scholarly journals The iron-sulfur clusters in the two related forms of mitochondrial NADH: ubiquinone oxidoreductase made by Neurospora crassa

1991 ◽  
Vol 197 (1) ◽  
pp. 257-264 ◽  
Author(s):  
Da-Cheng WANG ◽  
Steven W. MEINHARDT ◽  
Uwe SACKMANN ◽  
Hanns WEISS ◽  
Tomoko OHNISHI
Keyword(s):  
Neurospora Crassa ◽  
Iron Sulfur Clusters ◽  
Ubiquinone Oxidoreductase ◽  
Iron Sulfur ◽  
Nadh Ubiquinone Oxidoreductase

The membrane domain of complex I is not assembled in the stopper mutant E35 of Neurospora

1998 ◽  
Vol 76 (1) ◽  
pp. 139-143 ◽  
Author(s):  
Paulo Caseiro Alves ◽  
Arnaldo Videira
Keyword(s):  
Neurospora Crassa ◽  
Complex I ◽  
Growth Period ◽  
Membrane Domain ◽  
Liquid Media ◽  
Ubiquinone Oxidoreductase ◽  
Nadh Ubiquinone Oxidoreductase ◽  
Mitochondria Complex I ◽  
Specific Deletion

The assembly of mitochondrial NADH : ubiquinone oxidoreductase (complex I) was studied in the E35 stopper mutant of Neurospora crassa at different times during growth in liquid media. Assembly of complex I as well as of its membrane domain is impaired in this strain throughout the growth period. Nevertheless, a structure that resembles the peripheral arm of the enzyme is still formed in the mitochondria of this mutant. The absence of the membrane domain of complex I in E35 can be attributed to the specific deletion of the mitochondrial ND2 and ND3 subunits of the enzyme.Key words: mitochondria, complex I, stopper mutants, Neurospora crassa.

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