PRIMARY LOW-GRADE B CELL LYMPHOMA OF MUCOSA-ASSOCIATED LYMPHOID TISSUE TYPE OF THE COMMON BILE DUCT

2008 ◽  
Vol 16 (8) ◽  
pp. 949-951
Author(s):  
CS Kang ◽  
YS Lee ◽  
SM Kim ◽  
BK Kim
1996 ◽  
Vol 20 (8) ◽  
pp. 1011-1023 ◽  
Author(s):  
Elizabeth M. Bailey ◽  
Judith A. Ferry ◽  
Nancy L. Harris ◽  
Martin C. Mihm ◽  
Joseph O. Jacobson ◽  
...  

2008 ◽  
pp. ???-??? ◽  
Author(s):  
Hideko Yamamoto ◽  
Tsuneya Nakamura ◽  
Keitaro Matsuo ◽  
Masahiro Tajika ◽  
Hiroki Kawai ◽  
...  

2002 ◽  
Vol 93 (6) ◽  
pp. 677-684 ◽  
Author(s):  
Tsuneya Nakamura ◽  
Shigeo Nakamura ◽  
Takio Yokoi ◽  
Hiroko Suzuki ◽  
Kazuhiko Ohashi ◽  
...  

2020 ◽  
Vol 24 (10) ◽  
pp. 2376-2378 ◽  
Author(s):  
Denise L. Wong ◽  
Benjamin W. Deschner ◽  
Lauren C. King ◽  
Evan S. Glazer

Blood ◽  
1995 ◽  
Vol 86 (9) ◽  
pp. 3528-3534 ◽  
Author(s):  
Y Qin ◽  
A Greiner ◽  
MJ Trunk ◽  
B Schmausser ◽  
MM Ott ◽  
...  

The origin of low-grade mucosa-associated lymphoid tissue (MALT)-type B- cell lymphoma is still unclear. Using a novel two-step procedure, we have sequenced the Ig VH genes expressed by cells from four patients with gastric low-grade MALT-type lymphoma. The nucleotide sequences of the complementarity determining region 3 (CDR3) of the genomic DNA were first amplified using consensus oligonucleotide primers, then sequenced. Based on the CDR3 sequence amplified from each MALT lymphoma, individual tumor-specific primers were synthesized and used directly in the polymerase chain reaction (PCR) to analyze the sequences of their Ig heavy-chain variable region. When compared with the germ-line sequence, many nucleotide substitutions, mainly in the CDRs, were found in the variable gene sequences of the four MALT lymphomas. The mutations showed a high replacement-to-silent ratio and were distributed in a way which suggested that the tumor cells had been positively selected through their antigen receptor. Our findings indicate that the MALT-type lymphoma B cells are hypermutated postgerminal center lymphocytes that have undergone antigen selection.


2015 ◽  
Vol 5 (2) ◽  
pp. 107-112 ◽  
Author(s):  
Hiroaki Kato ◽  
Masanori Tsujie ◽  
Tomoko Wakasa ◽  
Shuhei Kogata ◽  
Hirofumi Kanaizumi ◽  
...  

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