Early rapid weight gain and current overweight in relation to asthma in adolescents born with very low birth weight

2005 ◽  
Vol 16 (5) ◽  
pp. 380-385 ◽  
Author(s):  
Xiao-Mei Mai ◽  
Per-Olof Gaddlin ◽  
Lennart Nilsson ◽  
Ingemar Leijon
2008 ◽  
Vol 46 (1) ◽  
pp. 113-116 ◽  
Author(s):  
Juliane Spiegler ◽  
Evelyn Kattner ◽  
Matthias Vochem ◽  
Helmuth Küster ◽  
Jens Möller ◽  
...  

2013 ◽  
Vol 30 (10) ◽  
pp. 863-870 ◽  
Author(s):  
Emily Zimmerman ◽  
Kristin Keunen ◽  
Melanie Norton ◽  
Amir Lahav

2018 ◽  
Vol 107 (2) ◽  
pp. 195-200 ◽  
Author(s):  
Laura Morlacchi ◽  
Paola Roggero ◽  
Maria Lorella Giannì ◽  
Beatrice Bracco ◽  
Debora Porri ◽  
...  

2020 ◽  
Author(s):  
Il Tae Hwang ◽  
Young-Su Ju ◽  
Hye Jin Lee ◽  
Young Suk Shim ◽  
Hwal Rim Jeong ◽  
...  

AbstractPurposeWe analyzed the nationwide longitudinal data to explore body mass index (BMI) growth trajectories and the time of adiposity rebound (AR).MethodsPersonal data of 84,005 subjects born between 2008 and 2012 were obtained from infant health check-ups which were performed at 5, 11, 21, 33, 45, 57, and 69 months. BMI 00trajectories of each subject were made according to sex and birth weight (Bwt) and the timing of AR was defined as the lowest BMI occurred. Subjects were divided according to Bwt and AR timing as follows: very low birth weight (VLBW), 0.5 kg ≤ Bwt ≤ 1.5 kg; low birth weight (LBW), 1.5 kg < Bwt ≤ 2.5 kg; non-LBW, 2.5 kg < Bwt ≤ 5.0 kg; early AR, before 45 months; moderate AR, at 57 months; and late AR, not until 69 months.Main resultsMedian time point of minimum BMI was 45 months, and the prevalence rates of early, moderate, and late AR were 63.0%, 16.6%, and 20.4%, respectively. BMI at the age of 57 months showed a strong correlation with AR timing after controlling for Bwt (P < 0.001). Sugar-sweetened beverage intake at 21 months (P = 0.02) and no-exercise habit at 57 months (P < 0.001) showed correlations with early AR. When VLBW and LBW subjects were analyzed, BMI at 57 months and breastfeeding at 11 months were correlated with rapid weight gain during the first 5 months (both P < 0.001).ConclusionsBased on this first longitudinal study, the majority of children showed AR before 57 months and the degree of obesity at the age of 57 months had a close correlation with early AR or early weight during infancy.


2016 ◽  
Vol 19 (1) ◽  
pp. 36-44 ◽  
Author(s):  
Kelley L. Baumgartel ◽  
Maureen W. Groer ◽  
Susan M. Cohen ◽  
Dianxu Ren ◽  
Diane L. Spatz ◽  
...  

Background: Maternal interleukin (IL) single nucleotide polymorphisms (SNPs) are associated with obstetrical outcomes. Conversely, infant SNPs are associated with subsequent neonatal intensive care unit (NICU) outcomes. Little is known about relationships between maternal SNPs and neonatal outcomes. Purpose: To examine the relationships between maternal IL genotypes and neonatal outcomes. Methods: An ancillary study was conducted among mothers ( N = 63) who delivered very low-birth-weight infants ( N = 74). Maternal DNA was extracted from breast milk and genotyped. Outcomes included fecal calprotectin, length of stay, scores for neonatal acute physiology with perinatal extension (SNAPPE-II), weight gain, oxygen needs, necrotizing enterocolitis, intraventricular hemorrhage, sepsis, retinopathy of prematurity, blood transfusions, and feeding intolerance. Multivariate analyses examined the relationships between maternal IL SNPs and outcomes, controlling for gestational age and the ratio of maternal milk to total milk. Results: Absence of a minor allele in 2 IL6 SNPs was associated with fecal calprotectin ( p = .0222, p = .0429), length of stay ( p = .0158), SNAPPE-II ( p = .0497), weight gain ( p = .0272), and days on oxygen ( p = .0316). IL6 genotype GG (rs1800795) was associated with length of stay ( p = .0034) and calprotectin ( p = .0213). Minor-allele absence in 2 IL10 SNPs was associated with days on oxygen ( p = .0320). There were associations between IL10 genotype TT (rs1800871) and calprotectin ( p = .0270) and between IL10 genotypes AA (rs1800872 and rs1800896) and calprotectin ( p = .0158, p = .0045). Conclusion: Maternal IL SNPs are associated with NICU outcomes. A potential clinical application includes an antenatal risk profile to identify neonatal needs.


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