scholarly journals Epidemiology and burden of illness of seasonal influenza among the elderly in Japan: A systematic literature review and vaccine effectiveness meta‐analysis

2020 ◽  
Author(s):  
Kiyosu Taniguchi ◽  
Shunya Ikeda ◽  
Yuriko Hagiwara ◽  
Daisuke Tsuzuki ◽  
Marwa Klai ◽  
...  
Keyword(s):  
Literature Review ◽  
Systematic Literature Review ◽  
Seasonal Influenza ◽  
Burden Of Illness ◽  
Meta Analysis ◽  
The Elderly ◽  
Vaccine Effectiveness

scholarly journals Influenza vaccine effectiveness among high-risk groups: A systematic literature review and meta-analysis of case-control and cohort studies

2017 ◽  
Vol 14 (3) ◽  
pp. 724-735 ◽  
Author(s):  
Vincenzo Restivo ◽  
Claudio Costantino ◽  
Stefania Bono ◽  
Marialuisa Maniglia ◽  
Valentina Marchese ◽  
...  
Keyword(s):  
High Risk ◽  
Literature Review ◽  
Influenza Vaccine ◽  
Cohort Studies ◽  
Systematic Literature Review ◽  
Meta Analysis ◽  
Risk Groups ◽  
Case Control ◽  
Vaccine Effectiveness

scholarly journals The short-term effectiveness of coronavirus disease 2019 (COVID-19) vaccines among healthcare workers: a systematic literature review and meta-analysis

2021 ◽  
Vol 1 (1) ◽  
Author(s):  
Alexandre R. Marra ◽  
Takaaki Kobayashi ◽  
Hiroyuki Suzuki ◽  
Mohammed Alsuhaibani ◽  
Bruna Marques Tofaneto ◽  
...  
Keyword(s):  
Literature Review ◽  
Systematic Literature Review ◽  
Healthcare Workers ◽  
Meta Analysis ◽  
Diagnostic Odds Ratio ◽  
Vaccine Effectiveness ◽  
Cochrane Central Register ◽  
Short Term ◽  
Central Register ◽  
Stratified Analysis

Abstract Objective: Healthcare workers (HCWs) are at risk of COVID-19 due to high levels of SARS-CoV-2 exposure. Thus, effective vaccines are needed. We performed a systematic literature review and meta-analysis on COVID-19 short-term vaccine effectiveness among HCWs. Methods: We searched PubMed, CINAHL, EMBASE, Cochrane Central Register of Controlled Trials, Scopus, and Web of Science from December 2019 to June 11, 2021, for studies evaluating vaccine effectiveness against symptomatic COVID-19 among HCWs. To meta-analyze the extracted data, we calculated the pooled diagnostic odds ratio (DOR) for COVID-19 between vaccinated and unvaccinated HCWs. Vaccine effectiveness was estimated as 100% × (1 − DOR). We also performed a stratified analysis for vaccine effectiveness by vaccination status: 1 dose and 2 doses of the vaccine. Results: We included 13 studies, including 173,742 HCWs evaluated for vaccine effectiveness in the meta-analysis. The vast majority (99.9%) of HCWs were vaccinated with the Pfizer/BioNTech COVID-19 mRNA vaccine. The pooled DOR for symptomatic COVID-19 among vaccinated HCWs was 0.072 (95% confidence interval [CI], 0.028–0.184) with an estimated vaccine effectiveness of 92.8% (95% CI, 81.6%–97.2%). In stratified analyses, the estimated vaccine effectiveness against symptomatic COVID-19 among HCWs who had received 1 dose of vaccine was 82.1% (95% CI, 46.1%–94.1%) and the vaccine effectiveness among HCWs who had received 2 doses was 93.5% (95% CI, 82.5%–97.6%). Conclusions: The COVID-19 mRNA vaccines are highly effective against symptomatic COVID-19, even with 1 dose. More observational studies are needed to evaluate the vaccine effectiveness of other COVID-19 vaccines, COVID-19 breakthrough after vaccination, and vaccine efficacy against new variants.

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