METABOLIC PARAMETERS OF ONTOGENESIS OF ELECTRICAL ACTIVITY IN THE BRAIN. SODIUM-POTASSIUM ACTIVATED ADENOSINE TRIPHOSPHATASE IN DEVELOPING CHICK EMBRYO BRAIN

1968 ◽  
Vol 15 (10) ◽  
pp. 1217-1224 ◽  
Author(s):  
N. Zaheer ◽  
Z. Iqbal ◽  
G. P. Talwar
1984 ◽  
Vol 14 (1) ◽  
pp. 79-87
Author(s):  
O. V. Bogdanov ◽  
A. A. Smetankin ◽  
S. Ya. Saraev ◽  
E. L. Mikhailenok ◽  
V. V. Ved'

1992 ◽  
Vol 47 (5-6) ◽  
pp. 483-486 ◽  
Author(s):  
Anita Ignatius ◽  
Karlheinz Tempel

In the whole embryo, O6-alkylguanine-DNA alkyltransferase (AT) activity increased until day 9 of development and declined sharply after day 13. AT activity of the liver was greatest between day 12 and day 20 and decreased fast after hatching. In the brain, AT activities reached a maximum at day 17 and 18 and declined sharply after hatching. At two developmental stages with different AT activities (day 10 and day 17) DNA alkylation in the brains was estimated 6, 12, 24 und 48 h after administration of N-methyl-N-nitrosourea in ovo by viscometric measurement of DNA fragmentation. The high AT activities of the chicken embryo brain at the 17th day of development correlated with minor DNA fragmentation following a repair period of 12-24 h. It is suggested that the high basal level of AT in the chick embryo might have a protective function against the persistence of the genotoxic lesion O6-methylguanine during development.


1965 ◽  
Vol 43 (3) ◽  
pp. 369-372 ◽  
Author(s):  
D. J. McCallion ◽  
J. C. Trott

Antiserum against 9-day chick embryo brain was obtained in rabbits. After absorption on chicken serum this antiserum was used in immunoelectrophoretic analysis of the brain of the developing chick. Several embryonic antigens common to all tissues that disappear at hatching were detected. Three adult neural-specific antigens were revealed. At least one neural-specific antigen, present in embryonic brain, disappears before hatching.


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