Hepatitis E virus infection in patients from Saudi Arabia with sickle cell anaemia and β-thalassemia major: possible transmission by blood transfusion

1996 ◽  
Vol 3 (4) ◽  
pp. 203-205 ◽  
Author(s):  
I. Al-Fawaz ◽  
S. Al-Rasheed ◽  
M. Al-Mugeiren ◽  
A. Al-Salloum ◽  
M. Al-Sohaibani ◽  
...  
2021 ◽  
Author(s):  
Bader Y Alhatlani ◽  
Waleed A Aljabr ◽  
Mohammed S Almarzouqi ◽  
Sami M Alhatlani ◽  
Rayan N Alzunaydi ◽  
...  

Aim: Hepatitis E virus (HEV) transmission through blood transfusion is a major public health issue worldwide. We aimed to determine the seroprevalence of HEV in blood donors in the Qassim region of Saudi Arabia. Materials & methods: Serum samples (n = 1078) were collected from volunteer blood donors and tested for the presence of anti-HEV IgG and IgM by indirect ELISA. Results: The seroprevalence of anti-HEV IgG among the blood donors was 5.7% overall. Anti-HEV IgG and IgM seropositivity were significantly higher in non-Saudi donors than in Saudi donors (22.1 vs 3 and 7.8 vs 0.2% for anti-HEV IgG and IgM, respectively). Conclusion: The seroprevalence of HEV among blood donors in the Qassim region was lower than previous estimates for other regions of the country and neighboring countries.


2020 ◽  
Author(s):  
Bader Alhatlani ◽  
Waleed Aljabr ◽  
Mohammed Almarzouqi ◽  
Sami Alhatlani ◽  
Rayan Alzunaydi ◽  
...  

Abstract Objectives The aim of this study was to evaluate the seroprevalence of hepatitis E virus (HEV), a major public health issue worldwide with the potential for transmission via blood transfusion, in blood donors in the Qassim Region, Saudi Arabia. Serum samples (n = 1,078) were collected from volunteer blood donors from January to April 2019 and tested for the presence of anti-HEV IgG and IgM by indirect enzyme-linked immunosorbent assays. Results Overall, the seroprevalence of anti-HEV IgG and IgM among blood donors was 5.7% and 1.3%, respectively. Additionally, the seropositive rates of anti-HEV IgG and IgM were significantly higher in non-Saudi donors (22.1% and 7.8%) than in Saudi donors (3% and 0.2%). The seroprevalence of anti-HEV IgG increased with age; however, there was no correlation between gender and anti-HEV IgG and/or IgM. The seroprevalence of HEV among blood donors in the Qassim Region was lower than previous estimates for other regions of the country. Further studies covering a wider geographical area are needed to validate and expand the findings and to determine the importance of HEV screening in the region.


2002 ◽  
Vol 66 (3) ◽  
pp. 329-334 ◽  
Author(s):  
E.A. Ayoola ◽  
M.A. Want ◽  
M.O.E.H. Gadour ◽  
M.H. Al-Hazmi ◽  
M.K.M. Hamza

2004 ◽  
Vol 74 (4) ◽  
pp. 563-572 ◽  
Author(s):  
Takehiro Mitsui ◽  
Yukie Tsukamoto ◽  
Chikao Yamazaki ◽  
Kazuo Masuko ◽  
Fumio Tsuda ◽  
...  

2019 ◽  
Vol 91 (9) ◽  
pp. 1693-1697
Author(s):  
Svetoslav N. Slavov ◽  
Juliana D. M. Maçonetto ◽  
Edson Z. Martinez ◽  
Ana Cristina Silva‐Pinto ◽  
Dimas T. Covas ◽  
...  

2011 ◽  
Vol 6 (2) ◽  
pp. 344-349 ◽  
Author(s):  
K. Matsubayashi ◽  
H. Sakata ◽  
H. Ikeda

2021 ◽  
Vol Volume 14 ◽  
pp. 2381-2390
Author(s):  
Reem A Al Dossary ◽  
Awatif N AlNafie ◽  
Salma Ali Aljaroodi ◽  
Jawad Ur Rahman ◽  
Basavaraj C Hunasemarada ◽  
...  

2020 ◽  
Author(s):  
Bader Alhatlani ◽  
Waleed Aljabr ◽  
Mohammed Almarzouqi ◽  
Sami Alhatlani ◽  
Rayan Alzunaydi ◽  
...  

Abstract ObjectivesTo evaluate the seroprevalence of hepatitis E virus (HEV), a major public health issue worldwide with the potential for transmission via blood transfusion, in blood donors in the Qassim Region, Saudi Arabia. Serum samples (n = 1,078) were collected from volunteer blood donors from January to April 2019 and tested for the presence of anti-HEV IgG and IgM by indirect enzyme-linked immunosorbent assays.ResultsOverall, the seroprevalence of anti-HEV IgG among blood donors was 5.7%. Additionally, the seropositive rates of anti-HEV IgG and IgM were significantly higher in non-Saudi donors (22.1% and 35.3%) than in Saudi donors (3% and 7.4%). The seroprevalence of anti-HEV IgG increased with age; however, there was no correlation between gender and anti-HEV IgG and/or IgM. The seroprevalence of HEV among blood donors in the Qassim Region was lower than previous estimates for other regions of the country. Further studies covering a wider geographical area are needed to validate and expand the findings and to determine the importance of HEV screening in the region.


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