Pharmacological characterization of cinnamophilin, a novel dual inhibitor of thromboxane synthase and thromboxane A2 receptor

British Journal of Pharmacology ◽

10.1111/j.1476-5381.1994.tb14824.x ◽

1994 ◽

Vol 111 (3) ◽

pp. 906-912 ◽

Author(s):

Sheu-Meei Yu ◽

Tian-Shung Wu ◽

Che-Ming Teng

Keyword(s):

Thromboxane A2 ◽

Pharmacological Characterization ◽

Dual Inhibitor ◽

Thromboxane Synthase ◽

Thromboxane A2 Receptor

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Characterization of the thromboxane synthase pathway product 12-oxoheptadeca-5(Z)-8(E)-10(E)-trienoic acid as a thromboxane A2 receptor antagonist with minimal intrinsic activity

British Journal of Haematology ◽

10.1046/j.1365-2141.1998.00669.x ◽

1998 ◽

Vol 101 (1) ◽

pp. 59-65 ◽

Author(s):

Ruf ◽

Mundkowski ◽

Siegle ◽

Hofmann ◽

Patscheke ◽

...

Keyword(s):

Receptor Antagonist ◽

Thromboxane A2 ◽

Trienoic Acid ◽

Intrinsic Activity ◽

Thromboxane Synthase ◽

Thromboxane A2 Receptor

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Pharmacological Characterization of N-tert-Butyl-N′-[2-(4′-methylphenylamino)-5-nitrobenzenesulfonyl]urea (BM-573), a Novel Thromboxane A2 Receptor Antagonist and Thromboxane Synthase Inhibitor in a Rat Model of Arterial Thrombosis and Its Effects on Bleeding Time

Journal of Pharmacology and Experimental Therapeutics ◽

10.1124/jpet.103.063610 ◽

2004 ◽

Vol 309 (2) ◽

pp. 498-505 ◽

Author(s):

Jean-Michel Dogné ◽

Julien Hanson ◽

Xavier de Leval ◽

Philippe Kolh ◽

Vincent Tchana-Sato ◽

...

Keyword(s):

Receptor Antagonist ◽

Rat Model ◽

Arterial Thrombosis ◽

Bleeding Time ◽

Thromboxane A2 ◽

Pharmacological Characterization ◽

Thromboxane A2 Receptor ◽

Thromboxane Synthase Inhibitor ◽

Synthase Inhibitor

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Pharmacological characterization of EK112, a new combined angiotensin II and thromboxane A2 receptor antagonist

General Pharmacology The Vascular System ◽

10.1016/s0306-3623(00)00046-x ◽

2000 ◽

Vol 34 (1) ◽

pp. 25-31 ◽

Author(s):

Tsong-Long Hwang ◽

Yung-An Yeh ◽

Ji-Wang Chern ◽

Che-Ming Teng

Keyword(s):

Angiotensin Ii ◽

Receptor Antagonist ◽

Thromboxane A2 ◽

Pharmacological Characterization ◽

Thromboxane A2 Receptor

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In Vitro and in Vivo Pharmacological Characterization of BM-613 [N-n-Pentyl-N′-[2-(4′-methylphenylamino)-5-nitrobenzenesulfonyl]urea], a Novel Dual Thromboxane Synthase Inhibitor and Thromboxane Receptor Antagonist

Journal of Pharmacology and Experimental Therapeutics ◽

10.1124/jpet.104.079301 ◽

2004 ◽

Vol 313 (1) ◽

pp. 293-301 ◽

Author(s):

Julien Hanson ◽

Stephanie Rolin ◽

Denis Reynaud ◽

Na Qiao ◽

Leanne P. Kelley ◽

...

