Some Observations on D Antigen Expression of D-Positive and ‘Weak D-Positive’ Red Cells as Assessed by Flow Cytometry

Vox Sanguinis ◽  
1995 ◽  
Vol 69 (2) ◽  
pp. 154-154
Author(s):  
Pier Luigi Tazzari ◽  
Andrea Bontadini ◽  
Daniela Belletti ◽  
Franco Malferrari ◽  
Roberto Conte
Keyword(s):  
Flow Cytometry ◽  
Antigen Expression ◽  
Red Cells ◽  
D Antigen

Some Observations on D Antigen Expression of D-Positive and ‘Weak D-Positive’ Red Cells as Assessed by Flow Cytometry

Vox Sanguinis ◽  
1995 ◽  
Vol 69 (2) ◽  
pp. 152-153 ◽  
Author(s):  
M. Nelson ◽  
L.A. Barrow ◽  
H. Popp ◽  
J. Gibson
Keyword(s):  
Flow Cytometry ◽  
Antigen Expression ◽  
Red Cells ◽  
D Antigen

Some Observations on D Antigen Expression of D-Positive and 'Weak D-Positive' Red Cells as Assessed by Flow Cytometry

Vox Sanguinis ◽  
1995 ◽  
Vol 69 (2) ◽  
pp. 154-154
Author(s):  
Pier Luigi Tazzari ◽  
Andrea Bontadini ◽  
Daniela Belletti ◽  
Franco Malferrari ◽  
Roberto Conte
Keyword(s):  
Flow Cytometry ◽  
Antigen Expression ◽  
Red Cells ◽  
D Antigen

Some Observations on D Antigen Expression of D-Positive and 'Weak D-Positive' Red Cells as Assessed by Flow Cytometry

Vox Sanguinis ◽  
1995 ◽  
Vol 69 (2) ◽  
pp. 152-153
Author(s):  
M. Nelson ◽  
L.A. Barrow ◽  
H. Popp ◽  
J. Gibson
Keyword(s):  
Flow Cytometry ◽  
Antigen Expression ◽  
Red Cells ◽  
D Antigen

Quantitation of Rh D Antigen Sites on Weak D and D Variant Red Cells by Flow Cytometry

Vox Sanguinis ◽  
1996 ◽  
Vol 71 (3) ◽  
pp. 176-183 ◽  
Author(s):  
J. W. Jones ◽  
P. Loyd-Evans ◽  
B. M. Kumpel
Keyword(s):  
Flow Cytometry ◽  
Red Cells ◽  
D Antigen

Quantitation of Rh D Antigen Sites on Weak D and D Variant Red Cells by Flow Cytometry

Vox Sanguinis ◽  
1996 ◽  
Vol 71 (3) ◽  
pp. 176-183 ◽  
Author(s):  
J.W. Jones ◽  
P. Lloyd-Evans ◽  
B.M. Kumpel
Keyword(s):  
Flow Cytometry ◽  
Red Cells ◽  
D Antigen

Aberrant Expression of CD Markers in Acute Myeloid Leukaemia

2018 ◽  
Vol 2 (01) ◽  
pp. 14-16
Author(s):  
Abul Kalam Azad ◽  
Md. Rafiquzzaman Khan ◽  
ABM Hasan Habib ◽  
Md. Abdul Wadud Miah ◽  
Masuda Begum
Keyword(s):  
Flow Cytometry ◽  
Acute Myeloid Leukaemia ◽  
Myeloid Leukaemia ◽  
Acute Leukaemia ◽  
Antigen Expression ◽  
Aberrant Expression ◽  
Female Ratio ◽  
Cd Antigen ◽  
Cd Markers ◽  
Acute Myeloid

