A prospective randomised controlled trial of perineal repair after childbirth, comparing interrupted chromic catgut to subcuticular prolene for skin closure

Author(s):  
P. M. Doyle ◽  
R. Johanson ◽  
T. Geetha ◽  
P. Wilkinson
BMJ Open ◽  
2019 ◽  
Vol 9 (1) ◽  
pp. e021645
Author(s):  
Zonghui Liu ◽  
Xiangyu Liu ◽  
Lin He ◽  
Xueyuan Yu ◽  
Lu Wang ◽  
...  

IntroductionBased on the principles of the ideal skin closure technique, we previously described a suture technique (wedge-shaped excision and modified buried vertical mattress suture (WE-MBVMS)) that could provide excellent outcomes for the most demanding surfaces. However, adequate clinical comparative evidence supporting improved outcomes is lacking. Thus, the purpose of this protocol is to establish the feasibility of conducting a fully randomised controlled trial (RCT) comparing the clinical effectiveness of WE-MBVMS with a buried intradermal suture (BIS) in closing thoracic incision.Methods and analysisThis study is a feasibility RCT of WE-MBVMS and BIS in patients undergoing surgery for costal cartilage harvesting. Seventy-eight participants are expected to participate in the study and will be randomised in a ratio of 1:1 to WE-MBVMS or BIS. Trial feasibility will be assessed by the number of participants assessed for eligibility, recruitment rates, reasons for ineligibility or non-participation, time for interventions, withdrawal and retention at all follow-up points (3, 6 and 12 months), follow-up rates and reasons for withdrawing from the trial. In addition, clinical data regarding the cosmetic results of scars will be collected to inform the sample size for a fully powered RCT.Ethics and disseminationThis study has been approved by The First Affiliated Hospital of Xi’an Jiaotong University Institutional Review Board (XJTU1AF2017LSK-120). The findings will be published in peer-reviewed journals.Trial registration numberChiCTR-INR-17013335; Pre-results.


Author(s):  
Sebastian Berlit ◽  
Benjamin Tuschy ◽  
Joachim Brade ◽  
Jade Mayer ◽  
Sven Kehl ◽  
...  

2020 ◽  
Vol 106 ◽  
pp. 103553
Author(s):  
Carolina López-Lapeyrere ◽  
Montserrat Solís-Muñoz ◽  
Ana Belén Hernández-López ◽  
Ricardo Rodríguez-Barrientos ◽  
Raquel González-Rubio ◽  
...  

The Lancet ◽  
2002 ◽  
Vol 359 (9325) ◽  
pp. 2217-2223 ◽  
Author(s):  
Christine Kettle ◽  
Robert K Hills ◽  
Peter Jones ◽  
Louisa Darby ◽  
Richard Gray ◽  
...  

2007 ◽  
Vol 89 (3) ◽  
pp. 242-246 ◽  
Author(s):  
DM Ridgway ◽  
F Mahmood ◽  
L Moore ◽  
D Bramley ◽  
PJ Moore

INTRODUCTION Cosmetic acceptability of scar and neck mobility are important outcomes after collar line incision for neck surgery. This randomised, controlled trial compares these parameters in closures using tissue glue (Dermabond™, Ethicon, UK) and skin staples. PATIENTS AND METHODS Patients requiring a collar line incision were randomised to receiving tissue glue or staples for skin closure. Time for closure to be completed was recorded. Mobility of the neck was assessed using a visual analogue scale at 48 h and 1 week after surgery. At 6 weeks, cosmetic appearance was assessed using a linear 1–10 visual analogue scale by the patient, surgeon and an independent blinded assessor. Results were compared using appropriate statistical tests. RESULTS Glued (n = 14) and stapled (n = 15) closures were performed for hemithyroidectomy (n = 8 versus 6), sub-total thyroidectomy (n = 2 versus 4), total thyroidectomy (n = 1 versus 4) and parathyroidectomy (n = 3 versus 1). Closure with tissue glue took significantly longer than with staples (mean, 95 versus 28 s; P < 0.001). Neck mobility scores were comparable at 48 h and 1 week (mean, 4.8 versus 4.4; P = 0.552: and 2.7 versus 2.6; P = 0.886). Cosmetic appearance at 6 weeks was comparable when patient (mean, 1.7 versus 1.8; P = 0.898), surgeon (mean, 2.6 versus 2.3; P = 0.633) and independent assessment (mean, 1.4 versus 1.9; P = 0.365) was performed. CONCLUSIONS The use of glued skin closure may increase the duration of surgery but acceptable neck mobility and wound cosmesis can be achieved by the more rapid application of stapled skin closure in cervicotomy incisions.


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