Keyword(s):

Receptor Antagonist ◽

Pharmacological Characterization ◽

Thromboxane Synthase ◽

Thromboxane Receptor ◽

Thromboxane Synthase Inhibitor ◽

Thromboxane Receptor Antagonist ◽

Synthase Inhibitor

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Abstract 1919: Pharmacological characterization of BI 847325, a dual inhibitor of MEK and Aurora kinases

10.1158/1538-7445.am2012-1919 ◽

2012 ◽

Author(s):

Patrizia Sini ◽

Ulrich Gürtler ◽

Stephan K. Zahn ◽

Guido Boehmelt ◽

Pilar Garin-Chesa ◽

...

Keyword(s):

Pharmacological Characterization ◽

Dual Inhibitor ◽

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ChemInform Abstract: Synthesis and Biological Characterization of SQBAzide, a Novel Biotinylated Photoaffinity Probe for the Study of the Human Platelet Thromboxane A2 Receptor.

10.1002/chin.200007093 ◽

2010 ◽

Vol 31 (7) ◽

pp. no-no

Author(s):

Therese Halmos ◽

Joseph W. Turek ◽

Guy C. Le Breton ◽

Kostas Antonakis

Keyword(s):

Human Platelet ◽

Thromboxane A2 ◽

Biological Characterization ◽

Thromboxane A2 Receptor ◽

Platelet Thromboxane

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Protective Effects of G 619, a Dual Thromboxane Synthase Inhibitor and Thromboxane A2 Receptor Antagonist, in Splanchnic Artery Occlusion Shock

Journal of Cardiovascular Pharmacology ◽

10.1097/00005344-199201000-00016 ◽

1992 ◽

Vol 19 (1) ◽

pp. 115-119 ◽

Author(s):

Francesco Squadrito ◽

Domenica Altavilla ◽

Basilia Zingarelli ◽

Maria P. Ioculano ◽

Giuseppe M. Campo ◽

...

Keyword(s):

Receptor Antagonist ◽

Thromboxane A2 ◽

Artery Occlusion ◽

Protective Effects ◽

Thromboxane Synthase ◽

Thromboxane A2 Receptor ◽

Thromboxane Synthase Inhibitor ◽

Splanchnic Artery ◽

Synthase Inhibitor

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Pharmacological evaluation of both enantiomers of (R,S)-BM-591 as thromboxane A2 receptor antagonists and thromboxane synthase inhibitors

Prostaglandins & Other Lipid Mediators ◽

10.1016/j.prostaglandins.2004.07.007 ◽

2004 ◽

Vol 74 (1-4) ◽

pp. 75-86 ◽

Author(s):

S. Rolin ◽

J.M. Dogne ◽

C. Vastersaegher ◽

J. Hanson ◽

B. Masereel

Keyword(s):

Thromboxane A2 ◽

Receptor Antagonists ◽

Thromboxane Synthase ◽

Thromboxane A2 Receptor ◽

Pharmacological Evaluation

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Identification and characterization of contact sites between thromboxane A2 receptor and Gαq important for signal transduction impairment

Prostaglandins & Other Lipid Mediators ◽

10.1016/s0090-6980(99)90461-6 ◽

1999 ◽

Vol 59 (1-6) ◽

pp. 226

Author(s):

Valerie Capra ◽

G. Enrico Rovati ◽

Aida Habib ◽

Jacques Maclouf

Keyword(s):

Signal Transduction ◽

Thromboxane A2 ◽

Thromboxane A2 Receptor ◽

Contact Sites ◽

Identification And Characterization

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Characterization of thromboxane A2 receptor signaling in developing rat oligodendrocytes: Nuclear receptor localization and stimulation of myelin basic protein expression

Journal of Neuroscience Research ◽

10.1002/jnr.21061 ◽

2006 ◽

Vol 84 (7) ◽

pp. 1402-1414 ◽

Author(s):

Santosh Ramamurthy ◽

Fozia Mir ◽

Robert M. Gould ◽

Guy C. Le Breton

Keyword(s):

Protein Expression ◽

Nuclear Receptor ◽

Basic Protein ◽

Thromboxane A2 ◽

Thromboxane A2 Receptor ◽

Receptor Localization ◽

Developing Rat ◽

Myelin Basic Protein Expression ◽

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