Scavenging effect of N-acetyl-L-cysteine against reactive oxygen species in human semen: a possible therapeutic modality for male factor infertility?

Andrologia ◽  
2009 ◽  
Vol 29 (3) ◽  
pp. 125-131 ◽  
Author(s):  
T. Oeda ◽  
R. Henkel ◽  
H. Ohmori ◽  
W.-B. Schill
Keyword(s):  
Reactive Oxygen Species ◽  
Reactive Oxygen ◽  
Therapeutic Modality ◽  
Oxygen Species ◽  
Male Factor Infertility ◽  
Human Semen ◽  
Male Factor ◽  
Scavenging Effect

Reactive oxygen species as an independent marker of male factor infertility

2006 ◽  
Vol 86 (4) ◽  
pp. 878-885 ◽  
Author(s):  
A AGARWAL ◽  
R SHARMA ◽  
K NALLELLA ◽  
A THOMASJR ◽  
J ALVAREZ ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Reactive Oxygen ◽  
Oxygen Species ◽  
Male Factor Infertility ◽  
Male Factor ◽  
Independent Marker

Reactive Oxygen Species in Human Semen: Investigations and Measurements

1998 ◽  
Vol 40 (1) ◽  
pp. 67-78 ◽  
Author(s):  
U.-C. Hipler ◽  
G. Schreiber ◽  
U. Wollina
Keyword(s):  
Reactive Oxygen Species ◽  
Reactive Oxygen ◽  
Oxygen Species ◽  
Human Semen

scholarly journals Origin of reactive oxygen species in human semen: spermatozoa or leucocytes?

Reproduction ◽  
1992 ◽  
Vol 94 (2) ◽  
pp. 463-470 ◽  
Author(s):  
E. Kessopoulou ◽  
M. J. Tomlinson ◽  
C. L. R. Barratt ◽  
A. E. Bolton ◽  
I. D. Cooke
Keyword(s):  
Reactive Oxygen Species ◽  
Reactive Oxygen ◽  
Oxygen Species ◽  
Human Semen

A Method of Human Semen Centrifugation to Minimize the Iatrogenic Sperm Injuries Caused by Reactive Oxygen Species

1995 ◽  
Vol 28 (1) ◽  
pp. 31-35 ◽  
Author(s):  
Mohammad Shekarriz ◽  
D.M. DeWire ◽  
Anthony J. Thomas, Jr. ◽  
Ashok Agarwal
Keyword(s):  
Reactive Oxygen Species ◽  
Reactive Oxygen ◽  
Oxygen Species ◽  
Human Semen

scholarly journals REACTIVE OXYGEN SPECIES IN HUMAN SEMEN IN RELATION TO LEUKOCYTE CONTAMINATION

2009 ◽  
Vol 153 (1) ◽  
pp. 53-57 ◽  
Author(s):  
Ivana Oborna ◽  
Helena Fingerova ◽  
Jiri Novotny ◽  
Jana Brezinova ◽  
Magda Svobodova ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Reactive Oxygen ◽  
Oxygen Species ◽  
Human Semen

Intracellular reactive oxygen species scavenging effect of fucosterol isolated from the brown alga Sargassum crassifolium in Vietnam

2020 ◽  
Vol 20 (3) ◽  
pp. 308-316
Author(s):  
Hoang Kim Chi ◽  
Le Huu Cuong ◽  
Nguyen Thi Hong Van ◽  
Tran Thi Nhu Hang ◽  
Do Huu Nghi ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Therapeutic Potential ◽  
Reactive Oxygen ◽  
Intracellular Reactive Oxygen Species ◽  
Bioactive Metabolites ◽  
Chemical Fractionation ◽  
Oxygen Species ◽  
Vitro Assay ◽  
Scavenging Effect ◽  
South Central

Sargassum is a widely distributed marine brown algal genus in Vietnam and has been considered a source of diverse bioactive metabolites. In this study, S. crassifolium collected from South Central region of Vietnam was chemically studied and bioactively evaluated. Fucosterol was isolated and identified from the methanolic extract of the alga by means of chemical fractionation and spectral analysis and showed no cytotoxic effect in Hep-G2 cells at the observed concentrations. In vitro assay for intracellular reactive oxygen species by dichlorofluorescein method revealed a potent scavenging effect of the isolated compound. Accordingly, the level of intracellular reactive oxygen species induced by hydrogen peroxide (H2O2) was reduced by 71.66% with the treatment of fucosterol at 10 µg.ml-1. The results indicated the ability of algal fucosterol in diffusing into cells and preventing the production of different ROS compounds and further suggested the therapeutic potential against diseases caused by oxidative stress of natural metabolites from S. crassifolium in Vietnam.

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