The 4G/4G PAI-1 genotype is associated with elevated plasma PAI-1 levels regardless of variables of the metabolic syndrome and smoking status. A population-based study in Spanish population

2007 ◽  
Vol 9 (1) ◽  
pp. 134-135 ◽  
Author(s):  
M. J. Martínez-Calatrava ◽  
M. T. Martínez-Larrad ◽  
C. Zabena ◽  
J. L. González-Sánchez ◽  
C. Fernández-Pérez ◽  
...  
2005 ◽  
Vol 6 (1) ◽  
pp. 58
Author(s):  
M. Jozifova ◽  
R. Cifkova ◽  
Z. Skodova ◽  
E. Bojanovska ◽  
V. Adamkova ◽  
...  

2011 ◽  
Vol 2011 ◽  
pp. 1-8 ◽  
Author(s):  
Christopher S. Coffey ◽  
Folkert W. Asselbergs ◽  
Patricia R. Hebert ◽  
Hans L. Hillege ◽  
Qing Li ◽  
...  

Background. We used a random sample (n=2,495) from the population-based Prevention of Renal and Vascular End-stage Disease (PREVEND) study population to examine the association of the metabolic syndrome (Met S) with plasminogen activator inhibitor type 1 (PAI-1) and tissue plasminogen activator (t-PA) antigen levels.Results. The overall prevalence of the Met S was 18%, was dependent on age and gender, and was positively associated with higher antigen levels of both PAI-1 and t-PA. These significant effects were maintained after adjustment for age, gender, BMI, elevated C-reactive protein, smoking status, urinary albumin excretion, and insulin levels. We found no significant interactions between the Met S and other covariates on PAI-1 and t-PA levels.Conclusions. Our study demonstrates that those with the Met S have significantly higher levels of PAI-1 and t-PA antigen, factors known to increase the risk of cardiovascular disease.


2020 ◽  
Vol 21 (5) ◽  
pp. 733-739 ◽  
Author(s):  
Khalaf Kridin ◽  
Arieh Solomon ◽  
Dana Tzur-Bitan ◽  
Giovanni Damiani ◽  
Doron Comaneshter ◽  
...  

2018 ◽  
Vol 12 (3) ◽  
pp. 245-250 ◽  
Author(s):  
Eman F El-Sayed ◽  
Heitham Awadalla ◽  
Sufian K Noor ◽  
Wadie M Elmadhoun ◽  
Amel A Sulaiman ◽  
...  

2011 ◽  
Vol 73 (2) ◽  
pp. 158-165 ◽  
Author(s):  
Pekka Johannes Puustinen ◽  
Hannu Koponen ◽  
Hannu Kautiainen ◽  
Pekka Mäntyselkä ◽  
Mauno Vanhala

2013 ◽  
Vol 78 (2) ◽  
pp. 242-247 ◽  
Author(s):  
Mirjam M. Oosterwerff ◽  
Natasja M. van Schoor ◽  
Paul Lips ◽  
Elisabeth M. W. Eekhoff

Sign in / Sign up

Export Citation Format

Share Document