell membrane on photothermal nanoagents. As-prepared nanoterminators could automatically locate on T cell in the complex tumor-immune microenvironment and promote the T cells proliferation, activation and cytokine secretion, which could not only inhibit the expression of heat shock proteins to cooperate on highly efficient mild photothermal therapy (~42°C), but also promote tumor apoptosis during the treatment. More importantly, this nanoterminator could serve as vaccine to trigger anti-tumor immune response of the whole body, which would be promising to long-life tumor inhibition and termination.

Bioinformatic Profiling of Prognosis-Related Genes in Breast Cancer Immune Microenvironment

2019 ◽  
Author(s):  
Fang Bai ◽  
Hongliang Chen ◽  
Yipeng Fu ◽  
Peng Zhang ◽  
Mingdi Zhang ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Immune Microenvironment

Impact of Stimulator of Interferon Genes (STING) Signaling on the Tumor Immune Microenvironment

2020 ◽  
Author(s):  
Ling-Ling Zhu ◽  
Ze-Long Liu ◽  
Jing-Hua Liu ◽  
Zi-han Qu ◽  
Hong-e Zhang ◽  
...  
Keyword(s):  
Immune Microenvironment ◽  
Tumor Immune Microenvironment

A pan-cancer analysis of the human tumor coagulome and its link to the tumor immune microenvironment

2020 ◽  
Author(s):  
Zuzana Saidak ◽  
Simon Soudet ◽  
Marine Lottin ◽  
Valéry Salle ◽  
Marie-Antoinette Sevestre ◽  
...  
Keyword(s):  
Human Tumor ◽  
Immune Microenvironment ◽  
Tumor Immune Microenvironment ◽  
Pan Cancer
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