Comparison of patient acceptance of sodium phosphate versus polyethylene glycol plus sodium picosulfate for colon cleansing in Japanese

2012 ◽  
Vol 27 (10) ◽  
pp. 1617-1622 ◽  
Author(s):  
Naoki Hosoe ◽  
Manabu Nakashita ◽  
Hiroyuki Imaeda ◽  
Tomohisa Sujino ◽  
Rieko Bessho ◽  
...  
Keyword(s):  
Polyethylene Glycol ◽  
Sodium Phosphate ◽  
Patient Acceptance ◽  
Colon Cleansing ◽  
Sodium Picosulfate

scholarly journals A Randomized Prospective Study of Bowel Preparation for Colonoscopy with Low-Dose Sodium Phosphate Tablets versus Polyethylene Glycol Electrolyte Solution

2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Erina Kumagai ◽  
Tomoyoshi Shibuya ◽  
Masae Makino ◽  
Takashi Murakami ◽  
Shiori Takashima ◽  
...  
Keyword(s):  
Polyethylene Glycol ◽  
Bowel Preparation ◽  
Low Dose ◽  
Patient Acceptance ◽  
Colon Cleansing ◽  
Bowel Cleansing ◽  
Secondary Endpoints ◽  
Tablet Preparation ◽  
Sodium Phosphates ◽  
Improve Patient

Optimal bowel preparation is essential for the safety and outcome of colonoscopy. A solution containing polyethylene glycol (PEG) is often used as a bowel cleansing agent, but some patients are intolerant of PEG, and this may lead to discontinuation of colonoscopy. Sodium phosphates (NaP) tablets are designed to improve patient acceptance and compliance. The objective of this study was to compare bowel preparation efficiency and patient acceptance of a 30 NaP tablet preparation (L-NaP) and a 2 L PEG preparation. Patients were randomized into either the L-NaP or PEG group. The primary endpoint was the efficiency of colon cleansing as assessed by a validated four-point scale according to the Aronchick scale by endoscopists and was verified by blinded investigators. The secondary endpoints were patients’ tolerability and acceptance. Colon-cleansing efficiency was not significantly different between the two preparations. However, patients’ overall judgment was significantly in favor of L-NaP, reflecting better acceptance of L-NaP than PEG. Additionally, more patients favored L-NaP over PEG in a hypothetical future occasion requiring colonoscopy.

Tolerability and Patient Acceptance of Sodium Phosphate Tablets Compared With 4-L PEG Solution in Colon Cleansing

2007 ◽  
Vol 41 (1) ◽  
pp. 54-61 ◽  
Author(s):  
David Kastenberg ◽  
Charles Barish ◽  
Harry Burack ◽  
Douglas Dean Dalke ◽  
Steven Duckor ◽  
...  
Keyword(s):  
Sodium Phosphate ◽  
Patient Acceptance ◽  
Colon Cleansing

scholarly journals Changes in Renal Function Following Administration of Oral Sodium Phosphate or Polyethylene Glycol for Colon Cleansing before Colonoscopy

2007 ◽  
Vol 21 (4) ◽  
pp. 227-231 ◽  
Author(s):  
Ramy Abaskharoun ◽  
William Depew ◽  
Stephen Vanner
Keyword(s):  
Renal Failure ◽  
Renal Function ◽  
Polyethylene Glycol ◽  
Sodium Phosphate ◽  
Renal Damage ◽  
Absolute Difference ◽  
Comorbid Conditions ◽  
Colon Cleansing ◽  
Oral Sodium Phosphate ◽  
Oral Sodium

Changes in renal function were compared in patients receiving oral sodium phosphate (NaP) for colon cleansing and those receiving large-volume polyethylene glycol (PEG) solution to determine whether oral NaP resulted in frequent renal damage that had gone clinically undetected. From 1995 to 2004, a cohort of consecutive patients who had serum creatinine (Cr) drawn immediately before colonoscopy and again after subsequent procedures three months to nine years later (almost 80% of patients between the first and fifth year) were identified. Chronic renal failure (CRF) was defined as an abnormal Cr at repeat measurement or an abnormal Cr clearance as estimated by the Cockroft-Gault equation at the time of repeat Cr measurement. Medications and medical comorbid conditions were recorded. Seven hundred sixty-seven patients (51% female and 49% male; 81% oral NaP and 19% PEG) with normal baseline Cr levels were identified through the endoscopy unit database at the Hotel Dieu Hospital, Queen’s University (Kingston, Ontario). Of these, 55 (7%) developed CRF. Forty-two (6.8%) patients receiving oral NaP developed renal failure compared with 13 patients (8.7%) receiving PEG (Fisher’s exact test; P=0.382), but the magnitude of CRF was small in each group (Cr level lower than 160 μmol/L). Using logistic regression analysis with the choice of preparation, medications and medical comorbid conditions as independent variables, only age and blood pressure were predictive of the development of renal failure (P=0.014 and P=0.001, respectively). Baseline Cr clearance was similiar in both the NaP and PEG groups and the absolute difference after colonoscopy did not differ. The present study concluded that the ingestion of oral NaP for colon cleansing before colonoscopy did not result in frequent renal damage that went clinically undetected.

Oral sodium phosphate versus sulfate-free polyethylene glycol electrolyte lavage solution in outpatient preparation for colonoscopy: a prospective comparison

1996 ◽  
Vol 43 (1) ◽  
pp. 42-48 ◽  
Author(s):  
Wendell K. Clarkston ◽  
Tony N. Tsen ◽  
David F. Dies ◽  
C.Lynn Schratz ◽  
Surender K. Vaswani ◽  
...  
Keyword(s):  
Polyethylene Glycol ◽  
Sodium Phosphate ◽  
Prospective Comparison ◽  
Oral Sodium Phosphate ◽  
Lavage Solution ◽  
Oral Sodium
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