A multicentre, randomized, controlled study of the efficacy, safety and cost-effectiveness of a combination therapy with amorolfine nail lacquer and oral terbinafine compared with oral terbinafine alone for the treatment of onychomycosis with matrix involvement

2007 ◽  
Vol 157 (1) ◽  
pp. 149-157 ◽  
Author(s):  
R. Baran ◽  
B. Sigurgeirsson ◽  
D. de Berker ◽  
R. Kaufmann ◽  
M. Lecha ◽  
...  
2020 ◽  
Vol 46 (11) ◽  
pp. 2015-2025 ◽  
Author(s):  
Sung Yeon Hwang ◽  
◽  
Seung Mok Ryoo ◽  
Jong Eun Park ◽  
You Hwan Jo ◽  
...  

2018 ◽  
Vol 130 (7) ◽  
pp. 621-626 ◽  
Author(s):  
Uday Venkat Mateti ◽  
Anantha Naik Nagappa ◽  
Ravindra Prabhu Attur ◽  
Shankar Prasad Nagaraju ◽  
Dharshan Rangaswamy

2019 ◽  
Vol 39 (02) ◽  
pp. 133-142 ◽  
Author(s):  
Zubair Usman ◽  
Sonill Sooknunan Maharaj ◽  
Bashir Kaka

Background: Knee osteoarthritis (KOA) is a common degenerative articular disease that causes disability and poor quality of life (QoL) of the individuals. Electrotherapeutic agents such as therapeutic ultrasound (US), interferential current (IFC), and infrared radiation are used in the treatment. It is not clear which of these agents is the best in improving these variables.Objective: The study aimed to compare the effects of the combined application of US and IFC therapies and infrared radiation on pain, functional activities, and QoL in people with KOA.Methods: In a randomized controlled study, 60 participants were randomized into two groups, the combination therapy group (CTG) and the infrared radiation group (IRG). Each group received 15-min treatment three times per week for 12 weeks. The visual analog scale (VAS) was used to assess the pain, Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) for functional activities and the Short Form Health Survey questionnaire for QoL.Results: Participants in the CTG had a significant ([Formula: see text]) reduction in pain and significant ([Formula: see text]) improvement in functional activities and QoL compared to the IRG.Conclusion: The results of this study support the use of the combination of IFC and US therapies to reduce pain and improve function and QoL for KOA patients.


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