scholarly journals Unmet needs of people with end-stage chronic obstructive pulmonary disease: recommendations for change in Australia

2013 ◽  
Vol 43 (2) ◽  
pp. 183-190 ◽  
Author(s):  
G. B. Crawford ◽  
M. A. Brooksbank ◽  
M. Brown ◽  
T. A. Burgess ◽  
M. Young
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Unmet Needs ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
End Stage

scholarly journals From Biomarkers to Novel Therapeutic Approaches in Chronic Obstructive Pulmonary Disease

Biomedicines ◽  
2021 ◽  
Vol 9 (11) ◽  
pp. 1638
Author(s):  
Hsu-Hui Wang ◽  
Shih-Lung Cheng
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Unmet Needs ◽  
Chronic Obstructive ◽  
Biological Therapies ◽  
Therapeutic Approaches ◽  
Comprehensive Overview ◽  
Obstructive Pulmonary Disease ◽  
Complex Disorder ◽  
Treatment Support

Chronic obstructive pulmonary disease (COPD) is a heterogeneous and complex disorder. In this review, we provided a comprehensive overview of biomarkers involved in COPD, and potential novel biological therapies that may provide additional therapeutic options for COPD. The complex characteristics of COPD have made the recommendation of a generalized therapy challenging, suggesting that a tailored, personalized strategy may lead to better outcomes. Existing and unmet needs for COPD treatment support the continued development of biological therapies, including additional investigations into the potential clinical applications of this approach.

Palliative Care in End-Stage Chronic Obstructive Pulmonary Disease

2018 ◽  
Author(s):  
Linh My Thi Nguyen
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Palliative Care ◽  
Pulmonary Disease ◽  
Symptom Burden ◽  
Symptom Assessment ◽  
Poor Quality ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
End Stage

Patients with end-stage chronic obstructive pulmonary disease (COPD) experience high symptom burden due to severe dyspnea, fatigue, anxiety, depression, disability, and social isolation, resulting in poor quality of life. The caregiving burden for the family is also severe. Despite high symptom burden, because of limited access and difficulty with prognostication, the quality of care for patients with end-stage COPD who receive palliative care compares poorly to the care received by patients with cancer, and the proportion of COPD patients who receive palliative care is much lower than that of cancer patients. Therefore, patients with COPD receive less palliative care and die following more aggressive treatments at the end of life compared to patients with lung cancer, despite having the same preferences for palliative care. This chapter discusses the key issues related to end-stage COPD, including symptom assessment, management, and hospice eligibility.

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