Hepatic natural killer and natural killer T cells markedly decreased in two cases of drug-induced fulminant hepatic failure rescued by living donor liver transplantation

2005 ◽  
Vol 20 (7) ◽  
pp. 1126-1130 ◽  
Author(s):  
RYOKO MIYAKAWA ◽  
TAKAFUMI ICHIDA ◽  
SATOSHI YAMAGIWA ◽  
CHIKAKO MIYAJI ◽  
HISAMI WATANABE ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
T Cells ◽  
Natural Killer ◽  
Living Donor ◽  
Living Donor Liver Transplantation ◽  
Natural Killer T Cells ◽  
Donor Liver ◽  
Drug Induced ◽  
Donor Liver Transplantation ◽  
Killer T Cells

scholarly journals A Mortality Case Caused by Thrombotic Microangiopathy after Successful Bloodless Living Donor Liver Transplantation

2021 ◽  
Vol 27 (2) ◽  
pp. 85-87
Author(s):  
Sun Young Park ◽  
Ho Bum Cho ◽  
Gyu Wan You ◽  
Kyeong Sik Kim
Keyword(s):  
Liver Transplantation ◽  
Thrombotic Microangiopathy ◽  
Living Donor ◽  
Living Donor Liver Transplantation ◽  
Solid Organ Transplantation ◽  
Clinical Manifestations ◽  
Solid Organ ◽  
Donor Liver ◽  
Drug Induced ◽  
Donor Liver Transplantation

Thrombotic microangiopathy (TMA) after solid organ transplantation is infrequent and its etiology remains still unclear. Nevertheless, if early diagnosis and early therapies are not performed, it can lead to severe life-threatening complications and even death. A 54-year-old female (a Jehovah’s Witness) was diagnosed with drug-induced toxic hepatitis and was decided to undergo bloodless living donor liver transplantation (LDLT). After the successful LDLT, the patient’s condition deteriorated, and she was diagnosed with TMA during further evaluation. We tried to proceed with plasma exchange-based treatment, but she and her family declined according to their religious beliefs. The patient expired 4 days after the diagnosis. Physicians should maintain a high level of suspicion for TMA after liver transplantation when clinical manifestations are observed.

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