Cortical Benzodiazepine Receptor Binding in Patients with Generalized and Partial Epilepsy

Epilepsia ◽  
1990 ◽  
Vol 31 (6) ◽  
pp. 724-730 ◽  
Author(s):  
Ivanka Savic ◽  
Lennart Widen ◽  
Jan Olof Thorell ◽  
Gunnar Blomqvist ◽  
Kaj Ericson ◽  
...  
Keyword(s):  
Receptor Binding ◽  
Benzodiazepine Receptor ◽  
Partial Epilepsy

Vergleich von Blutfluß und Benzodiazepin-Rezeptorverteilung bei fokaler Epilepsie: Vorläufige Ergebnisse einer SPECT-Studie

1989 ◽  
Vol 28 (05) ◽  
pp. 181-186
Author(s):  
A. Ludolph ◽  
O. Schober ◽  
G. Lottes ◽  
I. Böttger ◽  
H.-F. Beer ◽  
...  
Keyword(s):  
Human Brain ◽  
Receptor Binding ◽  
Brain Area ◽  
Brain Perfusion ◽  
Partial Epilepsy ◽  
Cerebral Lesion ◽  
Receptor Ligand ◽  
Receptor Mapping ◽  
Hmpao Spect ◽  
99Mtc Hmpao

99mTc-HMPAO-SPECT and SPECT with the 123I-labelled benzodiazepine (Bz) receptor ligand Ro 16-0154 were performed in 10 patients suffering from partial epilepsy, without cerebral lesion in MRT or CT. 2 h p.i. of Ro 16-0154 the distribution of activity correlated with the known distribution of Bz- receptors in the human brain. Perfusion and receptor-binding were found decreased in 7 patients of each study in the suspicious brain-area. 123l-labelled Ro 16-0154 is suitable for Bz-receptor mapping by SPECT. The decrease of Bz-receptor binding in epileptic foci, as described in PET-studies, was also detected by SPECT in 7 of 10 patients.

Quantification of central benzodiazepine receptor binding potential in the brain with 123I-iomazenil SPECT

1993 ◽  
Vol 14 (8) ◽  
pp. 634-643 ◽  
Author(s):  
N. P.L.G. VERHOEFF ◽  
B. ERBAS ◽  
O. KAPUCU ◽  
E. BUSEMANN SOKOLE ◽  
H. BLOK ◽  
...  
Keyword(s):  
Receptor Binding ◽  
Benzodiazepine Receptor ◽  
Binding Potential ◽  
Central Benzodiazepine Receptor ◽  
The Brain

Delayed image of iodine-123 iomazenil as a relative map of benzodiazepine receptor binding: The optimal scan time

1996 ◽  
Vol 23 (11) ◽  
pp. 1491-1497 ◽  
Author(s):  
Yoshihiro Onishi ◽  
Yoshiharu Yonekura ◽  
Fumiko Tanaka ◽  
Sadahiko Nishizawa ◽  
Hidehiko Okazawa ◽  
...  
Keyword(s):  
Receptor Binding ◽  
Benzodiazepine Receptor ◽  
Scan Time ◽  
Delayed Image ◽  
Iodine 123

6-Substituted-9-(3-formamidobenzyl)-9H-purines. Benzodiazepine receptor binding activity

1991 ◽  
Vol 28 (4) ◽  
pp. 1099-1104 ◽  
Author(s):  
James L. Kelley ◽  
Ed W. Mclean ◽  
Robert M. Ferris ◽  
James L. Howard
Keyword(s):  
Receptor Binding ◽  
Benzodiazepine Receptor ◽  
Binding Activity ◽  
Receptor Binding Activity

Differential modulation of benzodiazepine receptor binding by ethanol in LS and SS mice

1988 ◽  
Vol 29 (3) ◽  
pp. 471-477 ◽  
Author(s):  
Lawrence G. Miller ◽  
David J. Greenblatt ◽  
Jamie G. Barnhill ◽  
Richard I. Shader
Keyword(s):  
Receptor Binding ◽  
Benzodiazepine Receptor ◽  
Differential Modulation
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