The Efficacy and Safety of 10,600-nm Carbon Dioxide Fractional Laser for Acne Scars in Asian Patients

Introduction: Pulsed carbon dioxide laser devices are considered highly effective treatment options for skin resurfacing. The aim of this study was to evaluate the efficacy and safety of an ablative 10,600-nm carbon dioxide fractional laser system on moderate to severe acne scarsMaterials and Methods: Forty participants (Fitzpatrick skin types III–IV) ranging from the age group of 25-45 who had moderate to severe acne scars were included in the study.CO2 Fractional laser was used, Unit: eCO2 Lutronic Korea; FDA approved, in 3 sessions at one month interval and 4th and 5th sessions at the interval of 2 months. Comparison was done on a monthly basis for the improvement of scars at one monthly interval and any other symptoms like pain, recovery time for wound healing and complications of laser like hyperpigmentation were noted by asking the patient to fill up a questionaire.Results: All the patients completed the treatment.At the end of the session participants experienced a reduction in the size of the scars. At the first laser session, they presented 10-25%, at the second session 20-45% and at the third session 30-60%. All participants felt an ascending improvement rate during and after the course of treatment. An average improvement of 71% was observed. Twelve of sixteen patients showed mild erythema which was transient and recovered at its own.Conclusions: Fractional Co2 laser ablation provides a safe and effective treatment of moderate to severe facial acne.

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The Safe Delivery of Fractional Ablative Carbon Dioxide Laser Treatment for Acne Scars in Asian Patients Receiving Oral Isotretinoin

Dermatologic Surgery ◽

10.1097/dss.0000000000000185 ◽

2014 ◽

Vol 40 (12) ◽

pp. 1361-1366 ◽

Cited By ~ 28

Author(s):

Hyun Woo Kim ◽

Sung Eun Chang ◽

Jeong Eun Kim ◽

Joo Yeon Ko ◽

Young Suck Ro

Keyword(s):

Carbon Dioxide ◽

Laser Treatment ◽

Carbon Dioxide Laser ◽

Safe Delivery ◽

Asian Patients ◽

Acne Scars ◽

Oral Isotretinoin

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Comparison of a Fractional Microplasma Radio Frequency Technology and Carbon Dioxide Fractional Laser for the Treatment of Atrophic Acne Scars: A Randomized Split-Face Clinical Study

Dermatologic Surgery ◽

10.1111/dsu.12103 ◽

2013 ◽

Vol 39 (4) ◽

pp. 559-566 ◽

Cited By ~ 25

Author(s):

Zhen Zhang ◽

Ye Fei ◽

Xiangdong Chen ◽

Wenli Lu ◽

Jinan Chen

Keyword(s):

Carbon Dioxide ◽

Clinical Study ◽

Radio Frequency ◽

Fractional Laser ◽

Acne Scars ◽

Split Face

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Ablative Fractional CO2 Laser for Facial Atrophic Acne Scars

Facial Plastic Surgery ◽

10.1055/s-0037-1606096 ◽

2018 ◽

Vol 34 (02) ◽

pp. 205-219 ◽

Cited By ~ 11

Author(s):

Yaqin Xu ◽

Yunhua Deng

Keyword(s):

Carbon Dioxide ◽

Carbon Dioxide Laser ◽

Randomized Clinical Trials ◽

Treatment Plan ◽

Acne Vulgaris ◽

Treatment Session ◽

Efficacy And Safety ◽

Acne Scars ◽

Fractional Carbon Dioxide Laser ◽

Comprehensive Search

AbstractAblative fractional carbon dioxide laser resurfacing is a well-established treatment for acne scars. However, there are limited consensus and guidelines regarding the procedure, such as its treatment plan, efficacy, and safety. In this study, we performed a systematic review to assess the efficacy and safety of the fractional carbon dioxide laser treatment procedure, and to provide evidence-based recommendations concerning its practical use on atrophic acne scars. A comprehensive search was performed in, EMBASE, Ovid, Web of Science, and Cochrane databases, using the keywords “scar(s),” “acne vulgaris,” “carbon dioxide,” and “fraction* laser(s)” for the period from January 1987 to December 2016. The initial literature search identified 337 articles. The final selection included 30 studies: 12 retrospective studies and 18 prospective randomized clinical trials. Ablative fractional carbon dioxide laser is an effective therapy for the treatment of acne scars. The treatment session, interval, and parameters should be customized for each patient. Combination therapy should be considered for ice-pick type acne scars. The use of dermocosmetics in pre- and postoperative care may be beneficial to patients.

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