Background: Aberrant expression of cluster differentiation (CD) antigen marker is associated with poor outcome of acute leukaemia. Objective: Aim of this study is to determine the frequency and pattern of aberrant expression of CD markers in acute myeloid leukaemia patients in Bangladesh. Methods: This retrospective data analysis was conducted in the Department of Haematology, Bangabandhu Sheikh Mujib Medical University (BSMMU) to assess the frequency of aberrant CD antigen expression in acute myeloid leukaemia from October 2016 to September 2017. During this period, we did one hundred flow cytometry of acute leukaemia patients and among them we found 48 acute myeloid Leukaemia (AML) who were included in this study. Result: Mean age of patients was 35 years (SD­ +14 years; Rang 3 to 50 years) with male: female ratio of 0.92. Four colour flow cytometry was done on fresh bone marrow aspirates and peripheral blood. Among 48 AML patients, aberrant CD expression was observed in 58% cases.  CD5 and cCD79a lymphoid markers were seen to be expressed in 32% cases of AML. Aberrant cCD3 and CD7 were expressed in 29% and 25% cases respectively and aberrant CD10, CD19, cCD22 were expressed in 11%, 3%, 3% cases acute myeloid leukaemia patients respectively. Conclusion: Aberrant CD antigen expression is not uncommon in AML patients of Bangladeshi population that may adversely affect the treatment outcome of the disease.

scholarly journals Missense RHD single nucleotide variants induce weakened D antigen expression by altering splicing and/or protein expression

Transfusion ◽  
2021 ◽  
Author(s):  
Loann Raud ◽  
Marlène Le Tertre ◽  
Léonie Vigneron ◽  
Chandran Ka ◽  
Gaëlle Richard ◽  
...  
Keyword(s):  
Protein Expression ◽  
Antigen Expression ◽  
Single Nucleotide Variants ◽  
Single Nucleotide ◽  
D Antigen

Variation in the level of Rh(D) antigen expression

Transfusion ◽  
1988 ◽  
Vol 28 (4) ◽  
pp. 397-398 ◽  
Author(s):  
AH Merry ◽  
C Hodson ◽  
S Moore
Keyword(s):  
Antigen Expression ◽  
D Antigen

Increased Fraction of Circulating Activated Platelets in Acute and Previous Cerebrovascular Ischemia

1998 ◽  
Vol 80 (08) ◽  
pp. 298-301 ◽  
Author(s):  
Andreas Ruf ◽  
Axel Vogt ◽  
Christoph Lichy ◽  
Florian Buggle ◽  
Heinrich Patscheke ◽  
...  
Keyword(s):  
Flow Cytometry ◽  
Phase Contrast ◽  
Matched Control ◽  
Shape Change ◽  
Antigen Expression ◽  
Phase Contrast Microscopy ◽  
Activated Platelets ◽  
Contrast Microscopy ◽  
Age And Sex

SummaryDetermination of circulating activated platelets may be helpful to estimate the prognosis and to stratify therapies in arterial vascular disorders including stroke. We used flow cytometry and phase contrast microscopy to study whether the fraction of platelets expressing p-selectin and CD63 and the fraction of platelets with shape change are increased in patients with acute and previous cerebrovascular ischemia.The proportion of platelets expressing activation dependent antigens was higher in patients with acute (n = 24; p-selectin: 8.23 ± 4.21%; CD63: 3.53 ± 2.53%) and with previous cerebrovascular ischemia (n = 46; 3.86 ± 1.98%; 2.80 ± 1.79%) as compared to age- and sex-matched control subjects (n = 35; 2.17 ± 0.96%; 1.79 ± 0.75%; p ≤0.005, respectively). In patients with previous ischemia, there was no difference between treatment with aspirin (n = 25) or phenprocoumon (n = 21). Hypertension, diabetes mellitus and smoking were not associated with increased antigen expression (analysis of variance). The fraction of discoid platelets and platelet counts were not significantly different between groups.Our results indicate increased expression of platelet neoantigens in acute and to a less degree in previous cerebrovascular ischemia. Ongoing platelet activation after cerebrovascular ischemia despite therapy with aspirin or phenprocoumon indicates that new anti-platelet drugs may be of benefit for these patients. Flow cytometry appears to be a useful tool to assess platelet function in cerebrovascular ischemia.

Weak D antigen expression caused by a novelRHDallele in Argentineans

Transfusion ◽  
2016 ◽  
Vol 56 (11) ◽  
pp. 2895-2896 ◽  
Author(s):  
Carolina Trucco Boggione ◽  
Melina Eliana Luján Brajovich ◽  
Ane Caroline Gaspardi ◽  
Emilia Sippert ◽  
Stella Maris Mattaloni ◽  
...  
Keyword(s):  
Antigen Expression ◽  
D Antigen
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