ISOLATION AND CHARACTERIZATION OF THE PHYTOENE DESATURASE GENE AS A POTENTIAL SELECTIVE MARKER FOR GENETIC ENGINEERING OF THE ASTAXANTHIN-PRODUCING GREEN ALGACHLORELLA ZOFINGIENSIS(CHLOROPHYTA)

2008 ◽  
Vol 44 (3) ◽  
pp. 684-690 ◽  
Author(s):  
Junchao Huang ◽  
Jin Liu ◽  
Yantao Li ◽  
Feng Chen
Keyword(s):  
Genetic Engineering ◽  
Phytoene Desaturase ◽  
Selective Marker ◽  
Desaturase Gene ◽  
Isolation And Characterization

scholarly journals Isolation and characterization of fluconazole- and amphotericin B-resistant Candida albicans from blood of two patients with leukemia.

1997 ◽  
Vol 41 (1) ◽  
pp. 196-199 ◽  
Author(s):  
F S Nolte ◽  
T Parkinson ◽  
D J Falconer ◽  
S Dix ◽  
J Williams ◽  
...  
Keyword(s):  
Candida Albicans ◽  
Amphotericin B ◽  
High Dose ◽  
Clinical Settings ◽  
Desaturase Gene ◽  
Isolation And Characterization ◽  
Fluconazole Resistant ◽  
Resistant Strains ◽  
Fluconazole Prophylaxis

Infections with fluconazole-resistant Candida albicans isolate have rarely been described in clinical settings other than oropharyngeal candidiasis in patients with late-stage AIDS. We report on two patients with leukemia who developed fungemia caused by fluconazole-resistant C. albicans after receiving fluconazole prophylaxis (400 mg/day) and empiric amphotericin B therapy (0.5 mg/kg of body weight per day). The fluconazole MICs for the isolates were > or = 64 micrograms/ml, and the isolates were resistant to other azoles and had membrane sterol changes consistent with a mutation in the delta 5,6-sterol desaturase gene. The lack of ergosterol in the cytoplasmic membrane of the fluconazole-resistant strains also imparted resistance to amphotericin B. Both patients were successfully treated with high-dose amphotericin B (1 to 1.25 mg/kg/day) and flucytosine (150 mg/kg/day).

Molecular Characterization of Carotenoid Biosynthesis in Plants: The Phytoene Desaturase Gene in Tomato

1992 ◽  
pp. 11-18 ◽  
Author(s):  
Iris Pecker ◽  
Daniel Chamovitz ◽  
Varda Mann ◽  
Gerhard Sandmann ◽  
Peter Böger ◽  
...  
Keyword(s):  
Molecular Characterization ◽  
Carotenoid Biosynthesis ◽  
Phytoene Desaturase ◽  
Desaturase Gene

Isolation and characterization of mutations affecting expression of theΔ9- fatty acid desaturase gene,OLE1, inSaccharomyces cerevisiae

FEBS Letters ◽  
1997 ◽  
Vol 413 (2) ◽  
pp. 226-230 ◽  
Author(s):  
Ko Fujimori ◽  
Sarintip Anamnart ◽  
Youji Nakagawa ◽  
Shigemi Sugioka ◽  
Daisaku Ohta ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Fatty Acid Desaturase ◽  
Desaturase Gene ◽  
Isolation And Characterization ◽  
Fatty Acid Desaturase Gene

Isolation and Characterization of Two Promoters from Linseed for Genetic Engineering

Crop Science ◽  
1999 ◽  
Vol 39 (6) ◽  
pp. 1696-1701 ◽  
Author(s):  
Ravinder K. Jain ◽  
R. Gail Thompson ◽  
David C. Taylor ◽  
Samuel L. MacKenzie ◽  
Alan McHughen ◽  
...  
Keyword(s):  
Genetic Engineering ◽  
Isolation And Characterization
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